Product References
Functional, Morphological and Molecular Changes Reveal the Mechanisms Associated with Age-Related Vestibular Loss.
Biomolecules
Paplou VG,Schubert NMA,van Tuinen M,Vijayakumar S,Pyott SJ
MA3-915 was used in Immunohistochemistry to suggest that age-related vestibular hypofunction is linked to diminished peripheral vestibular responses, likely due to the loss of a specific subpopulation of hair cells and calyceal afferents.
Thu Sep 21 00:00:00 UTC 2023
Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain.
Journal of extracellular vesicles
You Y,Muraoka S,Jedrychowski MP,Hu J,McQuade AK,Young-Pearse T,Aslebagh R,Shaffer SA,Gygi SP,Blurton-Jones M,Poon WW,Ikezu T
MA3-915 was used in Western Blotting to identify cell type-specific extracellular vesicle (EV) protein markers in human-induced pluripotent stem cell-derived neural cell types, including excitatory neurons (ATP1A3, NCAM1), astrocytes (LRP1, ITGA6), microglia-like cells (ITGAM, LCP1), and oligodendrocyte-like cells (LAMP2, FTH1), along with 16 pan-EV marker candidates.
Sat Jan 01 00:00:00 UTC 2022
PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes.
Cells
Tuomainen T,Naumenko N,Mutikainen M,Shakirzyanova A,Sczelecki S,Estall JL,Ruas JL,Tavi P
MA3-915 was used in Western Blotting to highlight the biological roles of the different PGC-1α isoforms, which should be considered when future therapies are developed.
Tue Sep 20 00:00:00 UTC 2022
Na+/K+‑ATPase subunit α3 expression is associated with the efficacy of digitoxin treatment in pancreatic cancer cells.
Medicine international
Lindholm H,Ejeskär K,Szekeres F
MA3-915 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to investigate the effects of digitoxin in relation to the expression of the subunits ATP1A1 and ATP1A3 using three pancreatic cancer cell lines AsPC-1, Panc-1 and CFPAC-1.
Thu Feb 02 00:00:00 UTC 2023
Disposition of Proteins and Lipids in Synaptic Membrane Compartments Is Altered in Q175/Q7 Huntington's Disease Mouse Striatum.
Frontiers in synaptic neuroscience
Iuliano M,Seeley C,Sapp E,Jones EL,Martin C,Li X,DiFiglia M,Kegel-Gleason KB
Published figure using ATP1A3 monoclonal antibody (Product # MA3-915) in Western Blot
Sun Mar 31 00:00:00 UTC 2024
An interaction between PRRT2 and Na+/K+ ATPase contributes to the control of neuronal excitability.
Cell death & disease
Sterlini B,Romei A,Parodi C,Aprile D,Oneto M,Aperia A,Valente P,Valtorta F,Fassio A,Baldelli P,Benfenati F,Corradi A
MA3-915 was used in Immunohistochemistry to demonstrate that PRRT2 is a physiological modulator of NKA function and suggest that an impaired NKA activity contributes to the hyperexcitability phenotype caused by PRRT2 deficiency.
Wed Mar 17 00:00:00 UTC 2021
An interaction between PRRT2 and Na+/K+ ATPase contributes to the control of neuronal excitability.
Cell death & disease
Sterlini B,Romei A,Parodi C,Aprile D,Oneto M,Aperia A,Valente P,Valtorta F,Fassio A,Baldelli P,Benfenati F,Corradi A
MA3-915 was used in Immunohistochemistry to demonstrate that PRRT2 is a physiological modulator of NKA function and suggest that an impaired NKA activity contributes to the hyperexcitability phenotype caused by PRRT2 deficiency.
Wed Mar 17 00:00:00 UTC 2021
An interaction between PRRT2 and Na+/K+ ATPase contributes to the control of neuronal excitability.
Cell death & disease
Sterlini B,Romei A,Parodi C,Aprile D,Oneto M,Aperia A,Valente P,Valtorta F,Fassio A,Baldelli P,Benfenati F,Corradi A
MA3-915 was used in Immunohistochemistry to demonstrate that PRRT2 is a physiological modulator of NKA function and suggest that an impaired NKA activity contributes to the hyperexcitability phenotype caused by PRRT2 deficiency.
Wed Mar 17 00:00:00 UTC 2021
The cellular prion protein interacts with and promotes the activity of Na,K-ATPases.
PloS one
Williams D,Mehrabian M,Arshad H,Eid S,Sackmann C,Zhao W,Wang X,Ghodrati F,Verkuyl CE,Watts JC,Schmitt-Ulms G
Published figure using ATP1A3 monoclonal antibody (Product # MA3-915) in Western Blot
Tue Dec 21 00:00:00 UTC 2021
Evaluation of the Efficacy of Dexamethasone-Eluting Electrode Array on the Post-Implant Cochlear Fibrotic Reaction by Three-Dimensional Immunofluorescence Analysis in Mongolian Gerbil Cochlea.
Journal of clinical medicine
Toulemonde P,Risoud M,Lemesre PE,Beck C,Wattelet J,Tardivel M,Siepmann J,Vincent C
MA3-915 was used in Immunohistochemistry to propose that the cochlear implant used as a corticosteroid delivery system appears to be an encouraging device for the protection of the inner ear against fibrosis induced by implantation.
Wed Jul 28 00:00:00 UTC 2021
Neuronal development in the cochlea of a nonhuman primate model, the common marmoset.
