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Invitrogen
AZGP1 Polyclonal Antibody
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FIGURE: 1 / 1
AZGP1 Antibody (PA5-120907) in WB
Western blot analysis of AZGP1 in extracts of Human serum. Samples were incubated with AZGP1 Polyclonal antibody (Product # PA5-120907) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-120907
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 21-298 of human Zinc-α2-glycoprotein (ZAG/Zinc-α2-glycoprotein (ZAG/AZGP1)) (NP_0011761)
Conjugate
Form
Liquid
Concentration
0.52 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2914479
Product Specific Information
Positive test controls include: Human serum. The target is usually found in the following locations: Secreted.
Immunogen sequence: QENQDGRYSL TYIYTGLSKH VEDVPAFQAL GSLNDLQFFR YNSKDRKSQP MGLWRQVEGM EDWKQDSQLQ KAREDIFMET LKDIVEYYND SNGSHVLQGR FGCEIENNRS SGAFWKYYYD GKDYIEFNKE IPAWVPFDPA AQITKQKWEA EPVYVQRAKA YLEEECPATL RKYLKYSKNI LDRQDPPSVV VTSHQAPGEK KKLKCLAYDF YPGKIDVHWT RAGEVQEPEL RGDVLHNGNG TYQSWVVVAV PPQDTAPYSC HVQHSSLAQP LVVPWEAS
Target Information
Alpha-2-glycoprotein 1, zinc-binding (AZGP1) is a gene encoding a protein that belongs to the immunoglobulin superfamily. This protein is abundant in various body fluids, such as blood plasma and milk, and is involved in lipid mobilization. AZGP1 is expressed in numerous tissues, including the liver, prostate, and adipose tissue, where it plays a significant role in the regulation of lipid metabolism and adipocyte function. It acts as an adipokine, influencing the breakdown and mobilization of fats, thereby contributing to energy homeostasis. In cancer research, AZGP1 has been highlighted for its potential as a prognostic biomarker, particularly in prostate and breast cancer, where lower expression levels are often associated with poor prognosis. Recent studies have also linked AZGP1 to cachexia, an extreme form of weight loss and muscle wasting, by promoting lipid mobilization in adipose tissue and influencing systemic catabolic states. Due to its multifaceted roles in lipid metabolism and disease processes, AZGP1 is considered a promising target for therapeutic interventions in metabolic and cancer-related disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-2-glycoprotein, zinc; major histocompatibility complex class I-like protein; testicular tissue protein Li 227; Zinc a 2 glycoprotein; Zinc a2glycoprotein; Zinc alpha2glycoprotein; Zinc α 2 glycoprotein; Zinc α2glycoprotein; Zinc-alpha-2-glycoprotein; Zn a 2 glycoprotein; Zn a 2 GP; Zn alpha 2 glycoprotein; Zn alpha 2 GP; Zn α 2 glycoprotein; Zn α 2 GP; zn-alpha-2-glycoprotein; Zn-alpha-2-GP; Zn-alpha2-glycoprotein
Gene Aliases: AZGP1; ZA2G; ZAG; ZNGP1
UniProt ID: (Human) P25311, (Mouse) Q64726
Entrez Gene ID: (Human) 563, (Mouse) 12007
detection of chemical stimulus involved in sensory perception of bitter taste
antigen processing and presentation of peptide antigen via MHC class I
immune response
cell adhesion
antigen processing and presentation
regulation of multicellular organism growth
retina homeostasis
negative regulation of cell proliferation
transmembrane transport
protein transmembrane transport
RNA phosphodiester bond hydrolysis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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