Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: DKWYGESQK LAAAVFSLAI KLQPSIIFID EIDSFLRNRS SSDHEATAMM KAQFMSLWDG LDTDHSCQVI VMGATNRPQD LDSAIMRRMP TRFHINQPAL KQREAILKLI LKNENVDRHV DLLEVAQETD GFSGSDLKEM CRDAALLCVR EYVNSTSEES HDEDEIRPVQ QQDLHRAIEK MKKSKDAAFQ NVLTHVCLD (164-361 aa encoded by BC010868)
ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AAA+ ATPase Thorase; ATPase family AAA domain-containing protein 1; ATPase Thorase; FLJ14600; hATAD1; Neuroprotective protein 6; Outer mitochondrial transmembrane helix translocase; Thorase
Gene Aliases: 4921525H23Rik; Ab2-088; AFDC1; ATAD1; AW107648; FNP001; Npg6; THORASE
UniProt ID: (Human) Q8NBU5, (Mouse) Q9D5T0, (Rat) Q505J9
Entrez Gene ID: (Human) 84896, (Mouse) 67979, (Rat) 309532
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