Invitrogen

Adiponectin Polyclonal Antibody

Adiponectin Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 29

Adiponectin Antibody (PA1-054) in ICC/IF

Immunofluorescence analysis of Adiponectin was performed using 70% confluent 3T3-L1 cells differentiated with StemPro Adipogenesis Supplement (Product # A10070-01) for 5 days. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Adiponectin Rabbit Polyclonal Anti... View More

Adiponectin Antibody in Western Blot (WB)

Adiponectin Antibody in Immunohistochemistry (IHC)

Adiponectin Antibody in Mass Spectrometry (MS)

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Product Details

PA1-054

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

View 36 publications 36 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunocytochemistry (ICC/IF)

2 µg/mL

View 3 publications 3 publications

Immunoprecipitation (IP)

Assay-dependent

Blocking Assay (BLOCK)

View 1 publication 1 publication

Mass Spectrometry (MS)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptides corresponding to the residues E(18) D D V T T T E E L A P A L V(32) and F(187) T Y D Q Y Q E K N V D Q A(200) of mouse Adiponectin.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_325789

Product Specific Information

PA1-054 detects Adiponectin (30 kDa) from mouse serum.

PA1-054 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects an ~30 kDa protein representing Adiponectin from mouse serum.

The PA1-054 immunogen is a pair of synthetic peptides corresponding to the residues E(18) D D V T T T E E L A P A L V(32) and F(187) T Y D Q Y Q E K N V D Q A(200) of mouse Adiponectin.

Target Information

Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates the metabolism of lipids and glucose. Adiponectin has been shown to play a role in various physiological processes including homeostasis and obesity. Decreased levels of adiponectin are associated with obese individuals as well as insulin resistance and hyperinsulinemia (type 2 diabetes). In mice adiponectin has been shown to improve insulin signaling, thus ameliorating insulin resistance. Through activation of AMP kinase and PPAR-alpha, adiponectin can increase fatty acid transport, oxidation, and dissipation in skeletal muscle, leading to a reduction of intramyocellular lipid levels and thus improved insulin signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

PPARγ Acetylation in Adipocytes Exacerbates BAT Whitening and Worsens Age-Associated Metabolic Dysfunction.

Cells

He Y,Zhang R,Yu L,Zahr T,Li X,Kim TW,Qiang L

PA1-054 was used in Western Blot to suggest pathogenic implications of adipocyte PPARγ acetylation, contributing to metabolic dysfunction in aging and thus posing as a potential therapeutic target.

Thu May 18 00:00:00 UTC 2023

PPARγ Acetylation in Adipocytes Exacerbates BAT Whitening and Worsens Age-Associated Metabolic Dysfunction.

Cells

He Y,Zhang R,Yu L,Zahr T,Li X,Kim TW,Qiang L

PA1-054 was used in Western Blot to suggest pathogenic implications of adipocyte PPARγ acetylation, contributing to metabolic dysfunction in aging and thus posing as a potential therapeutic target.

Thu May 18 00:00:00 UTC 2023

PPARγ Acetylation in Adipocytes Exacerbates BAT Whitening and Worsens Age-Associated Metabolic Dysfunction.

Cells

He Y,Zhang R,Yu L,Zahr T,Li X,Kim TW,Qiang L

PA1-054 was used in Western Blot to suggest pathogenic implications of adipocyte PPARγ acetylation, contributing to metabolic dysfunction in aging and thus posing as a potential therapeutic target.

Thu May 18 00:00:00 UTC 2023

Cyclophilin B, a molecule chaperone, promotes adipogenesis in 3T3‑L1 preadipocytes via AKT/mTOR pathway.

International journal of molecular medicine

Yoon JS,Kim SS,Ha J,Kang I,Choe W

PA1-054 was used in Western Blotting to show that CypB levels regulates 3T3-L1 adipocyte differentiation via mTOR signaling pathway.

Sun Jan 01 00:00:00 UTC 2023

Cyclophilin B, a molecule chaperone, promotes adipogenesis in 3T3‑L1 preadipocytes via AKT/mTOR pathway.