Developmental neurobiology
Hosoya M,Fujioka M,Murayama AY,Ozawa H,Okano H,Ogawa K
MA3-915 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to reveal similarities and differences between previously reported rodent models and a marmoset animal model.
Mon Nov 01 00:00:00 UTC 2021
Differential Membrane Binding and Seeding of Distinct α-Synuclein Fibrillar Polymorphs.
Biophysical journal
Shrivastava AN,Bousset L,Renner M,Redeker V,Savistchenko J,Triller A,Melki R
MA3-915 was used in Immunohistochemistry-immunofluorescence to establish a molecular basis for observing.
Tue Mar 24 00:00:00 UTC 2020
Resistance training upregulates skeletal muscle Na+, K+-ATPase content, with elevations in both α1 and α2, but not β isoforms.
European journal of applied physiology
Altarawneh MM,Petersen AC,Farr T,Garnham A,Broatch JR,Halson S,Bishop DJ,McKenna MJ
MA3-915 was used in Western Blot to investigate the effects of resistance training in healthy young adults on the adaptability of NKA content and of the specific α and β isoforms in human skeletal muscle.
Sat Aug 01 00:00:00 UTC 2020
Effects of testosterone suppression, hindlimb immobilization, and recovery on [3H]ouabain binding site content and Na+, K+-ATPase isoforms in rat soleus muscle.
Journal of applied physiology (Bethesda, Md. : 1985)
Altarawneh MM,Hanson ED,Betik AC,Petersen AC,Hayes A,McKenna MJ
MA3-915 was used in Western Blotting to investigated the effects of testosterone suppression, hindlimb immobilization, and recovery on skeletal muscle Na+,K+-ATPase (NKA), measured via [3H]ouabain binding site content (OB) and NKA isoform abundances (α1-3, β1-2).
Sun Mar 01 00:00:00 UTC 2020
Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway.
Nature communications
Smith SE,Chen X,Brier LM,Bumstead JR,Rensing NR,Ringel AE,Shin H,Oldenborg A,Crowley JR,Bice AR,Dikranian K,Ippolito JE,Haigis MC,Papouin T,Zhao G,Wong M,Culver JP,Bonni A
MA3-915 was used in Western Blotting to show episodic paralysis can be induced in mice with ion pump α2-Na/K ATPase deletion.
Wed Dec 02 00:00:00 UTC 2020
Identification of the retinoschisin-binding site on the retinal Na/K-ATPase.
PloS one
Plössl K,Straub K,Schmid V,Strunz F,Wild J,Merkl R,Weber BHF,Friedrich U
MA3-915 was used in Western Blotting to describe the reinoschisin binding domains in ATP1B2.
Tue Jan 14 00:00:00 UTC 2020
Characterization of transgenic mouse lines for labeling type I and type II afferent neurons in the cochlea.
Scientific reports
Vyas P,Wu JS,Jimenez A,Glowatzki E,Fuchs PA
MA3-915 was used in Immunohistochemistry-immunofluorescence to characterise transgenic mouse lines for labelling type I and type II afferent neurons in the cochlea.
Wed Apr 03 00:00:00 UTC 2019
Differential Expression of Ca2+-buffering Protein Calretinin in Cochlear Afferent Fibers: A Possible Link to Vulnerability to Traumatic Noise.
Experimental neurobiology
Sharma K,Seo YW,Yi E
MA3-915 was used in Immunohistochemistry-immunofluorescence to investigate whether the expression of neuroprotective Ca2+-buffering proteins is spatially segregated in cochlear afferent fibres.
Mon Oct 01 00:00:00 UTC 2018
Differential Expression of Ca2+-buffering Protein Calretinin in Cochlear Afferent Fibers: A Possible Link to Vulnerability to Traumatic Noise.
Experimental neurobiology
Sharma K,Seo YW,Yi E
MA3-915 was used in Immunohistochemistry-immunofluorescence to investigate whether the expression of neuroprotective Ca2+-buffering proteins is spatially segregated in cochlear afferent fibres.
Mon Oct 01 00:00:00 UTC 2018
Proteomic Analysis of Dendritic Filopodia-Rich Fraction Isolated by Telencephalin and Vitronectin Interaction.
Frontiers in synaptic neuroscience
Furutani Y,Yoshihara Y
MA3-915 was used in Immunocytochemistry-immunoflourescence to examine the molecular constituents of dendritic filopodia.
Wed Sep 30 00:00:00 UTC 2020
Regulation of Neuronal Na,K-ATPase by Extracellular Scaffolding Proteins.
International journal of molecular sciences
Liebmann T,Fritz N,Kruusmägi M,Westin L,Bernhem K,Bondar A,Aperia A,Brismar H
MA3-915 was used in Immunocytochemistry-immunoflourescence to study the regulation of neuronal Na,K-ATPase by extracellular scaffolding proteins.
Sun Jul 29 00:00:00 UTC 2018
Cold-water immersion after training sessions: effects on fiber type-specific adaptations in muscle K+ transport proteins to sprint-interval training in men.
Journal of applied physiology (Bethesda, Md. : 1985)
Christiansen D,Bishop DJ,Broatch JR,Bangsbo J,McKenna MJ,Murphy RM
MA3-915 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to show that cold-water immersion (CWI) can be performed regularly without impairing training-induced adaptations at the fiber-type level important for muscle K+ handling.
Wed Aug 01 00:00:00 UTC 2018
Opposing expression gradients of calcitonin-related polypeptide alpha (Calca/Cgrpα) and tyrosine hydroxylase (Th) in type II afferent neurons of the mouse cochlea.
