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OriGene
ARIH2 Monoclonal Antibody (OTI1B2), TrueMAB™
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Product Details
CF811978
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1B2
Immunogen
Human recombinant protein fragment corresponding to amino acids 201-493 of human ARIH2 (NP_006312) produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
See Label
Purification
Protein A/G
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: all-trans retinoic acid inducible RING finger; ARI-2; ariadne 2; ariadne homolog 2; E3 ubiquitin-protein ligase ARIH2; FLJ10938; FLJ33921; OTTHUMP00000210388; protein ariadne-2 homolog; Triad1 protein; UbcM4-interacting protein 48
Gene Aliases: AI843547; ARI2; ARIH2; HT005; TRIAD1; UIP48
UniProt ID: (Human) O95376, (Mouse) Q9Z1K6
Entrez Gene ID: (Human) 10425, (Mouse) 23807, (Rat) 316005
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin conjugating enzyme binding
ubiquitin protein ligase activity
nucleic acid binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
protein polyubiquitination
ubiquitin-dependent protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
developmental cell growth
protein K63-linked ubiquitination
protein K48-linked ubiquitination
hematopoietic stem cell proliferation
positive regulation of protein targeting to mitochondrion
multicellular organism development
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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