International journal of molecular medicine

Yoon JS,Kim SS,Ha J,Kang I,Choe W

PA1-054 was used in Western Blotting to show that CypB levels regulates 3T3-L1 adipocyte differentiation via mTOR signaling pathway.

Sun Jan 01 00:00:00 UTC 2023

Uncoupling Lipid Synthesis from Adipocyte Development.

Biomedicines

Wan Q,Calhoun C,Zahr T,Qiang L

PA1-054 was used in Western Blotting to suggest that lipid synthesis and storage are not the defining features of adipocytes and raise the possibility of uncoupling lipid synthesis from adipocyte development to achieve smaller and healthier adipocytes for the treatment of obesity and related disorders.

Sun Apr 09 00:00:00 UTC 2023

Adipose mTORC2 is essential for sensory innervation in white adipose tissue and whole-body energy homeostasis.

Molecular metabolism

Frei IC,Weissenberger D,Ritz D,Heusermann W,Colombi M,Shimobayashi M,Hall MN

PA1-054 was used in Immunohistochemistry to indicate that adipose mTORC2 is necessary for sensory innervation in white adipose tissue.

Tue Nov 01 00:00:00 UTC 2022

Adipose mTORC2 is essential for sensory innervation in white adipose tissue and whole-body energy homeostasis.

Molecular metabolism

Frei IC,Weissenberger D,Ritz D,Heusermann W,Colombi M,Shimobayashi M,Hall MN

PA1-054 was used in Immunohistochemistry to indicate that adipose mTORC2 is necessary for sensory innervation in white adipose tissue.

Tue Nov 01 00:00:00 UTC 2022

Acetylation of PPARγ in macrophages promotes visceral fat degeneration in obesity.

Life metabolism

Aaron N,Zahr T,He Y,Yu L,Mayfield B,Pajvani UB,Qiang L

Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot

Thu Dec 01 00:00:00 UTC 2022

Selective targeting of visceral adiposity by polycation nanomedicine.

Nature nanotechnology

Wan Q,Huang B,Li T,Xiao Y,He Y,Du W,Wang BZ,Dakin GF,Rosenbaum M,Goncalves MD,Chen S,Leong KW,Qiang L

PA1-054 was used in Western Blotting to highlight a strategy to target visceral adiposity and suggests that cationic nanomaterials could be exploited for treating metabolic diseases.

Thu Dec 01 00:00:00 UTC 2022

Characterization of lipoprotein lipase storage vesicles in 3T3-L1 adipocytes.

Journal of cell science

Roberts BS,Yang CQ,Neher SB

PA1-054 was used in Western Blot to show that the LPL trafficking pathway shares some characteristics of these other pathways, but that LPL subcellular localization and trafficking are distinct from those of GLUT4 and leptin.

Tue Mar 01 00:00:00 UTC 2022

Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells.

Cell metabolism

Li J,Li E,Czepielewski RS,Chi J,Guo X,Han YH,Wang D,Wang L,Hu B,Dawes B,Jacobs C,Tenen D,Lin SJ,Lee B,Morris D,Tobias A,Randolph GJ,Cohen P,Tsai L,Rosen ED

PA1-054 was used in Western Blotting to establish a link between adipose tissue lymphatics and adipocytes.

Tue Jul 06 00:00:00 UTC 2021

KAT8, lysine acetyltransferase 8, is required for adipocyte differentiation in vitro.

Biochimica et biophysica acta. Molecular basis of disease

Burrell JA,Stephens JM

PA1-054 was used in Western Blotting to demonstrate that KAT8 is required for adipocyte differentiation.

Tue Jun 01 00:00:00 UTC 2021

Generation of two multipotent mesenchymal progenitor cell lines capable of osteogenic, mature osteocyte, adipogenic, and chondrogenic differentiation.

Scientific reports

Prideaux M,Wright CS,Noonan ML,Yi X,Clinkenbeard EL,Mevel E,Wheeler JA,Byers S,Wijenayaka AR,Gronthos S,Sankar U,White KE,Atkins GJ,Thompson WR

PA1-054 was used in Western Blot to develop two mesenchymal progenitor cell (MPC) lines, MPC1 and MPC2, generated from bone marrow of male C57BL/6 mice.

