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Invitrogen
ARIH2 Polyclonal Antibody
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FIGURE: 1 / 3
ARIH2 Antibody (PA5-81490) in ICC/IF
Immunofluorescence staining of ARIH2 in HeLa cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with ARIH2 Polyclonal Antibody (Product # PA5-81490, 1:1,000) at 4°C overnight. Then cells were stained with the Alexa Fluor®594-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to nucleus.
Product Details
PA5-81490
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the C-terminus of the Human ARIH2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2788697
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human ARIH2.
Target Information
E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: all-trans retinoic acid inducible RING finger; ARI-2; ariadne homolog 2; E3 ubiquitin-protein ligase ARIH2; FLJ10938; FLJ33921; OTTHUMP00000210388; protein ariadne-2 homolog; Triad1 protein
Gene Aliases: ARI2; ARIH2; HT005; TRIAD1
UniProt ID: (Human) O95376
Entrez Gene ID: (Human) 10425
protein polyubiquitination
multicellular organism development
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
developmental cell growth
protein K63-linked ubiquitination
protein K48-linked ubiquitination
hematopoietic stem cell proliferation
positive regulation of protein targeting to mitochondrion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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