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ARHGEF5 Polyclonal Antibody

ARHGEF5 Antibody in Immunocytochemistry (ICC/IF)

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ARHGEF5 Antibody (11379-1-AP) in ICC/IF

Immunofluorescent analysis of ( 4% PFA ) fixed HeLa cells using 11379-1-AP (ARHGEF5 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

ARHGEF5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

ARHGEF5 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11379-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ARHGEF5 Fusion Protein Ag1892 (171-519 aa encoded by BC010046)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: VCDVVLNHA PDFRRVYLPY VTNQTYQERT FQSLMNSNSN FREVLEKLES DPVCQRLSLK SFLILPFQRI TRLKLLLQNI LKRTQPGSSE EAEATKAHHA LEQLIRDCNN NVQSMRRTEE LIYLSQKIEF ECKIFPLISQ SRWLVKSGEL TALEFSASPG LRRKLNTRPV HLHLFNDCLL LSRPREGSRF LVFDHAPFSS IRGEKCEMKL HGPHKNLFRL FLRQNTQGAQ AEFLFRTETQ SEKLRWISAL AMPREELDLL ECYNSPQVQC LRAYKPREND ELALEKADVV MVTQQSSDGW LEGVRLSDGE RGWFPVQQVE FISNPEVRAQ NLKEAHRVKT AKLQLVEQQA (171-519 aa encoded by BC010046)

Target Information

This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

ODAM inhibits RhoA-dependent invasion in breast cancer.

Cell biochemistry and function

Lee HK,Choung HW,Yang YI,Yoon HJ,Park IA,Park JC

Thu Oct 01 00:00:00 UTC 2015

ODAM inhibits RhoA-dependent invasion in breast cancer.

Cell biochemistry and function

Lee HK,Choung HW,Yang YI,Yoon HJ,Park IA,Park JC

Thu Oct 01 00:00:00 UTC 2015

Odontogenic Ameloblast-associated Protein (ODAM) Mediates Junctional Epithelium Attachment to Teeth via Integrin-ODAM-Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5)-RhoA Signaling.

The Journal of biological chemistry

Lee HK,Ji S,Park SJ,Choung HW,Choi Y,Lee HJ,Park SY,Park JC

Fri Jun 05 00:00:00 UTC 2015

Odontogenic Ameloblast-associated Protein (ODAM) Mediates Junctional Epithelium Attachment to Teeth via Integrin-ODAM-Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5)-RhoA Signaling.

The Journal of biological chemistry

Lee HK,Ji S,Park SJ,Choung HW,Choi Y,Lee HJ,Park SY,Park JC

Fri Jun 05 00:00:00 UTC 2015

Odontogenic Ameloblast-associated Protein (ODAM) Mediates Junctional Epithelium Attachment to Teeth via Integrin-ODAM-Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5)-RhoA Signaling.

The Journal of biological chemistry

Lee HK,Ji S,Park SJ,Choung HW,Choi Y,Lee HJ,Park SY,Park JC

Fri Jun 05 00:00:00 UTC 2015

Odontogenic Ameloblast-associated Protein (ODAM) Mediates Junctional Epithelium Attachment to Teeth via Integrin-ODAM-Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5)-RhoA Signaling.

The Journal of biological chemistry

Lee HK,Ji S,Park SJ,Choung HW,Choi Y,Lee HJ,Park SY,Park JC

Fri Jun 05 00:00:00 UTC 2015

Co-expression of Rho guanine nucleotide exchange factor 5 and Src associates with poor prognosis of patients with resected non-small cell lung cancer.

Oncology reports

He P,Wu W,Wang H,Liao K,Zhang W,Xiong G,Wu F,Meng G,Yang K

Sun Dec 01 00:00:00 UTC 2013

Co-expression of Rho guanine nucleotide exchange factor 5 and Src associates with poor prognosis of patients with resected non-small cell lung cancer.

Oncology reports

He P,Wu W,Wang H,Liao K,Zhang W,Xiong G,Wu F,Meng G,Yang K

Sun Dec 01 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: ARH5; DKFZp686N1969; Ephexin 3; Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; p60 TIM; Rho guanine nucleotide exchange factor (GEF) 5; Rho guanine nucleotide exchange factor 5; Transforming immortalized mammary oncogene

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Gene Aliases: 2210412D05Rik; AA717842; ARHGEF5; AW495314; GEF5; P60; TIM; TIM1

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UniProt ID: (Human) Q12774, (Mouse) E9Q7D5

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Entrez Gene ID: (Human) 7984, (Mouse) 54324, (Rat) 140898

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Function(s)

guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding GTP binding lipid binding

Process(es)

myeloid dendritic cell chemotaxis actin cytoskeleton organization regulation of actin cytoskeleton organization regulation of Rho protein signal transduction intracellular signal transduction regulation of GTPase activity positive regulation of JUN kinase activity positive regulation of GTPase activity positive regulation of sequence-specific DNA binding transcription factor activity regulation of cytoskeleton organization positive regulation of stress fiber assembly regulation of ERK1 and ERK2 cascade positive regulation of podosome assembly positive regulation of protein import

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ARHGEF5 Polyclonal Antibody

ARHGEF5 Antibody (11379-1-AP) in ICC/IF

Product Details

11379-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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