Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
OSA00019W-150UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from c-terminal region of human ATG7 conjugated to blue carrier protein has been used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: ATG7.
Target Information
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: APG7-like; ATG12-activating enzyme E1 ATG7; ATG7 autophagy related 7 homolog; autophagy related 7 homolog; autophagy-related 7; Autophagy-related protein 7; DKFZp434N0735; hAGP7; Ubiquitin-activating enzyme E1-like protein; Ubiquitin-like modifier-activating enzyme ATG7
Gene Aliases: 1810013K23Rik; Agp7; APG7-LIKE; APG7L; ATG7; Atg7l; Gm21553; GSA7
UniProt ID: (Human) O95352, (Rat) Q641Y5, (Mouse) Q9D906
Entrez Gene ID: (Human) 10533, (Rat) 312647, (Mouse) 74244
cellular protein modification process
protein lipidation
C-terminal protein lipidation
cellular response to nitrogen starvation
cellular response to starvation
positive regulation of autophagy
protein transport
macroautophagy
positive regulation of macroautophagy
protein ubiquitination
positive regulation of protein modification process
piecemeal microautophagy of nucleus
suppression by virus of host autophagy
positive regulation of apoptotic process
late nucleophagy
positive regulation of protein catabolic process
defense response to virus
membrane fusion
cellular response to hyperoxia
regulation of mitophagy
mitophagy
liver development
cellular amino acid metabolic process
autophagy
organelle organization
mitochondrion organization
adult walking behavior
post-embryonic development
cerebellar Purkinje cell layer development
pyramidal neuron development
central nervous system neuron axonogenesis
cerebral cortex development
protein catabolic process
neuron projection development
regulation of protein ubiquitination
protein modification by small protein conjugation
negative stranded viral RNA replication
response to starvation
negative regulation of apoptotic process
neurological system process
cardiac muscle cell development
membrane organization
positive regulation of mucus secretion
negative regulation of histone H4-K16 acetylation
autophagosome assembly
transport
regulation of cell development
negative regulation of cell death
regulation of hemopoiesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support