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Aldolase C Polyclonal Antibody

Aldolase C Antibody in Immunocytochemistry (ICC/IF)

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Aldolase C Antibody (14884-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using ALDOC antibody 14884-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

Aldolase C Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Aldolase C Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Aldolase C Antibody in Western Blot (WB)

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Product Details

14884-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2400

View 9 publications 9 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:10-1:100

Immunocytochemistry (ICC/IF)

1:10-1:100

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Aldolase C Fusion Protein Ag6659 (1-364 aa encoded by BC003613)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MPHSYPALS AEQKKELSDI ALRIVAPGKG ILAADESVGS MAKRLSQIGV ENTEENRRLY RQVLFSADDR VKKCIGGVIF FHETLYQKDD NGVPFVRTIQ DKGIVVGIKV DKGVVPLAGT DGETTTQGLD GLSERCAQYK KDGADFAKWR CVLKISERTP SALAILENAN VLARYASICQ QNGIVPIVEP EILPDGDHDL KRCQYVTEKV LAAVYKALSD HHVYLEGTLL KPNMVTPGHA CPIKYTPEEI AMATVTALRR TVPPAVPGVT FLSGGQSEEE ASFNLNAINR CPLPRPWALT FSYGRALQAS ALNAWRGQRD NAGAATEEFI KRAEVNGLAA QGKYEGSGED GGAAAQSLYI ANHAY (1-364 aa encoded by BC003613)

Target Information

This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Cell type- and region-specific translatomes in an MPTP mouse model of Parkinson's disease.

Neurobiology of disease

Huang Q,Chen C,Chen W,Cai C,Xing H,Li J,Li M,Ma S

Mon May 01 00:00:00 UTC 2023

The function of lactate dehydrogenase A in retinal neurons: implications to retinal degenerative diseases.

PNAS nexus

Rajala A,Bhat MA,Teel K,Gopinadhan Nair GK,Purcell L,Rajala RVS

Wed Mar 01 00:00:00 UTC 2023

The function of lactate dehydrogenase A in retinal neurons: implications to retinal degenerative diseases.

PNAS nexus

Rajala A,Bhat MA,Teel K,Gopinadhan Nair GK,Purcell L,Rajala RVS

Wed Mar 01 00:00:00 UTC 2023

Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro.

Stem cells international

Li JQ,Jiang HJ,Su XY,Feng L,Zhan NZ,Li SS,Chen ZJ,Chang BH,Cheng PZ,Yang L,Pei GX

Tue Jan 25 00:00:00 UTC 2022

O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine.

Nature communications

Kim K,Yoo HC,Kim BG,Kim S,Sung Y,Yoon I,Yu YC,Park SJ,Kim JH,Myung K,Hwang KY,Kim S,Han JM

Wed May 25 00:00:00 UTC 2022

GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase.

Cancer & metabolism

Liang RJ,Taylor S,Nahiyaan N,Song J,Murphy CJ,Dantas E,Cheng S,Hsu TW,Ramsamooj S,Grover R,Hwang SK,Ngo B,Cantley LC,Rhee KY,Goncalves MD

Wed Mar 24 00:00:00 UTC 2021

Type I interferon decreases macrophage energy metabolism during mycobacterial infection.

Cell reports

Olson GS,Murray TA,Jahn AN,Mai D,Diercks AH,Gold ES,Aderem A

Tue Jun 01 00:00:00 UTC 2021

A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.

Biochimica et biophysica acta. Molecular basis of disease

Zhu M,Wang Q,Tian P,Cheng L,Sun Z,Hong Q,Lv P,Ji L,Liu Y,Tang QQ,Wen B

Fri Jan 01 00:00:00 UTC 2021

Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in ccRCC, which Results in Different Clinical Outcomes.

Molecular therapy : the journal of the American Society of Gene Therapy

Hu J,Chen Z,Bao L,Zhou L,Hou Y,Liu L,Xiong M,Zhang Y,Wang B,Tao Z,Chen K

Wed Jul 08 00:00:00 UTC 2020

A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism.

Nature communications

Ho JJD,Balukoff NC,Theodoridis PR,Wang M,Krieger JR,Schatz JH,Lee S

Fri May 29 00:00:00 UTC 2020

C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis.

Brain : a journal of neurology

Allen SP,Hall B,Woof R,Francis L,Gatto N,Shaw AC,Myszczynska M,Hemingway J,Coldicott I,Willcock A,Job L,Hughes RM,Boschian C,Bayatti N,Heath PR,Bandmann O,Mortiboys H,Ferraiuolo L,Shaw PJ

Sun Dec 01 00:00:00 UTC 2019

The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway.

Stem cell reports

Sun Z,Zhu M,Lv P,Cheng L,Wang Q,Tian P,Yan Z,Wen B

Tue Sep 11 00:00:00 UTC 2018

The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway.

Stem cell reports

Sun Z,Zhu M,Lv P,Cheng L,Wang Q,Tian P,Yan Z,Wen B

Tue Sep 11 00:00:00 UTC 2018

Lack of CUL4B leads to increased abundance of GFAP-positive cells that is mediated by PTGDS in mouse brain.

Human molecular genetics

Zhao W,Jiang B,Hu H,Zhang S,Lv S,Yuan J,Qian Y,Zou Y,Li X,Jiang H,Liu F,Shao C,Gong Y

Sat Aug 15 00:00:00 UTC 2015

Lack of CUL4B leads to increased abundance of GFAP-positive cells that is mediated by PTGDS in mouse brain.

Human molecular genetics

Zhao W,Jiang B,Hu H,Zhang S,Lv S,Yuan J,Qian Y,Zou Y,Li X,Jiang H,Liu F,Shao C,Gong Y

Sat Aug 15 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: Aldolase 3; aldolase C, fructose-biphosphate; aldolase C, fructose-bisphosphate; Brain-type aldolase; EC 4.1.2.13; fructoaldolase C; fructose-1,6-biphosphate triosephosphate lyase; Fructose-bisphosphate aldolase C; Scrapie-responsive protein 2; Zebrin II

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Gene Aliases: AI847350; ALDC; ALDCAA; Aldo3; ALDOC; AU040929; F16dip7; RATALDCAA; Scrg2

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UniProt ID: (Human) P09972, (Mouse) P05063, (Rat) P09117

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Entrez Gene ID: (Human) 230, (Mouse) 11676, (Rat) 24191

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Function(s)

fructose-bisphosphate aldolase activity protein binding cytoskeletal protein binding

Process(es)

fructose metabolic process gluconeogenesis fructose 1,6-bisphosphate metabolic process epithelial cell differentiation canonical glycolysis response to hypoxia glycolytic process apoptotic process aging response to organonitrogen compound response to organic cyclic compound organ regeneration protein homotetramerization protein heterotetramerization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Aldolase C Polyclonal Antibody

Aldolase C Antibody (14884-1-AP) in ICC/IF

Product Details

14884-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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