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Invitrogen
Adenylate Kinase 1 Polyclonal Antibody
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FIGURE: 1 / 2
Adenylate Kinase 1 Antibody (PA5-81582) in WB
Western Blot using Adenylate Kinase 1 Polyclonal Antibody (Product # PA5-81582) at 1:500 dilution. Lane A: Rat Heart tissue lysate, Lane B: Rat Brain tissue lysate. Lysates/proteins at 30 μg per lane. Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1:10,000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 22 kDa. Observed band size: 22 kDa.
Product Details
PA5-81582
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Rat AK1/Adenylate kinase 1 Protein (Met1-Lys194)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2788780
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Rat AK1/Adenylate kinase 1.
Target Information
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenylate kinase isoenzyme 1; adenylate kinase isoenzyme 1 {ECO:0000255|HAMAP-Rule:MF_03171}; Adenylate monophosphate kinase; adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03171}; AK 1; AK 1 {ECO:0000255|HAMAP-Rule:MF_03171}; ATP-AMP transphosphorylase 1; ATP-AMP transphosphorylase 1 {ECO:0000255|HAMAP-Rule:MF_03171}; ATP:AMP phosphotransferase; ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03171}; Myokinase; myokinase {ECO:0000255|HAMAP-Rule:MF_03171}
Gene Aliases: Ak 1; Ak1
UniProt ID: (Rat) P39069
Entrez Gene ID: (Rat) 24183
nucleoside diphosphate phosphorylation
ADP biosynthetic process
cell cycle arrest
muscle organ development
nucleoside triphosphate biosynthetic process
positive regulation of glucose transport
positive regulation of neuron maturation
response to activity
cerebellum development
olfactory bulb development
neuron differentiation
response to estradiol
response to testosterone
response to drug
AMP metabolic process
ATP metabolic process
adenine metabolic process
inosine biosynthetic process
nucleotide phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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