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Invitrogen
ARHGEF4 Monoclonal Antibody (ARHGEF-08), PE
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FIGURE: 1 / 1
ARHGEF4 Antibody (MA5-28621) in Flow
Flow cytometry intracellular staining pattern of of ARHGEF4 in transfected HEK-293 cells stained using anti-ARHGEF4 (ARHGEF-08) PE Monoclonal antibody (Product # MA5-28621), concentration in sample 1 µg/mL (blue) and Mouse IgG1 Isotype Control (MOPC-21) PE antibody (concentration in sample 1 µg/mL, orange).
Product Details
MA5-28621
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
ARHGEF-08
Immunogen
Recombinant fragment of human ARHGEF4 (amino acids 143-271)
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Concentration
0.1 mg/mL
Purification
Size-exclusion chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2745580
Product Specific Information
This antibody recognizes human intracellular protein ARHGEF4 / ASEF1, approx. 80 kDa guanine nucleotide exchange factor specific for Rac1 and Cdc42. The epitope is located in the rough at the region of SH3 domain.
Target Information
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: APC-stimulated guanine nucleotide exchange factor 1; Asef; DKFZp434G2016; Rho guanine nucleotide exchange factor (GEF) 4; Rho guanine nucleotide exchange factor 4
Gene Aliases: ARHGEF4; ASEF; ASEF1; GEF4; KIAA1112; STM6
UniProt ID: (Human) Q9NR80
Entrez Gene ID: (Human) 50649
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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