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Invitrogen
ARNT2 Polyclonal Antibody
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Product Details
PA5-72632
Product Specifications
Species Reactivity
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 475-501 amino acids from the Central region of DANRE arnt2
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2718486
Target Information
AhR, ARNT1, ARNT2 and BMAL1 are members of a family of transcription factors that contain a basic helix-loop-helix motif and a common "PAS" motif. The aromatic (aryl) hydrocarbon receptor, AhR, is a ligand dependent transcription factor that interacts with specific DNA sequences termed xenobiotic responsive elements (XREs) to activate several genes including CYP1A1, glutathione S-transferase Ya subunit and DT-diaphorase. The Ah receptor nuclear translocator proteins (Arnt 1 or Arnt 2) are required for ligand-dependent nuclear translocation of the Ah receptor and are also necessary for Ah receptor binding to the XRE element. BMAL1 (Brain and Muscle Arnt-like protein 1), also designated Arnt 3, TIC, JAP3 or MOP-3, has been shown to dimerize with Clock and bind to the promoter region of mPer1, suggesting that this protein plays a role in regulation of circadian oscillation in mammals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ah receptor nuclear translocator; Arnt; ARNT 2; ARNT protein 2; ARNT2A; ARNT2b; ARNT2c; Aryl hydrocarbon receptor nuclear translocator 2; unm t30256; unm_t30256
Gene Aliases: Arnt; arnt2; arnt2a; arnt2X; chunp6921; zfARNT2; zfARNT2a; zfARNT2b; zfARNT2c
UniProt ID: (Zebrafish) Q9DG12
Entrez Gene ID: (Zebrafish) 64277
response to hypoxia
cardiac ventricle morphogenesis
regulation of transcription, DNA-templated
signal transduction
axon guidance
brain development
diencephalon development
ventricular system development
hypothalamus cell differentiation
positive regulation of transcription, DNA-templated
swim bladder inflation
dopaminergic neuron differentiation
liver morphogenesis
cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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