Fri Nov 19 00:00:00 UTC 2021

Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells.

eLife

Aaron N,Kraakman MJ,Zhou Q,Liu Q,Costa S,Yang J,Liu L,Yu L,Wang L,He Y,Fan L,Hirakawa H,Ding L,Lo J,Wang W,Zhao B,Guo E,Sun L,Rosen CJ,Qiang L

PA1-054 was used in Western Blot to reveal a novel mechanism whereby the BM sustains its own plasticity through paracrine and endocrine actions of a unique adipokine.

Tue Jun 22 00:00:00 UTC 2021

Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells.

eLife

Aaron N,Kraakman MJ,Zhou Q,Liu Q,Costa S,Yang J,Liu L,Yu L,Wang L,He Y,Fan L,Hirakawa H,Ding L,Lo J,Wang W,Zhao B,Guo E,Sun L,Rosen CJ,Qiang L

PA1-054 was used in Western Blot to reveal a novel mechanism whereby the BM sustains its own plasticity through paracrine and endocrine actions of a unique adipokine.

Tue Jun 22 00:00:00 UTC 2021

Bacillus subtilis Spore-Trained Dendritic Cells Enhance the Generation of Memory T Cells via ICAM1.

Cells

Lin J,Huang L,Li Y,Zhang P,Yu Q,Yang Q

Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot

Tue Aug 31 00:00:00 UTC 2021

The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage.

Proceedings of the National Academy of Sciences of the United States of America

Gunn KH,Roberts BS,Wang F,Strauss JD,Borgnia MJ,Egelman EH,Neher SB

PA1-054 was used in Immunocytochemistry-immunoflourescence to present a cryo-EM reconstruction of a helical LPL oligomer at 3.8-Å resolution.

Tue May 12 00:00:00 UTC 2020

The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage.

Proceedings of the National Academy of Sciences of the United States of America

Gunn KH,Roberts BS,Wang F,Strauss JD,Borgnia MJ,Egelman EH,Neher SB

PA1-054 was used in Immunocytochemistry-immunoflourescence to present a cryo-EM reconstruction of a helical LPL oligomer at 3.8-Å resolution.

Tue May 12 00:00:00 UTC 2020

Mitochondrial Pyruvate Carriers are not Required for Adipogenesis but are Regulated by High-Fat Feeding in Brown Adipose Tissue.

Obesity (Silver Spring, Md.)

Burrell JA,Richard AJ,King WT,Stephens JM

PA1-054 was used in Western Blot to assess the role of mitochondrial pyruvate carriers (MPCs) in adipocyte development in vitro and determine whether MPCs are regulated in vivo by high-fat feeding in male and female C57BL/6J mice.

Sat Feb 01 00:00:00 UTC 2020

β-Catenin Preserves the Stem State of Murine Bone Marrow Stromal Cells Through Activation of EZH2.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Sen B,Paradise CR,Xie Z,Sankaran J,Uzer G,Styner M,Meyer M,Dudakovic A,van Wijnen AJ,Rubin J

PA1-054 was used in Western Blotting to indicate that regulating EZH2 activity is key to β-catenin's effects on BMSCs to preserve multipotentiality.

Mon Jun 01 00:00:00 UTC 2020

Sirt3 regulates adipogenesis and adipokine secretion via its enzymatic activity.

Pharmacology research & perspectives

Ma O,Le T,Talbott G,HoangThao Nguyen T,Ha D,Ho L

PA1-054 was used in Western Blot to discover that Sirt3 plays a role in modulating adipogenesis and adiponectin/adipdokine expression.

Tue Dec 01 00:00:00 UTC 2020

Sirt3 regulates adipogenesis and adipokine secretion via its enzymatic activity.

Pharmacology research & perspectives

Ma O,Le T,Talbott G,HoangThao Nguyen T,Ha D,Ho L

PA1-054 was used in Western Blot to discover that Sirt3 plays a role in modulating adipogenesis and adiponectin/adipdokine expression.

Tue Dec 01 00:00:00 UTC 2020

Adiponectin accounts for gender differences in hepatocellular carcinoma incidence.

