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Immunogen sequence: NVDRHVDLLE VAQETDGFSG SDLKEMCRDA ALLCVREYVN STSEESHDED EIRPVQQQDL HRAIEKMKKS KDAAFQ
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AAA+ ATPase Thorase; ATPase family AAA domain-containing protein 1; ATPase Thorase; FLJ14600; hATAD1; Outer mitochondrial transmembrane helix translocase; Thorase
Gene Aliases: AFDC1; ATAD1; FNP001; THORASE
UniProt ID: (Human) Q8NBU5
Entrez Gene ID: (Human) 84896
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