The Journal of comparative neurology
Wu JS,Vyas P,Glowatzki E,Fuchs PA
MA3-915 was used in Immunohistochemistry to compare the expression patterns among cochlear type II afferents of two genes found in C-fibers: calcitonin-related polypeptide alpha (Calca/Cgrpα), specific to pain-sensing C-fibers, and tyrosine hydroxylase (Th), specific to low-threshold mechanoreceptive C-fibers, which was shown previously to be a selective biomarker of type II versus type I cochlear afferents (Vyas et al., ).
Thu Feb 15 00:00:00 UTC 2018
Retinoschisin is linked to retinal Na/K-ATPase signaling and localization.
Molecular biology of the cell
Plössl K,Royer M,Bernklau S,Tavraz NN,Friedrich T,Wild J,Weber BHF,Friedrich U
MA3-915 was used in Immunohistochemistry-immunofluorescence to study the influence of retinoschisin on the functionality of the Na/K-ATPase.
Tue Aug 01 00:00:00 UTC 2017
Tyrosine Hydroxylase Expression in Type II Cochlear Afferents in Mice.
Journal of the Association for Research in Otolaryngology : JARO
Vyas P,Wu JS,Zimmerman A,Fuchs P,Glowatzki E
MA3915 was used in immunohistochemistry to test if tyrosine hydroxylase-driven Cre recombinase can be used to identify type II afferents
Wed Feb 01 00:00:00 UTC 2017
Gestation changes sodium pump isoform expression, leading to changes in ouabain sensitivity, contractility, and intracellular calcium in rat uterus.
Physiological reports
Floyd RV,Mobasheri A,Wray S
MA3-915 was used in Western Blotting to show that gestation induces specific regulatory changes in expression of Na+ and K+ATPase isoforms which influences contractility in rat uterus.
Fri Dec 01 00:00:00 UTC 2017
Characterization of Fatty Acid Binding Protein 7 (FABP7) in the Murine Retina.
Investigative ophthalmology & visual science
Su X,Tan QS,Parikh BH,Tan A,Mehta MN,Sia Wey Y,Tun SB,Li LJ,Han XY,Wong TY,Hunziker W,Luu CD,Owada Y,Barathi VA,Zhang SS,Chaurasia SS
MA3-915 was used in immunohistochemistry - frozen section to elucidate fatty acid binding protein 7 (FABP7) found in the retina of murine mammals
Wed Jun 01 00:00:00 UTC 2016
Cell specific differences in the protein abundances of GAPDH and Na(+),K(+)-ATPase in skeletal muscle from aged individuals.
Experimental gerontology
Wyckelsma VL,McKenna MJ,Levinger I,Petersen AC,Lamboley CR,Murphy RM
MA3-915 was used in western blot to determine cell differences in skeletal muscle from aged individuals regardidng protein abundances of GAPDH and NA,K-ATPase
Tue Mar 01 00:00:00 UTC 2016
Sodium pump organization in dendritic spines.
Neurophotonics
Blom H,Bernhem K,Brismar H
MA3-915 was used in immunocytochemistry to characterize the organization of sodium pumps in dendritic spines
Sat Oct 01 00:00:00 UTC 2016
Sodium pump organization in dendritic spines.
Neurophotonics
Blom H,Bernhem K,Brismar H
MA3-915 was used in immunocytochemistry to characterize the organization of sodium pumps in dendritic spines
Sat Oct 01 00:00:00 UTC 2016
Dissociation between short-term unloading and resistance training effects on skeletal muscle Na+,K+-ATPase, muscle function, and fatigue in humans.
Journal of applied physiology (Bethesda, Md. : 1985)
Perry BD,Wyckelsma VL,Murphy RM,Steward CH,Anderson M,Levinger I,Petersen AC,McKenna MJ
MA3915 was used in western blot to investigate the effects of unilateral lower limb suspension and subsequent resistance training on muscle function and NKA
Tue Nov 01 00:00:00 UTC 2016
Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.
Traffic (Copenhagen, Denmark)
Laird JG,Pan Y,Modestou M,Yamaguchi DM,Song H,Sokolov M,Baker SA
MA3-915 was used in immunoprecipitation to study Na(+) /K(+) -ATPase trafficking in photoreceptors
Tue Dec 01 00:00:00 UTC 2015
Functional Interaction Between Na/K-ATPase and NMDA Receptor in Cerebellar Neurons.
Molecular neurobiology
Akkuratov EE,Lopacheva OM,Kruusmägi M,Lopachev AV,Shah ZA,Boldyrev AA,Liu L
MA3-915 was used in immunocytochemistry and western blot to study the relationship between Na/K-ATPase and NMDA receptor in cerebellar neurons
Tue Dec 01 00:00:00 UTC 2015
Ouabain-Induced Signaling and Cell Survival in SK-N-SH Neuroblastoma Cells Differentiated by Retinoic Acid.
CNS & neurological disorders drug targets
Akkuratov EE,Wu J,Sowa D,Shah ZA,Liu L
MA3-915 was used in western blot to test if retinoic acid alters ouabain-induced signaling
Mon Sep 26 00:00:00 UTC 2016
The effects of knee injury on skeletal muscle function, Na+, K+-ATPase content, and isoform abundance.
