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Osenses
ARX Polyclonal Antibody
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Product Details
OSA00157W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from human Homeobox protein ARX conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: ARX.
Target Information
Arx contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This protein is thought to be involved in CNS development. Mutations in the Arx gene cause X-linked mental retardation and epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Aristaless-related homeobox; aristaless-related homeobox, X-linked; arx {ECO:0000250|UniProtKB:Q96QS3}; cancer/testis antigen 121; Homeobox protein ARX
Gene Aliases: ARX; CT121; EIEE1; ISSX; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1; PRTS; RGD1562672
UniProt ID: (Human) Q96QS3, (Mouse) O35085, (Rat) A6YP92
Entrez Gene ID: (Human) 170302, (Mouse) 11878, (Rat) 317268
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
chromatin binding
molecular_function
sequence-specific DNA binding
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
axon guidance
positive regulation of gene expression
globus pallidus development
cerebral cortex tangential migration
embryonic olfactory bulb interneuron precursor migration
cell proliferation in forebrain
cerebral cortex GABAergic interneuron migration
regulation of cell proliferation
lipid digestion
positive regulation of organ growth
epithelial cell fate commitment
neuron migration
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
nervous system development
biological_process
olfactory bulb development
cell differentiation
forebrain development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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