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Invitrogen
Adenylate Cyclase 4 Polyclonal Antibody
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FIGURE: 1 / 3
Adenylate Cyclase 4 Antibody (PA5-101283) in ICC/IF
Immunofluorescent analysis of Adenylate Cyclase 4 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and Adenylate Cyclase 4 polyclonal antibody (Product # PA5-101283) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse... View More
Product Details
PA5-101283
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ADCY4(Accession Q8NFM4), corresponding to amino acid residues D863-L913.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2850722
Product Specific Information
Antibody detects endogenous levels of total ADCY4.
Target Information
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A cyclase IV; Adenylate cyclase type 4; Adenylate cyclase type IV; Adenylyl cyclase 4; ATP pyrophosphate-lyase 4; KIAA4004
Gene Aliases: AC4; ADCY4; mKIAA4004
UniProt ID: (Human) Q8NFM4, (Mouse) Q91WF3
Entrez Gene ID: (Human) 196883, (Rat) 54223, (Mouse) 104110
renal water homeostasis
cAMP biosynthetic process
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
cAMP-mediated signaling
activation of protein kinase A activity
cellular response to glucagon stimulus
intracellular signal transduction
cyclic nucleotide biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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