Product References
Micromolding-based encapsulation of mesenchymal stromal cells in alginate for intraarticular injection in osteoarthritis.
Materials today. Bio
Nativel F,Smith A,Boulestreau J,Lépine C,Baron J,Marquis M,Vignes C,Le Guennec Y,Veziers J,Lesoeur J,Loll F,Halgand B,Renard D,Abadie J,Legoff B,Blanchard F,Gauthier O,Vinatier C,Rieux AD,Guicheux J,Le Visage C
MA3-16888 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to establish the feasibility, safety, and efficacy of injecting cells encapsulated in microgels, opening the door to a long-term follow-up in canine OA patients.
Sat Apr 01 00:00:00 UTC 2023
Micromolding-based encapsulation of mesenchymal stromal cells in alginate for intraarticular injection in osteoarthritis.
Materials today. Bio
Nativel F,Smith A,Boulestreau J,Lépine C,Baron J,Marquis M,Vignes C,Le Guennec Y,Veziers J,Lesoeur J,Loll F,Halgand B,Renard D,Abadie J,Legoff B,Blanchard F,Gauthier O,Vinatier C,Rieux AD,Guicheux J,Le Visage C
MA3-16888 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to establish the feasibility, safety, and efficacy of injecting cells encapsulated in microgels, opening the door to a long-term follow-up in canine OA patients.
Sat Apr 01 00:00:00 UTC 2023
Alterations of bovine nucleus pulposus cells with aging.
Aging cell
Molinos M,Fiordalisi MF,Caldeira J,Almeida CR,Barbosa MA,Gonçalves RM
Published figure using Aggrecan monoclonal antibody (Product # MA3-16888) in Immunohistochemistry (Paraffin)
Tue Aug 01 00:00:00 UTC 2023
Irisin Role in Chondrocyte 3D Culture Differentiation and Its Possible Applications.
Pharmaceutics
Posa F,Zerlotin R,Ariano A,Cosola MD,Colaianni G,Fazio AD,Colucci S,Grano M,Mori G
MA3-16888 was used in Immunocytochemistry-immunofluorescence to reveal new crosstalk mechanisms between muscle and cartilage tissue.
Thu Feb 09 00:00:00 UTC 2023
circPhc3 sponging microRNA‑93‑3p is involved in the regulation of chondrocyte function by mechanical instability in osteoarthritis.
International journal of molecular medicine
Wang Z,Rao Z,Wang X,Jiang C,Yang Y
MA3-16888 was used in Immunocytochemistry and Western Blot to indicate that circPhc3 may serve an important role in the progression of OA and may be a good target for the treatment of OA.
Sat Jan 01 00:00:00 UTC 2022
circPhc3 sponging microRNA‑93‑3p is involved in the regulation of chondrocyte function by mechanical instability in osteoarthritis.
International journal of molecular medicine
Wang Z,Rao Z,Wang X,Jiang C,Yang Y
MA3-16888 was used in Immunocytochemistry and Western Blot to indicate that circPhc3 may serve an important role in the progression of OA and may be a good target for the treatment of OA.
Sat Jan 01 00:00:00 UTC 2022
circPhc3 sponging microRNA‑93‑3p is involved in the regulation of chondrocyte function by mechanical instability in osteoarthritis.
International journal of molecular medicine
Wang Z,Rao Z,Wang X,Jiang C,Yang Y
MA3-16888 was used in Immunocytochemistry and Western Blot to indicate that circPhc3 may serve an important role in the progression of OA and may be a good target for the treatment of OA.
Sat Jan 01 00:00:00 UTC 2022
Modulation of miR-204 Expression during Chondrogenesis.
International journal of molecular sciences
Dalle Carbonare L,Bertacco J,Minoia A,Cominacini M,Bhandary L,Elia R,Gambaro G,Mottes M,Valenti MT
Published figure using Aggrecan monoclonal antibody (Product # MA3-16888) in Western Blot
Tue Feb 15 00:00:00 UTC 2022
miRNA induced 3D bioprinted-heterotypic osteochondral interface.
Biofabrication
Celik N,Kim MH,Yeo M,Kamal F,Hayes DJ,Ozbolat IT
MA3-16888 was used in Immunohistochemistry to demonstrate that miR-transfected ADSC spheroids exhibited upregulated expression of osteogenic and chondrogenic differentiation related gene and protein markers, and enhanced mineralization and cell proliferation compared to spheroids differentiated using a commercially-available differentiation medium.
