Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
ASCL2 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 3
ASCL2 Antibody (PA5-40474) in WB
Western blot was performed using Anti-ASCL2 Polyclonal Antibody (Product # PA5-40474) and a 26 kDa band corresponding to ASCL2 was observed in cell lines tested except SH-SY5Y and A-375. Modified whole cell extracts (30 µg lysate) of DU 145 (Lane 1), PANC-1 (Lane 2), HT-29 (Lane 3), SH-SY5Y (Lane 4) and A-375 (Lane 5) were electrophoresed using Novex® NuPAGE® 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (Product #... View More
Product Details
PA5-40474
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human ASCL2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2605819
Product Specific Information
Peptide sequence: QALRQHVPHG GASKKLSKVE TLRSAVEYIR ALQRLLAEHD AVRNALAGGL
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 92%; Rabbit: 77%; Rat: 100%; Zebrafish: 77%
Target Information
This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: achaete-scute complex homolog 2; achaete-scute complex-like 2; Achaete-scute homolog 2; ASH-2; bHLHa45; Class A basic helix-loop-helix protein 45; H M bHLHa45; mammalian achaete/scute homologue 2; Mash2
Gene Aliases: ASCL2; ASH2; BHLHA45; HASH2; MASH2
UniProt ID: (Human) Q99929
Entrez Gene ID: (Human) 430
negative regulation of transcription from RNA polymerase II promoter
response to hypoxia
placenta development
transcription, DNA-templated
regulation of transcription, DNA-templated
negative regulation of Schwann cell proliferation
somatic stem cell population maintenance
regulation of neurogenesis
spongiotrophoblast differentiation
spongiotrophoblast layer development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support