Physiological reports
Perry BD,Levinger P,Morris HG,Petersen AC,Garnham AP,Levinger I,McKenna MJ
MA3-915 was used in western blot to investigate the relationship between skeletal muscle Na(+), K(+)-ATPase (NKA) and knee injury
Sun Feb 01 00:00:00 UTC 2015
Single-fiber expression and fiber-specific adaptability to short-term intense exercise training of Na+-K+-ATPase α- and β-isoforms in human skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985)
Wyckelsma VL,McKenna MJ,Serpiello FR,Lamboley CR,Aughey RJ,Stepto NK,Bishop DJ,Murphy RM
MA3-915 was used in Western Blotting to investigate muscle fiber-type-specific NKA adaptability in eight of these adults following 4-wk repeated-sprint exercise training.
Sun Mar 15 00:00:00 UTC 2015
Numb regulates the polarized delivery of cyclic nucleotide-gated ion channels in rod photoreceptor cilia.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ramamurthy V,Jolicoeur C,Koutroumbas D,Mühlhans J,Le YZ,Hauswirth WW,Giessl A,Cayouette M
Wed Oct 15 00:00:00 UTC 2014
Agonist-dependent and -independent dopamine-1-like receptor signalling differentially regulates downstream effectors.
The FEBS journal
Roosterman D
MA3-915 was used in western blot to assess the impact of constitutive dopamine-1 receptor and dopamine-5 receptor signaling in transiently and stably transfected HEK293T cells
Sat Nov 01 00:00:00 UTC 2014
Regulation and pharmacological blockade of sodium-potassium ATPase: a novel pathway to neuropathy.
Journal of the neurological sciences
Paul D,Soignier RD,Minor L,Tau H,Songu-Mize E,Gould HJ
MA3-915 was used in Western Blotting to find evidence that regulation of Na(+), K(+)-ATPase during major inflammatory disease states is critical for homeostatic protection of primary afferent neurons.
Thu May 15 00:00:00 UTC 2014
Alternative splice isoforms of small conductance calcium-activated SK2 channels differ in molecular interactions and surface levels.
Channels (Austin, Tex.)
Scholl ES,Pirone A,Cox DH,Duncan RK,Jacob MH
MA3-915 was used in western blot to report that SK2 channels co-precipitate with calcium permeant alpha9/10-nicotinic acetylcholine receptors and with alpha-actinin-1
Thu Jan 15 00:00:00 UTC 2015
Distribution of Na,K-ATPase α subunits in rat vestibular sensory epithelia.
Journal of the Association for Research in Otolaryngology : JARO
Schuth O,McLean WJ,Eatock RA,Pyott SJ
MA3-915 was used in western blot to investigate the cellular and subcellular patterns of NKAalpha subunit expression within the sensory epithelia of semicircular canals and the otolith organ
Wed Oct 01 00:00:00 UTC 2014
Regional ion channel gene expression heterogeneity and ventricular fibrillation dynamics in human hearts.
PloS one
Sivagangabalan G,Nazzari H,Bignolais O,Maguy A,Naud P,Farid T,Massé S,Gaborit N,Varro A,Nair K,Backx P,Vigmond E,Nattel S,Demolombe S,Nanthakumar K
MA3-915 was used in western blot to study the relationship between ventricular fibrillation and the regional expression of ion channels in the myopathic heart
Fri Oct 17 00:00:00 UTC 2014
Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Edwards IJ,Bruce G,Lawrenson C,Howe L,Clapcote SJ,Deuchars SA,Deuchars J
MA3-915 was used in immunohistochemistry to study the expression of the alpha-1 and alpha-3 isoforms of the Na(+)/K(+)-ATPase in alpha- and gamma-motoneurons
Wed Jun 12 00:00:00 UTC 2013
Cardiac glycosides block cancer growth through HIF-1α- and NF-κB-mediated Plk1.
Carcinogenesis
Xie CM,Liu XY,Yu S,Cheng CH
MA3-915 was used in Immunocytochemistry-immunoflourescence to study the mechanism by which cardiac glycosides induce mitotic arrest and apoptosis.
Thu Aug 01 00:00:00 UTC 2013
Overexpression of the polycystin-1 C-tail enhances sensitivity of M-1 cells to ouabain.
The Journal of membrane biology
Jansson K,Magenheimer BS,Maser RL,Calvet JP,Blanco G
MA3-915 was used in western blot to study the increased ouabain sensitivity of M-1 cells overexpressing the C-terminal domain of polycystin-1
Mon Jul 01 00:00:00 UTC 2013
A specific and essential role for Na,K-ATPase α3 in neurons co-expressing α1 and α3.
The Journal of biological chemistry
Azarias G,Kruusmägi M,Connor S,Akkuratov EE,Liu XL,Lyons D,Brismar H,Broberger C,Aperia A
MA3-915 was used in immunocytochemistry to study the role of Na,K-ATPase isoform alpha3 in CNS neurons co-expressing the ubiquitous Na,K-ATPase isoform alpha1
Fri Jan 25 00:00:00 UTC 2013
The effects of osteoarthritis and age on skeletal muscle strength, Na+-K+-ATPase content, gene and isoform expression.
Journal of applied physiology (Bethesda, Md. : 1985)
Perry BD,Levinger P,Serpiello FR,Caldow MK,Cameron-Smith D,Bartlett JR,Feller JA,Bergman NR,Levinger I,McKenna MJ
MA3-915 was used in western blot to study how skeletal muscle strength and the expression of Na(+)/K(+)-ATPase isoforms are affected by age and osteoarthritis
Fri Nov 01 00:00:00 UTC 2013
Impaired exercise performance and muscle Na(+),K(+)-pump activity in renal transplantation and haemodialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Petersen AC,Leikis MJ,McMahon LP,Kent AB,Murphy KT,Gong X,McKenna MJ
MA3-915 was used in western blot to investigate the relationship between abnormal skeletal muscle Na+,K+-pumps and impaired exercise performance in hemodialysis patients and renal transplant recipients
Tue May 01 00:00:00 UTC 2012
Attenuation of neonatal ischemic brain damage using a 20-HETE synthesis inhibitor.