The Journal of experimental medicine

Manieri E,Herrera-Melle L,Mora A,Tomás-Loba A,Leiva-Vega L,Fernández DI,Rodríguez E,Morán L,Hernández-Cosido L,Torres JL,Seoane LM,Cubero FJ,Marcos M,Sabio G

Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot

Mon May 06 00:00:00 UTC 2019

PPARγ deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects.

The Journal of clinical investigation

Kraakman MJ,Liu Q,Postigo-Fernandez J,Ji R,Kon N,Larrea D,Namwanje M,Fan L,Chan M,Area-Gomez E,Fu W,Creusot RJ,Qiang L

PA1-054 was used in Western Blotting to show that targeted PPARγ mutations result in constitutive deacetylation, increased energy expenditure and protect from visceral adiposity and diet-induced obesity by augmenting brown remodelling of white adipose tissues.

Fri Jun 01 00:00:00 UTC 2018

LARG GEF and ARHGAP18 orchestrate RhoA activity to control mesenchymal stem cell lineage.

Bone

Thompson WR,Yen SS,Uzer G,Xie Z,Sen B,Styner M,Burridge K,Rubin J

PA1-054 was used in Western Blotting to show on and off GTP exchangers work through RhoA to influence MSC fate and responses to static and dynamic physical factors in the microenvironment.

Thu Feb 01 00:00:00 UTC 2018

Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release.

JCI insight

Obata Y,Kita S,Koyama Y,Fukuda S,Takeda H,Takahashi M,Fujishima Y,Nagao H,Masuda S,Tanaka Y,Nakamura Y,Nishizawa H,Funahashi T,Ranscht B,Izumi Y,Bamba T,Fukusaki E,Hanayama R,Shimada S,Maeda N,Shimomura I

PA1-054 was used in Western Blotting to demonstrate that the adiponectin/T-cadherin system enhances exosome biogenesis and secretion, leading to the decrease of cellular ceramides.

Thu Apr 19 00:00:00 UTC 2018

Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release.

JCI insight

PA1-054 was used in Western Blotting to demonstrate that the adiponectin/T-cadherin system enhances exosome biogenesis and secretion, leading to the decrease of cellular ceramides.

Thu Apr 19 00:00:00 UTC 2018

Distinct adipocyte progenitor cells are associated with regional phenotypes of perivascular aortic fat in mice.

Molecular metabolism

Tran KV,Fitzgibbons T,Min SY,DeSouza T,Corvera S

Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot

Thu Mar 01 00:00:00 UTC 2018

Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue.

PloS one

Jager M,Lee MJ,Li C,Farmer SR,Fried SK,Layne MD

PA1-054 was used in Western Blotting to investigate the role of aortic carboxypeptidase-like protein on adipose progenitor differentiation in the context of adipose tissue fibrosis.

Tue Dec 11 00:00:00 UTC 2018

Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles.

Journal of extracellular vesicles

Durcin M,Fleury A,Taillebois E,Hilairet G,Krupova Z,Henry C,Truchet S,Trötzmüller M,Köfeler H,Mabilleau G,Hue O,Andriantsitohaina R,Martin P,Le Lay S

PA1054 was used in western blot to describe extracellular vesicle subpopulations secreted by fat cells

Thu Oct 01 00:00:00 UTC 2020

Adipocytes play an etiological role in the podocytopathy of high-fat diet-fed rats.

The Journal of endocrinology

Chen JY,Jian DY,Lien CC,Lin YT,Ting CH,Chen LK,Hsu TC,Huang HM,Wu YT,Kuan TT,Chao YW,Wu LY,Huang SW,Juan CC

PA1054 was used in blocking or activating experiment to elucidate the relationship between obesity and chronic kidney disease

Tue Nov 01 00:00:00 UTC 2016

Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue.

Scientific reports

Ronkainen J,Huusko TJ,Soininen R,Mondini E,Cinti F,Mäkelä KA,Kovalainen M,Herzig KH,Järvelin MR,Sebert S,Savolainen MJ,Salonurmi T

PA1-054 was used in western blot to elucidate the relationship among FTO, IRX3 and fat metabolism.

