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Invitrogen
ARPP19 Polyclonal Antibody
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Product Details
PA5-70811
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the N-terminal of mouse ARPP19
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2690896
Target Information
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARPP-19; cAMP-regulated phosphoprotein 19; cAMP-regulated phosphoprotein ARPP-19; cyclic AMP phosphoprotein, 19 kDa; cyclic AMP phosphoprotein, 19kD
Gene Aliases: 19kDa; 2700024H10Rik; ARPP-19; Arpp12; Arpp19; AW559096
UniProt ID: (Mouse) P56212
Entrez Gene ID: (Mouse) 59046
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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