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Invitrogen
ARL6 Polyclonal Antibody
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Product Details
PA5-53983
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ARL6. Recombinant protein control fragment (Product #RP-91729).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2638202
Product Specific Information
Immunogen sequence: FVIDSSDRLR MVVAKEELDT LLNHPDIKHR RIPILFFANK MDLRDAVTSV KVSQLLCLEN IKDKPWHICA SDAIKGEGLQ EGVDWLQDQI QTV
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
Target Information
The protein encoded by this gene belongs to the ARF-like (ADP ribosylation factor-like) sub-family of the ARF family of GTP-binding proteins which are involved in regulation of intracellular traffic. Mutations in this gene are associated with Bardet-Biedl syndrome (BBS). Alternative splicing results in multiple transcript variants of this gene. A vision-specific transcript encoding a different protein has been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosylation factor-like protein 6; Bardet-Biedl syndrome 3 protein
Gene Aliases: ARL6; BBS3; RP55
UniProt ID: (Human) Q9H0F7
Entrez Gene ID: (Human) 84100
protein targeting to membrane
small GTPase mediated signal transduction
determination of left/right symmetry
brain development
visual perception
regulation of smoothened signaling pathway
retina layer formation
Wnt signaling pathway
melanosome transport
cilium assembly
fat cell differentiation
intermembrane transport
protein polymerization
protein localization to cilium
protein localization to nonmotile primary cilium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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