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Invitrogen
ASXL2 Polyclonal Antibody
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Product Details
PA5-68361
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic protein corresponding to residues near the C terminal of human ASXL2.
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2688497
Target Information
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: additional sex combs like 2; additional sex combs like transcriptional regulator 2; Additional sex combs-like protein 2; polycomb group protein ASXH2; Putative Polycomb group protein ASXL2
Gene Aliases: ASXH2; ASXL2; KIAA1685
UniProt ID: (Human) Q76L83
Entrez Gene ID: (Human) 55252
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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