Proteintech

ASRGL1 Polyclonal Antibody

ASRGL1 Antibody in Immunocytochemistry (ICC/IF)

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ASRGL1 Antibody (11400-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 11400-1-AP (ASRGL1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

ASRGL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

ASRGL1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11400-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ASRGL1 Fusion Protein Ag1955 (1-308 aa encoded by BC021295)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MNPIVVVHG GGAGPISKDR KERVHQGMVR AATVGYGILR EGGSAVDAVE GAVVALEDDP EFNAGCGSVL NTNGEVEMDA SIMDGKDLSA GAVSAVQCIA NPIKLARLVM EKTPHCFLTD QGAAQFAAAM GVPEIPGEKL VTERNKKRLE KEKHEKGAQK TDCQKNLGTV GAVALDCKGN VAYATSTGGI VNKMVGRVGD SPCLGAGGYA DNDIGAVSTT GHGESILKVN LARLTLFHIE QGKTVEEAAD LSLGYMKSRV KGLGGLIVVS KTGDWVAKWT STSMPWAAAK DGKLHFGIDP DDTTITDLP (1-308 aa encoded by BC021295 )

Target Information

ALP is found in a variety of tumors but only occasionally in normal tissues. Ovarian cancers are highly positive. ALP is further found in brain tumors, some colonic cancers, some lung cancers, some prostate cancers, uterine cancers, some breast cancers and some thyroid cancers. It was not found in serum.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Proteomics and transcriptomics profiling reveals distinct aspects of kidney stone related genes in calculi rats.

BMC genomics

Zhu W,Qiong D,Yanli G,Min L,Ying Z,Qiyi H,Shenping Z,Xisheng W,Hui L

Fri Mar 17 00:00:00 UTC 2023

Fibroblast ferroptosis is involved in periodontitis-induced tissue damage and bone loss.

International immunopharmacology

Xing L,Dong W,Chen Y,Dai W,Xiao X,Liu Z,Zhang X,Bai D,Xu H

Sun Jan 01 00:00:00 UTC 2023

A Mouse Model with Ablated Asparaginase and Isoaspartyl Peptidase 1 (Asrgl1) Develops Early Onset Retinal Degeneration (RD) Recapitulating the Human Phenotype.

Genes

Biswas P,Berry AM,Zawaydeh Q,Bartsch DG,Raghavendra PB,Hejtmancik JF,Khan NW,Riazuddin SA,Ayyagari R

Wed Aug 17 00:00:00 UTC 2022

MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.

BMC musculoskeletal disorders

Xu P,Chang J,Ma G,Liao F,Xu T,Wu Y,Yin Z

Sat Nov 26 00:00:00 UTC 2022

Oocyte Meiotic Competence in the Domestic Cat Model: Novel Roles for Nuclear Proteins BRD2 and NPM1.

Frontiers in cell and developmental biology

Chavez DR,Lee PC,Comizzoli P

Tue Jun 08 00:00:00 UTC 2021

ASRGL1 Correlates With Immune Cell Infiltration in Hepatocellular Carcinoma and Can Serve as a Prognostic Biomarker.

Frontiers in oncology

Xue C,Gao P,Cui X,Zhang X,Lei J,Li R,Zhu C,Qin X

Sun Apr 24 00:00:00 UTC 2022

Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.

Toxicology and applied pharmacology

Wang Y,Chen J,Chen J,Dong C,Yan X,Zhu Z,Lu P,Song Z,Liu H,Chen S

Tue Dec 15 00:00:00 UTC 2020

Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.

Toxicology and applied pharmacology

Wang Y,Chen J,Chen J,Dong C,Yan X,Zhu Z,Lu P,Song Z,Liu H,Chen S

Tue Dec 15 00:00:00 UTC 2020

Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.

Toxicology and applied pharmacology

Wang Y,Chen J,Chen J,Dong C,Yan X,Zhu Z,Lu P,Song Z,Liu H,Chen S

Tue Dec 15 00:00:00 UTC 2020

Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling.

Toxicology and applied pharmacology

Wang Y,Chen J,Chen J,Dong C,Yan X,Zhu Z,Lu P,Song Z,Liu H,Chen S

Tue Dec 15 00:00:00 UTC 2020

Ghrelin Fights Against Titanium Particle-Induced Inflammatory Osteolysis Through Activation of β-Catenin Signaling Pathway.