Journal of neurochemistry
Yang ZJ,Carter EL,Kibler KK,Kwansa H,Crafa DA,Martin LJ,Roman RJ,Harder DR,Koehler RC
MA3-915 was used in western blot to investigate the effect of 20-hydroxyeicosatetraenoic acid synthesis inhibitor HET0016 on neonatal ischemic brain damage
Sun Apr 01 00:00:00 UTC 2012
Nearest neighbor analysis of dopamine D1 receptors and Na(+)-K(+)-ATPases in dendritic spines dissected by STED microscopy.
Microscopy research and technique
Blom H,Rönnlund D,Scott L,Spicarova Z,Rantanen V,Widengren J,Aperia A,Brismar H
MA3-915 was used in immunocytochemistry to analyze dopamine D1 receptors and sodium/potassium-ATPases in dendritic spines
Wed Feb 01 00:00:00 UTC 2012
Unchanged [3H]ouabain binding site content but reduced Na+-K+ pump α2-protein abundance in skeletal muscle in older adults.
Journal of applied physiology (Bethesda, Md. : 1985)
McKenna MJ,Perry BD,Serpiello FR,Caldow MK,Levinger P,Cameron-Smith D,Levinger I
MA3-915 was used in western blot to study the reduced abundance of the Na(+),K(+) pump alpha2 subunit in aged human skeletal muscle
Thu Nov 01 00:00:00 UTC 2012
In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models.
Journal of neurochemistry
Dunn DE,He DN,Yang P,Johansen M,Newman RA,Lo DC
MA3-915 was used in western blot to study the effect of cardiac glycoside oleandrin from Nerium oleander on brain slice-based strokes
Tue Nov 01 00:00:00 UTC 2011
Changes in Na+, K+-ATPase activity and alpha 3 subunit expression in CNS after administration of Na+, K+-ATPase inhibitors.
Neurochemical research
Bersier MG,Peña C,Arnaiz GR
MA3-915 was used in western blot to investigate the effect of sodium/potassium ATPase inhibitors on synaptosomal membrane Na+, K+-ATPase activity and alpha 3 subunit expression in central nervous system
Tue Feb 01 00:00:00 UTC 2011
Aldosterone increases Na+ -K+ -ATPase activity in skeletal muscle of patients with Conn's syndrome.
Clinical endocrinology
Phakdeekitcharoen B,Kittikanokrat W,Kijkunasathian C,Chatsudthipong V
MA3-915 was used in western blot to investigate the effect of aldosterone on sodium/potassium-ATPase activity
Tue Feb 01 00:00:00 UTC 2011
Spatial distribution of Na+-K+-ATPase in dendritic spines dissected by nanoscale superresolution STED microscopy.
BMC neuroscience
Blom H,Rönnlund D,Scott L,Spicarova Z,Widengren J,Bondar A,Aperia A,Brismar H
MA3-915 was used in immunocytochemistry to investigate the spatial distribution of sodium/potassium-ATPase in dendritic spines
Thu Jan 27 00:00:00 UTC 2011
Spatial distribution of Na+-K+-ATPase in dendritic spines dissected by nanoscale superresolution STED microscopy.
BMC neuroscience
Blom H,Rönnlund D,Scott L,Spicarova Z,Widengren J,Bondar A,Aperia A,Brismar H
MA3-915 was used in immunocytochemistry to investigate the spatial distribution of sodium/potassium-ATPase in dendritic spines
Thu Jan 27 00:00:00 UTC 2011
Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.
PLoS genetics
Leo L,Gherardini L,Barone V,De Fusco M,Pietrobon D,Pizzorusso T,Casari G
MA3-915 was used in western blot to investigate the cortical spreading depression in familial hemiplegic migraine type 2 mouse model
Wed Jun 01 00:00:00 UTC 2011
Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.
PLoS genetics
Leo L,Gherardini L,Barone V,De Fusco M,Pietrobon D,Pizzorusso T,Casari G
MA3-915 was used in western blot to investigate the cortical spreading depression in familial hemiplegic migraine type 2 mouse model
Wed Jun 01 00:00:00 UTC 2011
Alterations of Na+/K+-ATPase function in caveolin-1 knockout cardiac fibroblasts.
Journal of molecular and cellular cardiology
Quintas LE,Pierre SV,Liu L,Bai Y,Liu X,Xie ZJ
MA3-915 was used in western blot to investigate the role of caveolin in the function of sodium potassium ATPase in mice
Wed Sep 01 00:00:00 UTC 2010
Increase in ouabain-sensitive K+-ATPase activity in hepatocellular carcinoma by overexpression of Na+, K+-ATPase alpha 3-isoform.
European journal of pharmacology
Shibuya K,Fukuoka J,Fujii T,Shimoda E,Shimizu T,Sakai H,Tsukada K
MA3-915 was used in western blot to investigate the effect of alpha 3NaK overexpression on sodium/potassium ATPase activity of hepatocellular carcinoma cells
Sun Jul 25 00:00:00 UTC 2010
The ouabain-binding site of the α2 isoform of Na,K-ATPase plays a role in blood pressure regulation during pregnancy.
