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Invitrogen
Actin-like 8 Polyclonal Antibody
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Product Details
PA5-21788
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human ACTL8. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.71 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152106
Product Specific Information
Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Actin-like protein 8 (ACTL8), also known as Cancer/Testis Antigen 57 (CT57), is part of the cancer/testis antigen (CTA) family. It is primarily expressed in the testes but aberrantly overexpressed in various cancers, including lung adenocarcinoma, endometrial cancer, and colorectal cancer. ACTL8's overexpression is associated with enhanced cell mobility, proliferation, and colony formation, contributing to tumor growth and poor prognosis. The gene is believed to play a critical role in oncogenesis and is being investigated as a potential therapeutic target due to its involvement in tumorigenic processes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin like protein; actin-like 8; Actin-like protein 8; Cancer/testis antigen 57; CT57
Gene Aliases: ACTL8; CT57
UniProt ID: (Human) Q9H568
Entrez Gene ID: (Human) 81569
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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