Wed Aug 17 00:00:00 UTC 2022
Circadian rhythm modulates endochondral bone formation via MTR1/AMPKβ1/BMAL1 signaling axis.
Cell death and differentiation
Yu S,Tang Q,Chen G,Lu X,Yin Y,Xie M,Long Y,Zheng W,Guo F,Shao L,Shi A,Chen L
MA3-16888 was used in Immunohistochemistry-immunofluorescence to suggest that the AMPKβ1 signaling activators are promising medications toward endochondral ossification deformities.
Fri Apr 01 00:00:00 UTC 2022
SIRT3 mitigates intervertebral disc degeneration by delaying oxidative stress-induced senescence of nucleus pulposus cells.
Journal of cellular physiology
Lin J,Du J,Wu X,Xu C,Liu J,Jiang L,Cheng X,Ge G,Chen L,Pang Q,Geng D,Mao H
Published figure using Aggrecan monoclonal antibody (Product # MA3-16888) in Western Blot
Wed Sep 01 00:00:00 UTC 2021
In vitro temporal HIF-mediated deposition of osteochondrogenic matrix governed by hypoxia and osteogenic factors synergy.
Journal of cellular physiology
Calejo I,Costa-Almeida R,Reis RL,Gomes ME
MA3-16888 was used in Immunocytochemistry-immunofluorescence to reveal a link between biochemical factors and cell-cell crosstalk, providing a molecular framework for hypoxic control and modulation of cells' fate toward enthesis-like phenotypes.
Sat May 01 00:00:00 UTC 2021
In vitro temporal HIF-mediated deposition of osteochondrogenic matrix governed by hypoxia and osteogenic factors synergy.
Journal of cellular physiology
Calejo I,Costa-Almeida R,Reis RL,Gomes ME
MA3-16888 was used in Immunocytochemistry-immunofluorescence to reveal a link between biochemical factors and cell-cell crosstalk, providing a molecular framework for hypoxic control and modulation of cells' fate toward enthesis-like phenotypes.
Sat May 01 00:00:00 UTC 2021
Ultrasound-targeted simvastatin-loaded microbubble destruction promotes OA cartilage repair by modulating the cholesterol efflux pathway mediated by PPARγ in rabbits.
Bone & joint research
Wang X,Wang D,Xia P,Cheng K,Wang Q,Wang X,Lin Q,Song J,Chen A,Li X
Published figure using Aggrecan monoclonal antibody (Product # MA3-16888) in Immunohistochemistry
Fri Oct 01 00:00:00 UTC 2021
Ultrasound-targeted simvastatin-loaded microbubble destruction promotes OA cartilage repair by modulating the cholesterol efflux pathway mediated by PPARγ in rabbits.
Bone & joint research
Wang X,Wang D,Xia P,Cheng K,Wang Q,Wang X,Lin Q,Song J,Chen A,Li X
Published figure using Aggrecan monoclonal antibody (Product # MA3-16888) in Immunohistochemistry
Fri Oct 01 00:00:00 UTC 2021
Ultrasound-targeted simvastatin-loaded microbubble destruction promotes OA cartilage repair by modulating the cholesterol efflux pathway mediated by PPARγ in rabbits.
Bone & joint research
Wang X,Wang D,Xia P,Cheng K,Wang Q,Wang X,Lin Q,Song J,Chen A,Li X
Published figure using Aggrecan monoclonal antibody (Product # MA3-16888) in Immunohistochemistry
Fri Oct 01 00:00:00 UTC 2021
Precision 3D printed meniscus scaffolds to facilitate hMSCs proliferation and chondrogenic differentiation for tissue regeneration.
Journal of nanobiotechnology
Deng X,Chen X,Geng F,Tang X,Li Z,Zhang J,Wang Y,Wang F,Zheng N,Wang P,Yu X,Hou S,Zhang W
Published figure using Aggrecan monoclonal antibody (Product # MA3-16888) in Immunocytochemistry
Thu Dec 02 00:00:00 UTC 2021
Precision 3D printed meniscus scaffolds to facilitate hMSCs proliferation and chondrogenic differentiation for tissue regeneration.
Journal of nanobiotechnology
Deng X,Chen X,Geng F,Tang X,Li Z,Zhang J,Wang Y,Wang F,Zheng N,Wang P,Yu X,Hou S,Zhang W
Published figure using Aggrecan monoclonal antibody (Product # MA3-16888) in Immunocytochemistry
Thu Dec 02 00:00:00 UTC 2021
Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide.
