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Product Details
12003-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ASIC4 Fusion Protein Ag2664 (299-647 aa encoded by BC010439)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: QLADMLKSC NFSGHHCSAS NFSVVYTRYG KCYTFNADPR SSLPSRAGGM GSGLEIMLDI QQEEYLPIWR ETNETSFEAG IRVQIHSQEE PPYIHQLGFG VSPGFQTFVS CQEQRLTYLP QPWGNCRAES ELREPELQGY SAYSVSACRL RCEKEAVLQR CHCRMVHMPD SLGGGPEGPC FCPTPCNLTR YGKEISMVRI PNRGSARYLA RKYNRNETYI RENFLVLDVF FEALTSEAME QRAAYGLSAL LGDLGGQMGL FIGASILTLL EILDYIYEVS WDRLKRVWRR PKTPLRTSTG GISTLGLQEL KEQSPCPSLG RAEGGGVSSL LPNHHHPHGP PGGLFEDFAC (299-647 aa encoded by BC010439)
Target Information
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acid sensing (proton gated) ion channel family member 4; acid sensing ion channel family member 4; acid-sensing (proton-gated) ion channel family member 4; Acid-sensing ion channel 4; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4, pituitary; amiloride-sensitive cation channel family member 4, pituitary; ASIC4; brain sodium channel 4; MGC17248; MGC24860; putative acid-sensing ion channel; spinal chord ASIC; Spinal cord ASIC
Gene Aliases: ACCN4; ASIC4; BNAC4; Spasic
UniProt ID: (Human) Q96FT7, (Rat) Q9JHS6, (Mouse) Q7TNS7
Entrez Gene ID: (Human) 55515, (Rat) 63882, (Mouse) 241118
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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