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Abnova
ARHGEF5 Monoclonal Antibody (3A12-B5)
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Product Details
H00007984-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3A12-B5
Immunogen
ARHGEF5 (AAH14555, 1 a.a. approximately 519 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: MGGFSRRCSK LINSSQLLYQ EYSDVVLNKE IQSQQRLESL SETPGPSSPR QPRKALVSSE SYLQRLSMAS SGSLWQEIPV VRNSTVLLSM THEDQKLQEV KFELIVSEAS YLRSLNIAVD HFQLSTSLRA TLSNQEHQWL FSRLQDVRDV SATFLSDLEE NFENNIFSFQ VCDVVLNHAP DFRRVYLPYV TNQTYQERTF QSLMNSNSNF REVLEKLESD PVCQRLSLKS FLILPFQRIT RLKLLLQNIL KRTQPGSSEE AEATKAHHAL EQLIRDCNNN VQSMRRTEEL IYLSQKIEFE CKIFPLISQS RWLVKSGELT ALEFSASPGL RRKLNTRPVH LHLFNDCLLL SRPREGSRFL VFDHAPFSSI RGEKCEMKLH GPHKNLFRLF LRQNTQGAQA EFLFRTETQS EKLRWISALA MPREELDLLE CYNSPQVQCL RAYKPRENDE LALEKADVVM VTQQSSDGWL EGVRLSDGER GWFPVQQVEF ISNPEVRAQN LKEAHRVKTA KLQLVEQQA
Target Information
This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARH5; DKFZp686N1969; Ephexin 3; Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; p60 TIM; Rho guanine nucleotide exchange factor (GEF) 5; Rho guanine nucleotide exchange factor 5; Transforming immortalized mammary oncogene
Gene Aliases: ARHGEF5; GEF5; P60; TIM; TIM1
UniProt ID: (Human) Q12774
Entrez Gene ID: (Human) 7984
myeloid dendritic cell chemotaxis
actin cytoskeleton organization
regulation of actin cytoskeleton organization
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of GTPase activity
positive regulation of JUN kinase activity
positive regulation of GTPase activity
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of cytoskeleton organization
positive regulation of stress fiber assembly
regulation of ERK1 and ERK2 cascade
positive regulation of podosome assembly
positive regulation of protein import
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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