Scientific reports
Santamaria S,Cuffaro D,Nuti E,Ciccone L,Tuccinardi T,Liva F,D'Andrea F,de Groot R,Rossello A,Ahnström J
MA3-16888 was used in Western Blot to design a new class of sugar-based arylsulfonamides.
Wed Jan 13 00:00:00 UTC 2021
Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide.
Scientific reports
Santamaria S,Cuffaro D,Nuti E,Ciccone L,Tuccinardi T,Liva F,D'Andrea F,de Groot R,Rossello A,Ahnström J
MA3-16888 was used in Western Blot to design a new class of sugar-based arylsulfonamides.
Wed Jan 13 00:00:00 UTC 2021
Post-translational regulation and proteolytic activity of the metalloproteinase ADAMTS8.
The Journal of biological chemistry
Santamaria S,Martin DR,Dong X,Yamamoto K,Apte SS,Ahnström J
Published figure using Aggrecan monoclonal antibody (Product # MA3-16888) in Western Blot
Mon Nov 01 00:00:00 UTC 2021
Xanthohumol Attenuated Inflammation and ECM Degradation by Mediating HO-1/C/EBPβ Pathway in Osteoarthritis Chondrocytes.
Frontiers in pharmacology
Zhang M,Zhang R,Zheng T,Chen Z,Ji G,Peng F,Wang W
Published figure using Aggrecan monoclonal antibody (Product # MA3-16888) in Western Blot
Sun May 23 00:00:00 UTC 2021
Hyaluronic acid hydrogels reinforced with laser spun bioactive glass micro- and nanofibres doped with lithium.
Materials science & engineering. C, Materials for biological applications
Riveiro A,Amorim S,Solanki A,Costa DS,Pires RA,Quintero F,Del Val J,Comesaña R,Badaoui A,Lusquiños F,Maçon ALB,Tallia F,Jones JR,Reis RL,Pou J
MA3-16888 was used in Western Blotting to show that hydrogel composite shows potential application in regeneration of subchondral defects.
Thu Jul 01 00:00:00 UTC 2021
Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis.
Cell research
Wu J,Song D,Li Z,Guo B,Xiao Y,Liu W,Liang L,Feng C,Gao T,Chen Y,Li Y,Wang Z,Wen J,Yang S,Liu P,Wang L,Wang Y,Peng L,Stacey GN,Hu Z,Feng G,Li W,Huo Y,Jin R,Shyh-Chang N,Zhou Q,Wang L,Hu B,Dai H,Hao J
MA3-16888 was used in Immunocytochemistry-immunoflourescence to investigate the use of hESC-derived immunity-regulatory and matrix-regulatory cells in treating lung injury and fibrosis in mice.
Tue Sep 01 00:00:00 UTC 2020
Basement Membrane Remodeling Controls Endothelial Function in Idiopathic Pulmonary Arterial Hypertension.
American journal of respiratory cell and molecular biology
Jandl K,Marsh LM,Hoffmann J,Mutgan AC,Baum O,Bloch W,Thekkekara-Puthenparampil H,Kolb D,Sinn K,Klepetko W,Heinemann A,Olschewski A,Olschewski H,Kwapiszewska G
MA3-16888 was used in Immunohistochemistry to show the importance of a well-maintained BM homeostasis and suggest an active involvement of the BM in IPAH pathogenesis.
Wed Jul 01 00:00:00 UTC 2020
Increased matrix metalloproteinase levels and perineuronal net proteolysis in the HIV-infected brain; relevance to altered neuronal population dynamics.
Experimental neurology
Bozzelli PL,Caccavano A,Avdoshina V,Mocchetti I,Wu JY,Conant K
MA3-16888 was used in Western Blotting to show that levels of PNN-degrading matrix metalloproteinases (MMPs) are elevated in HIV-infected post-mortem human brain tissue.
Wed Jan 01 00:00:00 UTC 2020
Silencing of long‑chain non‑coding RNA GAS5 in osteoarthritic chondrocytes is mediated by targeting the miR‑34a/Bcl‑2 axis.
Molecular medicine reports
Ji Q,Qiao X,Liu Y,Wang D,Yan J
MA3-16888 was used in Western Blot to indicate that GAS5 participated in the development of OA by regulating the biological behavior of chondrocytes via the miR‚34a/Bcl‚2 axis.
Sun Mar 01 00:00:00 UTC 2020
TLR2 Promotes Vascular Smooth Muscle Cell Chondrogenic Differentiation and Consequent Calcification via the Concerted Actions of Osteoprotegerin Suppression and IL-6-Mediated RANKL Induction.
