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Invitrogen
ATP6V1B2 Polyclonal Antibody
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ATP6V1B2 Antibody (PA5-77872) in IHC (P)
ATP6V1B2 Polyclonal Antibody detects ATP6V1B2 protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. ATP6V1B2 Polyclonal Antibody (Product # PA5-77872) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-77872
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human ATP6V1B2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.0 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735504
Product Specific Information
Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, Mouse brain, Rat brain
Predicted Reactivity: Zebrafish (96%), Xenopus laevis (97%), Chicken (99%), Chimpanzee (99%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ATP6V1B2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa, isoform 2; ATPase, H+ transporting, lysosomal 56/58kD, V1 subunit B, isoform 2; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2; ATPase, H+ transporting, V1 subunit B, isoform 2; Endomembrane proton pump 58 kDa subunit; H+ transporting two-sector ATPase; HO57; lysosomal 56/58kDa; testicular secretory protein Li 65; V-ATPase B2 subunit; V-ATPase subunit B 2; V-type proton ATPase subunit B, brain isoform; vacuolar H+-ATPase 56,000 subunit; vacuolar H+ATPase B2; Vacuolar proton pump subunit B 2
Gene Aliases: AI194269; AI790362; ATP6B1B2; ATP6B2; ATP6V1B2; DOOD; HO57; R74844; Vat2; VATB; Vma2; VPP3; ZLS2
UniProt ID: (Human) P21281, (Mouse) P62814, (Rat) P62815
Entrez Gene ID: (Human) 526, (Mouse) 11966, (Rat) 117596
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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