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Invitrogen
ARPP19 Polyclonal Antibody
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Product Details
PA5-63357
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ARPP19. Recombinant protein control fragment (Product #RP-101747).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2638241
Product Specific Information
Immunogen sequence: MSAEVPEAAS AEEQKEMEDK VTSPEKAEEA K
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARPP-19; cAMP regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein 19; cAMP-regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein, 19kDa; cyclic AMP phosphoprotein, 19 kD
Gene Aliases: ARPP-16; ARPP-19; ARPP16; ARPP19; ENSAL
UniProt ID: (Human) P56211
Entrez Gene ID: (Human) 10776
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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