Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGGPRGAGWV AAGLLLGAGA CYCIYRLTRG RRRGDRELGI RSSKSAEDLT DGSYDDVLNA EQLQKLLYLL ESTEDPVIIE RALITLGNNA AFSVNQAIIR ELGGIPIVAN KINHSNQSIK EKALNALNNL SVNVENQIKI KIYISQVCED VFSGSLNSAV QLAGLTLLTN MTVTNDHQHM LHSYITDLFQ VLLTGNGNTK VQVLKLLLNL SENPAMTEGL LRAQVDSSFL SLYDSHVAKE ILLRVLTLFQ NIKNCLKIEG HLAVQPTFTE GSLFFLLHGE ECAQKIRALV DHHDAEVKEK VVTIIPKI
This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Armadillo repeat-containing protein 10; specific splicing variant involved in hepatocarcinogenesis; Splicing variant involved in hepatocarcinogenesis protein
Gene Aliases: ARMC10; PNAS-112; PNAS112; PSEC0198; SVH
UniProt ID: (Human) Q8N2F6
Entrez Gene ID: (Human) 83787
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