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Invitrogen
ATXN1L Polyclonal Antibody
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Product Details
PA5-66506
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human ATXN1L. Recombinant protein control fragment (Product #RP-107176).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2662504
Product Specific Information
Immunogen sequence: AHSFNKAPSAT SPSGQLPHHS STQPLDLAPG RMPIYYQMSR LPAGYTLHET PPAGASPVLT PQESQS
Highest antigen sequence identity to the following orthologs - mouse 87%, rat 84%.
Target Information
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (PubMed:21475249). Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1). In concert with CIC and ATXN1, involved in brain development. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ataxin 1-like; Ataxin-1-like; Brother of ataxin-1; Brother of ATXN1
Gene Aliases: ATXN1L; BOAT; BOAT1
UniProt ID: (Human) P0C7T5
Entrez Gene ID: (Human) 342371
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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