American journal of hypertension
Oshiro N,Dostanic-Larson I,Neumann JC,Lingrel JB
MA3-915 was used in western blot to investigate the role alpha2 sodium/potassium-ATPase domains on blood pressure
Wed Dec 01 00:00:00 UTC 2010
BK channels mediate cholinergic inhibition of high frequency cochlear hair cells.
PloS one
Wersinger E,McLean WJ,Fuchs PA,Pyott SJ
MA3-915 was used in immunohistochemistry to investigate the role of BK channel in the regulation of cochlear hair cell function
Thu Nov 04 00:00:00 UTC 2010
Ca2+ influx mechanisms in caveolae vesicles of pulmonary smooth muscle plasma membrane under inhibition of alpha2beta1 isozyme of Na+/K+-ATPase by ouabain.
Life sciences
Ghosh B,Kar P,Mandal A,Dey K,Chakraborti T,Chakraborti S
MA3-915 was used in western blot to study the role of sodium/potassium ATPase alpha2beta1 in calcium homeostasis in caveolae vesicles
Fri Jan 30 00:00:00 UTC 2009
Distribution of the Na,K-ATPase alpha subunit in the rat spiral ganglion and organ of corti.
Journal of the Association for Research in Otolaryngology : JARO
McLean WJ,Smith KA,Glowatzki E,Pyott SJ
MA3-915 was used in immunohistochemistry to study the neuronal distribution of Na,K-ATPase alpha subunit in the spiral ganglion and organ of Corti
Sun Mar 01 00:00:00 UTC 2009
Enhanced pressor response to increased CSF sodium concentration and to central ANG I in heterozygous alpha2 Na+ -K+ -ATPase knockout mice.
American journal of physiology. Regulatory, integrative and comparative physiology
Hou X,Theriault SF,Dostanic-Larson I,Moseley AE,Lingrel JB,Wu H,Dean S,Van Huysse JW
MA3-915 was used in western blot to study the effect of ouabain-like substance on the expression of sodium-potassium-ATPase isoforms.
Fri May 01 00:00:00 UTC 2009
Over-expression of translationally controlled tumor protein in lens epithelial cells seems to be associated with cataract development.
Transgenic research
Kim MJ,Lyu J,Sohn KB,Kim M,Cho MC,Joo CK,Lee K
MA3-915 was used in western blot to investigate the relationship between translationally controlled tumor protein expression in lens epithelial cells and cataract development
Tue Dec 01 00:00:00 UTC 2009
Modulation of endothelial cell KCa3.1 channels during endothelium-derived hyperpolarizing factor signaling in mesenteric resistance arteries.
Circulation research
Dora KA,Gallagher NT,McNeish A,Garland CJ
MA3-915 was used in Immunohistochemistry to study how K(+) and myoendothelial coupling evoke EDHF-mediated relaxation through distinct, definable pathways.
Fri May 23 00:00:00 UTC 2008
Ouabain binds with high affinity to the Na,K-ATPase in human polycystic kidney cells and induces extracellular signal-regulated kinase activation and cell proliferation.
Journal of the American Society of Nephrology : JASN
Nguyen AN,Wallace DP,Blanco G
MA3-915 was used in western blot to investigate the effect of ouabain on the cell proliferation and MEK-ERK pathway of human normal and polycystic kidney cells
Mon Jan 01 00:00:00 UTC 2007
Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Moseley AE,Williams MT,Schaefer TL,Bohanan CS,Neumann JC,Behbehani MM,Vorhees CV,Lingrel JB
MA3-915 was used in western blot to study the role of the sodium/potassium ATPase alpha isoform in spatial learning, motor activity, and anxiety in mice.
Wed Jan 17 00:00:00 UTC 2007
Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.
Journal of applied physiology (Bethesda, Md. : 1985)
Aughey RJ,Murphy KT,Clark SA,Garnham AP,Snow RJ,Cameron-Smith D,Hawley JA,McKenna MJ
MA3-915 was used in western blot to demonstrate that the upregulation of sodium/potassium-ATPase alpha mRNA play a role in responding to intense interval exercise and training in athletes
Sun Jul 01 00:00:00 UTC 2007
Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death.
The Journal of comparative neurology
Martin LJ,Liu Z,Chen K,Price AC,Pan Y,Swaby JA,Golden WC
MA3-915 was used in western blot to examine the neuronal cell death in the spinal cords of mSOD1 and wtSOD1 mice
Mon Jan 01 00:00:00 UTC 2007
Effects of congestive heart failure on Ca2+ handling in skeletal muscle during fatigue.
Circulation research
Lunde PK,Sejersted OM,Thorud HM,Tønnessen T,Henriksen UL,Christensen G,Westerblad H,Bruton J
MA3-915 was used in Western Blotting to examine the mechanisms causing soleus fibres in rats with congestive heart failure to fatigue more rapidly than in healthy rats.
Fri Jun 23 00:00:00 UTC 2006
7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: roles of NADPH oxidase, mitochondria, and lipid rafts.
Free radical biology & medicine
Valencia A,Rajadurai A,Carle AB,Kochevar IE
MA3-915 was used in immunocytochemistry to study the mechanism by which 7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes
Fri Dec 01 00:00:00 UTC 2006
The Na,K-ATPase alpha4 isoform from humans has distinct enzymatic properties and is important for sperm motility.
