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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The protein encoded by this gene is a Rho-like GTPase that switches between the active state and inactive state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy, also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Cdc42 guanine nucleotide exchange factor (GEF) 9; Collybistin; collybistin I; hPEM-2 collybistin; PEM-2 homolog; Rac/Cdc42 guanine nucleotide exchange factor 9; Rho guanine nucleotide exchange factor 9
Gene Aliases: 9630036L12Rik; A230067K14; ARHDH9; ARHGEF9; COLLYBISTIN; EIEE8; HPEM-2; KIAA0424; mKIAA0424; PEM-2; PEM2
UniProt ID: (Human) O43307, (Mouse) Q3UTH8, (Rat) Q9QX73
Entrez Gene ID: (Human) 23229, (Mouse) 236915, (Rat) 66013
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