Proteintech

ATL3 Polyclonal Antibody

ATL3 Antibody in Immunocytochemistry (ICC/IF)

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ATL3 Antibody (16921-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using ATL3 antibody 16921-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

ATL3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

16921-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 8 publications 8 publications

Immunocytochemistry (ICC/IF)

1:10-1:100

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ATL3 Fusion Protein Ag10279 (1-351 aa encoded by BC077727)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MLSPQRVAA AASRGADDAM ESSKPGPVQV VLVQKDQHSF ELDEKALASI LLQDHIRDLD VVVVSVAGAF RKGKSFILDF MLRYLYSQKE SGHSNWLGDP EEPLTGFSWR GGSDPETTGI QIWSEVFTVE KPGGKKVAVV LMDTQGAFDS QSTVKDCATI FALSTMTSSV QIYNLSQNIQ EDDLQQLQLF TEYGRLAMDE IFQKPFQTLM FLVRDWSFPY EYSYGLQGGM AFLDKRLQVK EHQHEEIQNV RNHIHSCFSD VTCFLLPHPG LQVATSPDFD GKLKDIAGEF KEQLQALIPY VLNPSKLMEK EINGSKVTCR GLLEYFKAYI KIYQGEDLPH PKSMLQATAE AN (1-351 aa encoded by BC077727)

Target Information

ATL3 is GTPase tethering membranes through formation of trans-homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. ATL3 is function in endoplasmic reticulum tubular network biogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Profiling of purified autophagic vesicle degradome in the maturing and aging brain.

Neuron

Kallergi E,Siva Sankar D,Matera A,Kolaxi A,Paolicelli RC,Dengjel J,Nikoletopoulou V

Wed Aug 02 00:00:00 UTC 2023

Localization of Kif1c mRNA to cell protrusions dictates binding partner specificity of the encoded protein.

Genes & development

Norris ML,Mendell JT

Wed Mar 01 00:00:00 UTC 2023

Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.

Nature

Foronda H,Fu Y,Covarrubias-Pinto A,Bocker HT,González A,Seemann E,Franzka P,Bock A,Bhaskara RM,Liebmann L,Hoffmann ME,Katona I,Koch N,Weis J,Kurth I,Gleeson JG,Reggiori F,Hummer G,Kessels MM,Qualmann B,Mari M,Dikić I,Hübner CA

Thu Jun 01 00:00:00 UTC 2023

Deficiency of Perry syndrome-associated p150^Glued in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.

NPJ Parkinson's disease

Yu J,Yang X,Zheng J,Sgobio C,Sun L,Cai H

Tue Mar 07 00:00:00 UTC 2023

ER proteins decipher the tubulin code to regulate organelle distribution.

Nature

Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C

Sat Jan 01 00:00:00 UTC 2022

ER proteins decipher the tubulin code to regulate organelle distribution.

Nature

Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C

Sat Jan 01 00:00:00 UTC 2022

ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.

Current biology : CB

Chen Q,Xiao Y,Chai P,Zheng P,Teng J,Chen J

Mon Mar 04 00:00:00 UTC 2019

ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.

Current biology : CB

Chen Q,Xiao Y,Chai P,Zheng P,Teng J,Chen J

Mon Mar 04 00:00:00 UTC 2019

ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.

Current biology : CB

Chen Q,Xiao Y,Chai P,Zheng P,Teng J,Chen J

Mon Mar 04 00:00:00 UTC 2019

ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.

Current biology : CB

Chen Q,Xiao Y,Chai P,Zheng P,Teng J,Chen J

Mon Mar 04 00:00:00 UTC 2019

Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites.

Nature communications

Alenquer M,Vale-Costa S,Etibor TA,Ferreira F,Sousa AL,Amorim MJ

Tue Apr 09 00:00:00 UTC 2019

DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.

Cell research

Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J

Wed Aug 01 00:00:00 UTC 2018

DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.

Cell research

Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J

Wed Aug 01 00:00:00 UTC 2018

DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.

Cell research

Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J

Wed Aug 01 00:00:00 UTC 2018

Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology.

eLife

Pawar S,Ungricht R,Tiefenboeck P,Leroux JC,Kutay U

Mon Aug 14 00:00:00 UTC 2017

Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology.

eLife

Pawar S,Ungricht R,Tiefenboeck P,Leroux JC,Kutay U

Mon Aug 14 00:00:00 UTC 2017

Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology.

eLife

Pawar S,Ungricht R,Tiefenboeck P,Leroux JC,Kutay U

Mon Aug 14 00:00:00 UTC 2017

Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology.

eLife

Pawar S,Ungricht R,Tiefenboeck P,Leroux JC,Kutay U

Mon Aug 14 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: atlastin 3; Atlastin-3

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Gene Aliases: 4633402C03Rik; 5730596K20Rik; AI465397; ATL3; AW228836; HSN1F; RGD1309871

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UniProt ID: (Human) Q6DD88, (Rat) Q0ZHH6, (Mouse) Q91YH5

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Entrez Gene ID: (Human) 25923, (Rat) 309187, (Mouse) 109168

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Function(s)

GTPase activity GTP binding identical protein binding nucleotide binding hydrolase activity

Process(es)

ER to Golgi vesicle-mediated transport endoplasmic reticulum organization Golgi organization metabolic process protein homooligomerization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ATL3 Polyclonal Antibody

ATL3 Antibody (16921-1-AP) in ICC/IF

Product Details

16921-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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