Arteriosclerosis, thrombosis, and vascular biology
Lee GL,Yeh CC,Wu JY,Lin HC,Wang YF,Kuo YY,Hsieh YT,Hsu YJ,Kuo CC
MA3-16888 was used in Immunohistochemistry to study the role of Toll-like receptor 2 in vascular calcification during atherosclerosis.
Fri Mar 01 00:00:00 UTC 2019
Non-pathological Chondrogenic Features of Valve Interstitial Cells in Normal Adult Zebrafish.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Schulz A,Brendler J,Blaschuk O,Landgraf K,Krueger M,Ricken AM
MA3-16888 was used in Immunohistochemistry to investigate the microarchitecture and differentiation of cardiac valve interstitial cells in the transition from juvenile (35 days) to end of adult breeding (2.5 years) stages in zebrafish (ZF, Danio rerio).
Wed May 01 00:00:00 UTC 2019
Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity.
Scientific reports
Buken C,Sahana J,Corydon TJ,Melnik D,Bauer J,Wehland M,Krüger M,Balk S,Abuagela N,Infanger M,Grimm D
MA3-16888 was used in Flow cytometry/Cell sorting to show simulated microgravity causes changes in the cytoskeleton, extracellular matrix, focal adhesion and growth behaviour of normal human dermal fibroblasts and to identify the factors involved in the assembly of the fibroblasts.
Thu Aug 15 00:00:00 UTC 2019
Notch Signaling Regulates MMP-13 Expression via Runx2 in Chondrocytes.
Scientific reports
Xiao D,Bi R,Liu X,Mei J,Jiang N,Zhu S
MA3-16888 was used in Western Blotting to study Notch signalling as a regulator for rat chondrocyte proliferation and diferentiation.
Wed Oct 30 00:00:00 UTC 2019
Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis.
Scientific reports
Santamaria S,Yamamoto K,Teraz-Orosz A,Koch C,Apte SS,de Groot R,Lane DA,Ahnström J
MA3-16888 was used in Western Blotting to study the role of spacer domain hypervariable loops in the regulation of ADAMTS proteolytic activity.
Mon Jul 29 00:00:00 UTC 2019
Intraarticular senescent chondrocytes impair the cartilage regeneration capacity of mesenchymal stem cells.
Stem cell research & therapy
Cao X,Luo P,Huang J,Liang C,He J,Wang Z,Shan D,Peng C,Wu S
MA3-16888 was used in Western Blotting to study the influence of senescent chondrocytes on exogenously transplanted stem cells.
Tue Mar 12 00:00:00 UTC 2019
Andrographolide mitigates IL‑1β‑induced human nucleus pulposus cells degeneration through the TLR4/MyD88/NF‑κB signaling pathway.
Molecular medicine reports
Zhang L,Chen Q,Wang H,Yang J,Sheng S
MA3-16888 was used in Immunocytochemistry-immunoflourescence to investigate the effects and mechanisms of andrographolide on intervertebral disc degeneration in human nucleus pulposus cells.
Sat Dec 01 00:00:00 UTC 2018
Andrographolide mitigates IL‑1β‑induced human nucleus pulposus cells degeneration through the TLR4/MyD88/NF‑κB signaling pathway.
Molecular medicine reports
Zhang L,Chen Q,Wang H,Yang J,Sheng S
MA3-16888 was used in Immunocytochemistry-immunoflourescence to investigate the effects and mechanisms of andrographolide on intervertebral disc degeneration in human nucleus pulposus cells.
Sat Dec 01 00:00:00 UTC 2018
A fully defined static suspension culture system for large-scale human embryonic stem cell production.
Cell death & disease
Li X,Ma R,Gu Q,Liang L,Wang L,Zhang Y,Wang X,Liu X,Li Z,Fang J,Wu J,Wang Y,Li W,Hu B,Wang L,Zhou Q,Hao J
MA3-16888 was used in Immunocytochemistry to characterise a static suspension culture system for large-scale human embryonic stem cell production.
Thu Aug 30 00:00:00 UTC 2018
Three-Dimensional Coculture of Meniscal Cells and Mesenchymal Stem Cells in Collagen Type I Hydrogel on a Small Intestinal Matrix-A Pilot Study Toward Equine Meniscus Tissue Engineering.