Inflammation

Qu R,Chen X,Yuan Y,Wang W,Qiu C,Liu L,Li P,Zhang Z,Vasilev K,Liu L,Hayball J,Zhao Y,Li Y,Li W

Tue Oct 01 00:00:00 UTC 2019

As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid.

Cell metabolism

Pavlova NN,Hui S,Ghergurovich JM,Fan J,Intlekofer AM,White RM,Rabinowitz JD,Thompson CB,Zhang J

Tue Feb 06 00:00:00 UTC 2018

As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid.

Cell metabolism

Pavlova NN,Hui S,Ghergurovich JM,Fan J,Intlekofer AM,White RM,Rabinowitz JD,Thompson CB,Zhang J

Tue Feb 06 00:00:00 UTC 2018

Baicalin increases hair follicle development by increasing canonical Wnt/β‑catenin signaling and activating dermal papillar cells in mice.

International journal of molecular medicine

Xing F,Yi WJ,Miao F,Su MY,Lei TC

Sun Apr 01 00:00:00 UTC 2018

Extracellular vesicles are independent metabolic units with asparaginase activity.

Nature chemical biology

Iraci N,Gaude E,Leonardi T,Costa ASH,Cossetti C,Peruzzotti-Jametti L,Bernstock JD,Saini HK,Gelati M,Vescovi AL,Bastos C,Faria N,Occhipinti LG,Enright AJ,Frezza C,Pluchino S

Fri Sep 01 00:00:00 UTC 2017

Extracellular vesicles are independent metabolic units with asparaginase activity.

Nature chemical biology

Iraci N,Gaude E,Leonardi T,Costa ASH,Cossetti C,Peruzzotti-Jametti L,Bernstock JD,Saini HK,Gelati M,Vescovi AL,Bastos C,Faria N,Occhipinti LG,Enright AJ,Frezza C,Pluchino S

Fri Sep 01 00:00:00 UTC 2017

A missense mutation in ASRGL1 is involved in causing autosomal recessive retinal degeneration.

Human molecular genetics

Biswas P,Chavali VR,Agnello G,Stone E,Chakarova C,Duncan JL,Kannabiran C,Homsher M,Bhattacharya SS,Naeem MA,Kimchi A,Sharon D,Iwata T,Riazuddin S,Reddy GB,Hejtmancik JF,Georgiou G,Riazuddin SA,Ayyagari R

Wed Jun 15 00:00:00 UTC 2016

A missense mutation in ASRGL1 is involved in causing autosomal recessive retinal degeneration.

Human molecular genetics

Wed Jun 15 00:00:00 UTC 2016

Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways.

Amino acids

Yuan ZS,Zhou YZ,Liao XB,Luo JW,Shen KJ,Hu YR,Gu L,Li JM,Tan CM,Chen HM,Zhou XM

Tue Dec 01 00:00:00 UTC 2015

Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways.

Amino acids

Yuan ZS,Zhou YZ,Liao XB,Luo JW,Shen KJ,Hu YR,Gu L,Li JM,Tan CM,Chen HM,Zhou XM

Tue Dec 01 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: asparaginase-like 1; asparaginase-like 1 protein; Asparaginase-like protein 1; Asparaginase-like sperm autoantigen; Beta-aspartyl-peptidase; FLJ22316; Glial asparaginase; Isoaspartyl dipeptidase; Isoaspartyl peptidase/L-asparaginase; L-asparaginase; L-asparagine amidohydrolase; testis secretory sperm-binding protein Li 242mP

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Gene Aliases: 2410004D18Rik; ALP; ALP1; ASRGL1; AU040643; AW060375; CRASH; Gliap; Hiob; Hiob2

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UniProt ID: (Human) Q7L266, (Rat) Q8VI04, (Mouse) Q8C0M9

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Entrez Gene ID: (Human) 80150, (Rat) 246307, (Mouse) 66514

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Function(s)

N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity asparaginase activity beta-aspartyl-peptidase activity peptidase activity hydrolase activity

Process(es)

proteolysis L-phenylalanine catabolic process asparagine catabolic process via L-aspartate

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ASRGL1 Polyclonal Antibody

ASRGL1 Antibody (11400-1-AP) in ICC/IF

Product Details

11400-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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