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Immunogen sequence: KAERENADII REQIRLKASE HRQTVLESIR TA
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.
ATAD3B is a member of the AAA ATPase family, a family of proteins that catalyze ATP into ADP and are involved in several cellular functions such as cell-cycle regulation, protein proteolysis and transport. The AAA ATPase family is characterized by a highly conserved AAA motif containing Walker homology sequences and imparting ATPase activity. Mitochondrial membrane proteins ATAD3A/B contribute to the stabilization of nucleoids and may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The gene encoding ATAD3A/B/C maps to human chromosome 1 and has been suggested to be an anti-apoptotic marker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AAA-ATPase TOB3; AAA-TOB3; ATPase family AAA domain-containing protein 3B; RP4-628J24.3
Gene Aliases: AAA-TOB3; ATAD3B; KIAA1273; TOB3
UniProt ID: (Human) Q5T9A4
Entrez Gene ID: (Human) 83858
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