Molecular human reproduction
Sanchez G,Nguyen AN,Timmerberg B,Tash JS,Blanco G
MA3-915 was used in western blot to investigate the expression, localization and function of Na,K-ATPase alpha 4 isoform in human spermatozoa
Fri Sep 01 00:00:00 UTC 2006
Prolonged submaximal exercise induces isoform-specific Na+-K+-ATPase mRNA and protein responses in human skeletal muscle.
American journal of physiology. Regulatory, integrative and comparative physiology
Murphy KT,Petersen AC,Goodman C,Gong X,Leppik JA,Garnham AP,Cameron-Smith D,Snow RJ,McKenna MJ
MA3-915 was used in western blot to study the role of prolonged submaximal exercise on the expression level of sodium/potassium-ATPase mRNA and protein in human skeletal muscle
Wed Feb 01 00:00:00 UTC 2006
Evidence that the H1-H2 domain of alpha1 subunit of (Na++K+)-ATPase participates in the regulation of cardiac contraction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Xu KY,Takimoto E,Juang GJ,Zhang Q,Rohde H,Myers AC
MA3-915 was used in western blot to study the relationship between alpha1 H1-H2 sequence and NKA-contractile modulation
Sat Jan 01 00:00:00 UTC 2005
Calcium adaptation to sodium pump inhibition in a human megakaryocytic cell line.
American journal of physiology. Cell physiology
Kimura M,Cao X,Aviv A
MA3-915 was used in western blot to study the interplay between calcium homeostasis and sodium pump activity in a human megakaryocytic cell line
Sat Oct 01 00:00:00 UTC 2005
Mutations in the Na+/K+ -ATPase alpha3 gene ATP1A3 are associated with rapid-onset dystonia parkinsonism.
Neuron
de Carvalho Aguiar P,Sweadner KJ,Penniston JT,Zaremba J,Liu L,Caton M,Linazasoro G,Borg M,Tijssen MA,Bressman SB,Dobyns WB,Brashear A,Ozelius LJ
MA3-915 was used in western blot to study the association of mutations in the Na+/K+-ATPase alpha 3 subunit with rapid-onset dystonia Parkinsonism
Thu Jul 22 00:00:00 UTC 2004
Intense exercise up-regulates Na+,K+-ATPase isoform mRNA, but not protein expression in human skeletal muscle.
The Journal of physiology
Murphy KT,Snow RJ,Petersen AC,Murphy RM,Mollica J,Lee JS,Garnham AP,Aughey RJ,Leppik JA,Medved I,Cameron-Smith D,McKenna MJ
MA3-915 was used in western blot to investigate the effect of acute exercise effects on sodium/potassium-ATPase isoform expression in human skeletal muscle.
Thu Apr 15 00:00:00 UTC 2004
The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.
American journal of physiology. Cell physiology
Radzyukevich TL,Moseley AE,Shelly DA,Redden GA,Behbehani MM,Lingrel JB,Paul RJ,Heiny JA
MA3-915 was used in western blot to study the role of the sodium/potassium-ATPase alpha2-subunit isoform during muscle contraction
Mon Nov 01 00:00:00 UTC 2004
Na(+) pump alpha 2-isoform specifically couples to contractility in vascular smooth muscle: evidence from gene-targeted neonatal mice.
American journal of physiology. Cell physiology
Shelly DA,He S,Moseley A,Weber C,Stegemeyer M,Lynch RM,Lingrel J,Paul RJ
MA3-915 was used in western blot to investigate the importance of various sodium-pump isoforms in vascular function
Thu Apr 01 00:00:00 UTC 2004
The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart.
The Journal of biological chemistry
Dostanic I,Schultz Jel J,Lorenz JN,Lingrel JB
MA3-915 was used in western blot to study the role of the sodium potassium ATPase alpha 1 isoform in heart.
Fri Dec 24 00:00:00 UTC 2004
The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart.
The Journal of biological chemistry
Dostanic I,Schultz Jel J,Lorenz JN,Lingrel JB
MA3-915 was used in western blot to study the role of the sodium potassium ATPase alpha 1 isoform in heart.
Fri Dec 24 00:00:00 UTC 2004
Quantification of alpha-subunit isoforms of Na,K-ATPase in rat resistance vessels.
Acta physiologica Scandinavica
Hansen O
MA3-915 was used in western blot to investigate the expression level of sodium/potassium ATPase alpha-subunit isoforms in rat resistance vessels
Thu Jan 01 00:00:00 UTC 2004
Phospholemman expression in extraglomerular mesangium and afferent arteriole of the juxtaglomerular apparatus.
American journal of physiology. Renal physiology
Wetzel RK,Sweadner KJ
MA3-915 was used in immunohistochemistry to study the expression of phospholemman in the juxtaglomerular apparatus
Tue Jul 01 00:00:00 UTC 2003
Stretch receptor-associated expression of alpha 3 isoform of the Na+, K+-ATPase in rat peripheral nervous system.
Neuroscience
Dobretsov M,Hastings SL,Sims TJ,Stimers JR,Romanovsky D
MA3-915 was used in immunohistochemistry to investigate the expression of the alpha3 isoform of the Na+,K+ -ATPase in rat peripheral nervous system
Wed Apr 30 00:00:00 UTC 2003
The alpha2 isoform of Na,K-ATPase mediates ouabain-induced cardiac inotropy in mice.
The Journal of biological chemistry
Dostanic I,Lorenz JN,Schultz Jel J,Grupp IL,Neumann JC,Wani MA,Lingrel JB
MA3-915 was used in western blot to study the effect of sodium/potassium ATPase on ouabain-induced cardiac contractility in mice.