Tissue engineering. Part A
Kremer A,Ribitsch I,Reboredo J,Dürr J,Egerbacher M,Jenner F,Walles H
MA316888 was used in immunohistochemistry to compare 3D co-culture constructs of primary equine mesenchymal stem cells and meniscus cells for their qualification to be applied for meniscus tissue engineering
Mon May 01 00:00:00 UTC 2017
Approaching the compressive modulus of articular cartilage with a decellularized cartilage-based hydrogel.
Acta biomaterialia
Beck EC,Barragan M,Tadros MH,Gehrke SH,Detamore MS
MA3-16888 was used in immunohistochemistry - paraffin section to utilize a decellularized cartilage-based hydrogel to help with the compressive modulus of articular cartilage
Fri Jul 01 00:00:00 UTC 2016
Chondroinductive Hydrogel Pastes Composed of Naturally Derived Devitalized Cartilage.
Annals of biomedical engineering
Beck EC,Barragan M,Tadros MH,Kiyotake EA,Acosta FM,Kieweg SL,Detamore MS
MA3-16888 was used in immunohistochemistry - frozen section to research naturally derived devitalized cartilage used as chondroinductive hydrogel pastes
Wed Jun 01 00:00:00 UTC 2016
Chondroinduction from Naturally Derived Cartilage Matrix: A Comparison Between Devitalized and Decellularized Cartilage Encapsulated in Hydrogel Pastes.
Tissue engineering. Part A
Beck EC,Barragan M,Libeer TB,Kieweg SL,Converse GL,Hopkins RA,Berkland CJ,Detamore MS
MA3-16888 was used in immunohistochemistry - frozen section to compare devitalized and decellularized cartilage encapsulated in hydrogel pastes as chondroinduction from naturally derived cartilage matrix
Fri Apr 01 00:00:00 UTC 2016
Cx43-Dependent Skeletal Phenotypes Are Mediated by Interactions between the Hapln1a-ECM and Sema3d during Fin Regeneration.
PloS one
Govindan J,Tun KM,Iovine MK
MA3-16888 was used in immunohistochemistry - paraffin section to analyze how Cx43-dependent skeletal phenotypes are mediated by interactions between Sema3d and HapIn1a-ECM during regeneration of fins
Tue Jul 19 00:00:00 UTC 2016
Olive and grape seed extract prevents post-traumatic osteoarthritis damages and exhibits in vitro anti IL-1β activities before and after oral consumption.
Scientific reports
Mével E,Merceron C,Vinatier C,Krisa S,Richard T,Masson M,Lesoeur J,Hivernaud V,Gauthier O,Abadie J,Nourissat G,Houard X,Wittrant Y,Urban N,Beck L,Guicheux J
MA3-16888 was used in Immunohistochemistry to conclude that HT/PCy extract may be of clinical significance for the preventive treatment of osteoarthritis.
Mon Sep 19 00:00:00 UTC 2016
Dynamic remodeling of the extra cellular matrix during zebrafish fin regeneration.
Gene expression patterns : GEP
Govindan J,Iovine MK
MA3-16888 was used in immunohistochemistry - frozen section to analyze extracellular matrix protein expression during caudal fin regeneration in zebrafish.
Thu Sep 08 00:00:00 UTC 2016
Proteomic profiling and functional characterization of early and late shoulder osteoarthritis.
Arthritis research & therapy
Wanner J,Subbaiah R,Skomorovska-Prokvolit Y,Shishani Y,Boilard E,Mohan S,Gillespie R,Miyagi M,Gobezie R
MA3-16888 was used in western blot to establish comparative proteomic profiles of healthy shoulders and those in the early and late stages of osteoarthritis
Wed Nov 06 00:00:00 UTC 2013
Lyme disease spirochaetes possess an aggrecan-binding protease with aggrecanase activity.
Molecular microbiology
Russell TM,Johnson BJ
MA3-16888 was used in western blot to study a novel aggrecanase produced by the Lyme disease spirochaete during human infection and the pathogenic significance
Tue Oct 01 00:00:00 UTC 2013
Effects of a glycogen synthase kinase-3β inhibitor (LiCl) on c-myc protein in intervertebral disc cells.
Journal of cellular biochemistry
Hiyama A,Sakai D,Arai F,Nakajima D,Yokoyama K,Mochida J
MA3-16888 was used in immunocytochemistry to investigate the regulation of c-myc Wnt signaling
Sat Oct 01 00:00:00 UTC 2011
.jpg?time=20250104)
.jpg?time=20250104?time=20250104 "Aggrecan Antibody (MA3-16888) in IHC (F)")
