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Immunogen sequence: ALKDRKWQIF KTSATKGTGL DEAMEWLVET LKSRQ
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADP-ribosylation factor like GTPase 1; ADP-ribosylation factor-like 1; ADP-ribosylation factor-like protein 1
Gene Aliases: ARFL1; ARL1
UniProt ID: (Human) P40616
Entrez Gene ID: (Human) 400
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