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Invitrogen
Adenylate Kinase 4 Polyclonal Antibody
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FIGURE: 1 / 5
Adenylate Kinase 4 Antibody (PA5-28578) in ICC/IF
Adenylate Kinase 4 Polyclonal Antibody detects Adenylate kinase 4 protein at mitochondria by immunofluorescent analysis. Sample: SKNSH cells were fixed in 2% paraformaldehyde/culture medium at 37oC for 30 min. Green: Adenylate kinase 4 protein stained by Adenylate Kinase 4 Polyclonal Antibody (Product # PA5-28578) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
Product Details
PA5-28578
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Adenylate kinase 4. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2546054
Product Specific Information
Recommended positive controls: HeLa, HepG2, HCT116.
Predicted reactivity: Mouse (88%), Rat (87%), Pig (90%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adenylate kinase 3 alpha-like 1; Adenylate kinase 3-like; adenylate kinase 3-like 1; adenylate kinase 3-like 2; adenylate kinase 3-like {ECO:0000255|HAMAP-Rule:MF_03170}; Adenylate kinase 4, mitochondrial; adenylate kinase 4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03170}; adenylate kinase isoenzyme 4, mitochondrial; AK 4; AK 4 {ECO:0000255|HAMAP-Rule:MF_03170}; AK4; ATP-AMP transphosphorylase; GTP:AMP phosphotransferase AK4; GTP:AMP phosphotransferase AK4 {ECO:0000255|HAMAP-Rule:MF_03170}; GTP:AMP phosphotransferase AK4, mitochondrial; mitochondrial adenylate kinase-3; nucleoside-triphosphate-adenylate kinase; RP4-686B20.1
Gene Aliases: AK 4; Ak-3; Ak-4; AK3; Ak3b; AK3L1; AK3L2; AK4; D4Ertd274e
UniProt ID: (Human) P27144, (Rat) Q9WUS0, (Mouse) Q9WUR9
Entrez Gene ID: (Human) 205, (Rat) 29223, (Mouse) 11639
adenylate kinase activity
nucleoside diphosphate kinase activity
ATP binding
GTP binding
nucleoside triphosphate adenylate kinase activity
nucleoside phosphate kinase activity
molecular_function
nucleotide binding
kinase activity
transferase activity
phosphotransferase activity, phosphate group as acceptor
nucleobase-containing compound kinase activity
liver development
nucleoside diphosphate phosphorylation
ADP biosynthetic process
brain development
nucleoside triphosphate biosynthetic process
nucleobase-containing small molecule interconversion
response to drug
AMP metabolic process
ATP metabolic process
GTP metabolic process
nucleoside monophosphate phosphorylation
nucleobase-containing compound metabolic process
phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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