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Invitrogen
Aldolase A Recombinant Rabbit Monoclonal Antibody (21H7L6)
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FIGURE: 1 / 6
Aldolase A Antibody (702729) in ICC/IF
For immunofluorescence analysis, A549 cells were fixed and permeabilized for detection of endogenous Aldolase using Anti- Aldolase Recombinant Rabbit Monoclonal Antibody (Product # 702729, 5 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and ... View More
Product Details
702729
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
21H7L6
Immunogen
Peptides corresponding to human Aldolase A [1) aa341-aa360 2) aa84-aa103]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2722843
Product Specific Information
This antibody is predicted to react with Monkey, Cat, Rabbit
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aldolase 1; aldolase 1, A isoform; aldolase A, fructose-bisphosphate; epididymis secretory sperm binding protein Li 87p; fructose-1,6-bisphosphate triosephosphate-lyase; Fructose-bisphosphate aldolase A; Lung cancer antigen NY-LU-1; Muscle-type aldolase
Gene Aliases: ALDA; Aldo-1; Aldo1; ALDOA; GSD12; HEL-S-87p; RNALDOG5
UniProt ID: (Human) P04075, (Mouse) P05064, (Rat) P05065
Entrez Gene ID: (Human) 226, (Mouse) 11674, (Rat) 24189
fructose metabolic process
glycolytic process
ATP biosynthetic process
striated muscle contraction
regulation of cell shape
fructose 1,6-bisphosphate metabolic process
muscle cell cellular homeostasis
platelet degranulation
gluconeogenesis
actin filament organization
protein homotetramerization
canonical glycolysis
cell-cell adhesion
response to hypoxia
response to heat
response to lipopolysaccharide
response to nicotine
response to estrogen
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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