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Proteintech
ARSB Polyclonal Antibody
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Product Details
13227-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARSB Fusion Protein Ag4083 (47-413 aa encoded by BC029051)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LVFLLADDL GWNDVGFHGS RIRTPHLDAL AAGGVLLDNY YTQPLCTPSR SQLLTGRYQI RTGLQHQIIW PCQPSCVPLD EKLLPQLLKE AGYTTHMVGK WHLGMYRKEC LPTRRGFDTY FGYLLGSEDY YSHERCTLID ALNVTRCALD FRDGEEVATG YKNMYSTNIF TKRAIALITN HPPEKPLFLY LALQSVHEPL QVPEEYLKPY DFIQDKNRHH YAGMVSLMDE AVGNVTAALK SSGLWNNTVF IFSTDNGGQT LAGGNNWPLR GRKWSLWEGG VRGVGFVASP LLKQKGVKNR ELIHISDWLP TLVKLARGHT NGTKPLDGFD VWKTISEGSP SPRIELLHNI DPNFVDSSPY WPECSLLL (47-413 aa encoded by BC029051 )
Target Information
Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Arylsulfatase B; Arylsulfatase B (MPS VI); arylsulfatase B complex; arylsulfatase B regulation; arylsulfatase B structural; arylsulfatase B temporal regulation; ASB; G4S; N-acetylgalactosamine-4-sulfatase
Gene Aliases: 1110007C02Rik; AI480648; ARSB; As-1; As-1r; As-1s; As-1t; As1; As1-r; As1-s; As1-t; ASB; Asr-1; Ast-1; G4S; MPS6
UniProt ID: (Human) P15848, (Rat) P50430, (Mouse) P50429
Entrez Gene ID: (Human) 411, (Rat) 25227, (Mouse) 11881
glycosphingolipid metabolic process
autophagy
lysosome organization
lysosomal transport
central nervous system development
response to nutrient
response to pH
regulation of epithelial cell migration
positive regulation of neuron projection development
chondroitin sulfate catabolic process
response to estrogen
post-translational protein modification
response to methylmercury
colon epithelial cell migration
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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