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Immunogen sequence: VDLRFVACQM ELLHSNGSQR TCCPVNWVEH QGSCYWFSHS GKAWAEAEKY CQLENAHLVV INSWEEQKFI VQHTNPFNTW IGLTDSDGSW KWVDGTDYRH NYKNWAVTQP DNWHGHELGG SEDCVEVQPD GRWNDDFCLQ VYRWVCEKRR NATGEVA; Positive Samples: Mouse liver, Rat liver; Cellular Location: Membrane, Single-pass type II membrane protein
ASGR2 is a cell surface receptor that binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ANCO-2; ANCO1; ASGP-R 2; ASGPR 2; Asialoglycoprotein receptor 2; GAC-1; Hepatic lectin 2; hepatic lectin 2 RHL2; hepatic lectin 2, RHL2; Hepatic lectin R2/3; HL-2; mHL-2; Nbla00144; RHL-2
Gene Aliases: ASGPR2; Asgr; Asgr-2; Asgr2
UniProt ID: (Mouse) P24721, (Rat) P08290
Entrez Gene ID: (Mouse) 11890, (Rat) 29403
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