Fri Dec 26 00:00:00 UTC 2003
The alpha2 isoform of Na,K-ATPase mediates ouabain-induced cardiac inotropy in mice.
The Journal of biological chemistry
Dostanic I,Lorenz JN,Schultz Jel J,Grupp IL,Neumann JC,Wani MA,Lingrel JB
MA3-915 was used in western blot to study the effect of sodium/potassium ATPase on ouabain-induced cardiac contractility in mice.
Fri Dec 26 00:00:00 UTC 2003
The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.
The Journal of biological chemistry
Moseley AE,Lieske SP,Wetzel RK,James PF,He S,Shelly DA,Paul RJ,Boivin GP,Witte DP,Ramirez JM,Sweadner KJ,Lingrel JB
MA3-915 was used in western blot to investigate the role of Na,K-ATPase alpha 2 isoform in the modulation of neuronal activity in the neonate
Fri Feb 14 00:00:00 UTC 2003
Na pump isoforms in human erythroid progenitor cells and mature erythrocytes.
Proceedings of the National Academy of Sciences of the United States of America
Hoffman JF,Wickrema A,Potapova O,Milanick M,Yingst DR
Published figure using ATP1A3 monoclonal antibody (Product # MA3-915) in Western Blot
Tue Oct 29 00:00:00 UTC 2002
Phorbol diacetate potentiates na(+)-k(+) ATPase inhibition by a putative endogenous ligand, marinobufagenin.
Hypertension (Dallas, Tex. : 1979)
Fedorova OV,Dorofeeva NA,Lopatin DA,Lakatta EG,Bagrov AY
MA3-915 was used in western blot to investigate the effects of PKC-induced-specific NKA isoform phosphorylation on NKA inhibition and vasoconstriction
Fri Feb 01 00:00:00 UTC 2002
The influence of cycloheximide on Na,K-ATPase activity in cultured human lens epithelial cells.
Investigative ophthalmology & visual science
Cui G,Dean WL,Delamere NA
MA3-915 was used in western blot to investigate the effect of cycloheximide on sodium/potassium ATPase activity.
Thu Aug 01 00:00:00 UTC 2002
Altered Na,K-ATPase pattern in gamma-crystallin mutant mice.
Investigative ophthalmology & visual science
Moseley A,Graw J,Delamere NA
MA3-915 was used in western blot to investigate the differences of the sodium/potassium ATPase subunits alpha1, alpha2, and alpha3 in both mutant and wild-type mice.
Wed May 01 00:00:00 UTC 2002
Ubiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1).
The Journal of biological chemistry
Brickley DR,Mikosz CA,Hagan CR,Conzen SD
MA3-915 was used in immunocytochemistry to investigate the localization and ubiquitination status of serum and glucocorticoid-induced protein kinase-1.
Fri Nov 08 00:00:00 UTC 2002
The alpha(1)- and alpha(2)-isoforms of Na-K-ATPase play different roles in skeletal muscle contractility.
American journal of physiology. Regulatory, integrative and comparative physiology
He S,Shelly DA,Moseley AE,James PF,James JH,Paul RJ,Lingrel JB
MA3-915 was used in western blot to investigate sodium/potassium-ATPase alpha 1- and alpha 2-isoforms' specific functional properties
Sat Sep 01 00:00:00 UTC 2001
Endogenous Na,K pump ligands are differentially regulated during acute NaCl loading of Dahl rats.
Circulation
Fedorova OV,Lakatta EG,Bagrov AY
MA3-915 was used in western blot to investigate the effect of acute NaCl loading on MBG and OLC in Dahl salt-sensitive (DS) and salt-resistant (DR) rats
Tue Dec 12 00:00:00 UTC 2000
Identification of a specific role for the Na,K-ATPase alpha 2 isoform as a regulator of calcium in the heart.
Molecular cell
James PF,Grupp IL,Grupp G,Woo AL,Askew GR,Croyle ML,Walsh RA,Lingrel JB
MA3-915 was used in western blot to study the role of the sodium/potassium ATPase alpha-2 in calcium signaling during cardiac contraction
Sat May 01 00:00:00 UTC 1999
Regulation of Na+ pump function by aldosterone is alpha-subunit isoform specific.
The Journal of physiology
Pfeiffer R,Beron J,Verrey F
MA3-915 was used in western blot to investigate the role of the aldosterone during the activation of sodium pumps
Sat May 01 00:00:00 UTC 1999
Heterogeneity of Na+/K+-ATPase from rectal gland of Squalus acanthias is not due to alpha isoform diversity.
Pflugers Archiv : European journal of physiology
Hansen O
MA3-915 was used in western blot to characterize the sodium/potassium ATPase from rectal glands of squalus acanthias
Mon Mar 01 00:00:00 UTC 1999
Isoforms of Na,K-ATPase alpha and beta subunits in the rat cerebellum and in granule cell cultures.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Peng L,Martin-Vasallo P,Sweadner KJ
MA3-915 was used in immunohistochemistry to investigate the distribution of sodium/potent ATPase isoforms in the rat cerebellum and granule cell cultures
Thu May 15 00:00:00 UTC 1997
Isoform-specific monoclonal antibodies to Na,K-ATPase alpha subunits. Evidence for a tissue-specific post-translational modification of the alpha subunit.
The Journal of biological chemistry
Arystarkhova E,Sweadner KJ
MA3-915 was used in western blot to characterize Na,K-ATPase alpha monoclonal antibodies
Fri Sep 20 00:00:00 UTC 1996
