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Product Details
MUB0112S
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
Amylin
Conjugate
Form
Liquid
Storage buffer
whole serum
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
RKSE60 reacts exclusively with Cytokeratin 10 which is present in Keratinizing stratified epithelia and in differentiated areas of highly differentiated squamous cell carcinomas.
The antibody may be stored at 4 C. For prolonged storage prepare appropriate aliquots and store at or below -20 C. Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at 4 C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product.
Target Information
Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Amylin; amylin peptide; DAP; Diabetes-associated peptide; IAPP; Insulinoma amyloid peptide; Islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); Rabbit Anti-Amylin
Gene Aliases: DAP; IAP; IAPP
UniProt ID: (Human) P10997
Entrez Gene ID: (Human) 3375
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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