Wed Mar 18 00:00:00 UTC 2015

Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells.

Stem cells (Dayton, Ohio)

Thompson WR,Guilluy C,Xie Z,Sen B,Brobst KE,Yen SS,Uzer G,Styner M,Case N,Burridge K,Rubin J

PA1-054 was used in western blot to study the regulation of adipogenesis by mechanical strain in mesenchymal stem cells and the roles played by Fyn, mTORC2 and RhoA

Fri Nov 01 00:00:00 UTC 2013

T-cadherin is essential for adiponectin-mediated revascularization.

The Journal of biological chemistry

Parker-Duffen JL,Nakamura K,Silver M,Kikuchi R,Tigges U,Yoshida S,Denzel MS,Ranscht B,Walsh K

PA1-054 was used in immunohistochemistry to study the role of T-cadherin in the mechanism by which adiponectin promotes revascularization

Fri Aug 23 00:00:00 UTC 2013

Activation of AMPK-Sirt1 pathway by telmisartan in white adipose tissue: A possible link to anti-metabolic effects.

European journal of pharmacology

Shiota A,Shimabukuro M,Fukuda D,Soeki T,Sato H,Uematsu E,Hirata Y,Kurobe H,Sakaue H,Nakaya Y,Masuzaki H,Sata M

PA1-054 was used in western blot to study the activation of the AMPK-Sirt1 pathway in white adipose tissue by telmisartan

Fri Oct 05 00:00:00 UTC 2012

St. John's Wort inhibits insulin signaling in murine and human adipocytes.

Biochimica et biophysica acta

Richard AJ,Amini ZJ,Ribnicky DM,Stephens JM

PA1-054 was used in western blot to study the inhibition of human and murine adipocyte insulin signaling by extracts of St John's Wort

Sun Apr 01 00:00:00 UTC 2012

Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice.

Cardiovascular diabetology

Shiota A,Shimabukuro M,Fukuda D,Soeki T,Sato H,Uematsu E,Hirata Y,Kurobe H,Maeda N,Sakaue H,Masuzaki H,Shimomura I,Sata M

PA1-054 was used in western blot to study the role of the AMPK/SIRT1 pathway in the mechanism by which telmisartan improves skeletal muscle insulin-sensitivity in obese mice

Thu Nov 08 00:00:00 UTC 2012

The activities of lysyl hydroxylase 3 (LH3) regulate the amount and oligomerization status of adiponectin.

PloS one

Ruotsalainen H,Risteli M,Wang C,Wang Y,Karppinen M,Bergmann U,Kvist AP,Pospiech H,Herzig KH,Myllylä R

PA1-054 was used in western blot to study the modulation of adiponectin levels and oligimerization by lysyl hydroxylase-3

Tue Jun 11 00:00:00 UTC 2013

STAT5A expression in Swiss 3T3 cells promotes adipogenesis in vivo in an athymic mice model system.

Obesity (Silver Spring, Md.)

Stewart WC,Pearcy LA,Floyd ZE,Stephens JM

PA1-054 was used in western blot to investigate the effect of STAT5A on adipogenesis

Thu Sep 01 00:00:00 UTC 2011

STAT5A expression in Swiss 3T3 cells promotes adipogenesis in vivo in an athymic mice model system.

Obesity (Silver Spring, Md.)

Stewart WC,Pearcy LA,Floyd ZE,Stephens JM

PA1-054 was used in western blot to investigate the effect of STAT5A on adipogenesis

Thu Sep 01 00:00:00 UTC 2011

N-linked glycosylation of mouse adiponectin.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

Tanaka M,Fukuhara A,Shimomura I

PA1-054 was used in western blot to characterize mouse adiponectin in terms of post-translational modification

Fri Jul 01 00:00:00 UTC 2011

T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion.

Islets

Tyrberg B,Miles P,Azizian KT,Denzel MS,Nieves ML,Monosov EZ,Levine F,Ranscht B

PA1-054 was used in Immunohistochemistry to suggest that synaptic vesicle membranes are predominantly retrieved via clathrin-independent endocytosis mediated by formin-dependent actin assembly.

