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Invitrogen
ATG7 Recombinant Rabbit Monoclonal Antibody (SC06-30)
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Product Details
MA5-32221
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SC06-30
Immunogen
Synthetic peptide within Human Apg7 aa 654-703
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2809507
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: APG7-like; ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7; DKFZp434N0735; hAGP7; Ubiquitin-activating enzyme E1-like protein; Ubiquitin-like modifier-activating enzyme ATG7
Gene Aliases: APG7-LIKE; APG7L; ATG7; GSA7
UniProt ID: (Human) O95352
Entrez Gene ID: (Human) 10533
cellular protein modification process
protein lipidation
C-terminal protein lipidation
cellular response to nitrogen starvation
cellular response to starvation
positive regulation of autophagy
protein transport
macroautophagy
positive regulation of macroautophagy
protein ubiquitination
positive regulation of protein modification process
piecemeal microautophagy of nucleus
suppression by virus of host autophagy
positive regulation of apoptotic process
late nucleophagy
positive regulation of protein catabolic process
defense response to virus
membrane fusion
cellular response to hyperoxia
regulation of mitophagy
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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