Fri Jun 01 00:00:00 UTC 2012

Comparative epigenomic analysis of murine and human adipogenesis.

Cell

Mikkelsen TS,Xu Z,Zhang X,Wang L,Gimble JM,Lander ES,Rosen ED

Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot

Fri Oct 01 00:00:00 UTC 2010

Characteristic increase in nucleocytoplasmic protein glycosylation by O-GlcNAc in 3T3-L1 adipocyte differentiation.

Biochemical and biophysical research communications

Ishihara K,Takahashi I,Tsuchiya Y,Hasegawa M,Kamemura K

PA1-054 was used in western blot to investigate the effect of glycosylation on adipogenesis

Fri Jul 30 00:00:00 UTC 2010

Adiponectin deficiency limits tumor vascularization in the MMTV-PyV-mT mouse model of mammary cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Denzel MS,Hebbard LW,Shostak G,Shapiro L,Cardiff RD,Ranscht B

PA1-054 was used in immunocytochemistry to investigate the effect of adiponectin on tumor angiogenesis in in a mammary cancer mouse model.

Fri May 15 00:00:00 UTC 2009

T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model.

Cancer research

Hebbard LW,Garlatti M,Young LJ,Cardiff RD,Oshima RG,Ranscht B

PA1-054 was used in immunohistochemistry to study the role of T-cadherin in angiogenesis.

Sat Mar 01 00:00:00 UTC 2008

TRB3 blocks adipocyte differentiation through the inhibition of C/EBPbeta transcriptional activity.

Molecular and cellular biology

Bezy O,Vernochet C,Gesta S,Farmer SR,Kahn CR

PA1-054 was used in western blot to study the role of Tribbles homologue 3 TRB3 during adipogenesis.

Mon Oct 01 00:00:00 UTC 2007

The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits cell proliferation and increases markers of adipocyte maturation in cultured mouse 3T3 F442A preadipocytes.

Molecular pharmacology

Gary-Bobo M,Elachouri G,Scatton B,Le Fur G,Oury-Donat F,Bensaid M

PA1-054 was used in western blot to study the effect of rimonabant on endocrine function of mouse 3T3 F442A preadipocytes

Wed Feb 01 00:00:00 UTC 2006

JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes.

The Journal of biological chemistry

Nguyen MT,Satoh H,Favelyukis S,Babendure JL,Imamura T,Sbodio JI,Zalevsky J,Dahiyat BI,Chi NW,Olefsky JM

PA1-054 was used in western blot to investigate the role of JNK and tumor necrosis factor-alpha in free fatty acid-induced insulin resistance in 3T3-L1 adipocytes.

Fri Oct 21 00:00:00 UTC 2005

Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes.

The Journal of biological chemistry

Guilherme A,Soriano NA,Furcinitti PS,Czech MP

PA1-054 was used in western blot to investigate the function of EHD1 and EHBP1 in perinuclear localization of GLUT4.

Fri Sep 17 00:00:00 UTC 2004

Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats.

Proceedings of the National Academy of Sciences of the United States of America

Shklyaev S,Aslanidi G,Tennant M,Prima V,Kohlbrenner E,Kroutov V,Campbell-Thompson M,Crawford J,Shek EW,Scarpace PJ,Zolotukhin S

Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot

Tue Nov 25 00:00:00 UTC 2003

Bioinformatics

Protein Aliases: 30 kDa adipocyte complement-related protein; ACRP30; adipocyte complement related protein; Adipocyte complement-related 30 kDa protein; adipocyte, C1Q and collagen domain containing; Adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ; Adiponectin; ADPIOQ

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Gene Aliases: 30kDa; Acdc; Acrp30; Ad; adipo; Adipoq; Apm1; APN; GBP28

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UniProt ID: (Mouse) Q60994

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Entrez Gene ID: (Mouse) 11450

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Function(s)

receptor binding hormone activity protein binding sialic acid binding identical protein binding protein homodimerization activity

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Adiponectin Polyclonal Antibody

Adiponectin Antibody (PA1-054) in ICC/IF

Product Details

PA1-054

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Blocking Assay (BLOCK)

Mass Spectrometry (MS)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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