Product References
HIV-1 promotes ubiquitination of the amyloidogenic C-terminal fragment of APP to support viral replication.
Nature communications
Gu F,Boisjoli M,Naghavi MH
13-0200 was used in Immunocytochemistry to show that entry of HIV-1 Gag into MVBs is blocked by the amyloidogenic C-terminal fragment of APP, C99 , but not by the non-amyloidogenic product C83.
Sat Jul 15 00:00:00 UTC 2023
Transferrin-Conjugated Melittin-Loaded L-Arginine-Coated Iron Oxide Nanoparticles for Mitigating Beta-Amyloid Pathology of the 5XFAD Mouse Brain.
International journal of molecular sciences
Choi M,Ryu J,Vu HD,Kim D,Youn YJ,Park MH,Huynh PT,Hwang GB,Youn SW,Jeong YH
13-0200 was used in Western Blot to provide a foundation for further exploration and advancement in AD therapeutics.
Fri Oct 06 00:00:00 UTC 2023
PLD3 affects axonal spheroids and network defects in Alzheimer's disease.
Nature
Yuan P,Zhang M,Tong L,Morse TM,McDougal RA,Ding H,Chan D,Cai Y,Grutzendler J
13-0200 was used in Immunohistochemistry to reveal a cell-intrinsic neuronal mechanism that modulates the size of axonal spheroids and the consequent axonal conduction defects, with important implications for neuronal network dysfunction.
Thu Dec 01 00:00:00 UTC 2022
Analysis of the intracellular traffic of IgG in the context of Down syndrome (trisomy 21).
Scientific reports
Cejas RB,Tamaño-Blanco M,Blanco JG
13-0200 was used in Western Blotting to analyse the intracellular traffic of IgG mediated by the human neonatal Fc receptor (FcRn) in fibroblast cell lines with trisomy 21.
Wed May 26 00:00:00 UTC 2021
Analysis of the intracellular traffic of IgG in the context of Down syndrome (trisomy 21).
Scientific reports
Cejas RB,Tamaño-Blanco M,Blanco JG
13-0200 was used in Western Blotting to analyse the intracellular traffic of IgG mediated by the human neonatal Fc receptor (FcRn) in fibroblast cell lines with trisomy 21.
Wed May 26 00:00:00 UTC 2021
Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones.
Cell biology and toxicology
Mbah NE,Overmeyer JH,Maltese WA
13-0200 was used in Western Blotting to explore the induction of methuosis as a potential therapeutic strategy for killing cancer cells.
Thu Jun 01 00:00:00 UTC 2017
Axonal motor protein KIF5A and associated cargo deficits in multiple sclerosis lesional and normal-appearing white matter.
Neuropathology and applied neurobiology
Hares K,Redondo J,Kemp K,Rice C,Scolding N,Wilkins A
13-0200 was used in western blot to study cargo deficits in multiple sclerosis lesional and normal-appearing white matter for the axonal motor protein KIF5A
Sat Apr 01 00:00:00 UTC 2017
Axonal motor protein KIF5A and associated cargo deficits in multiple sclerosis lesional and normal-appearing white matter.
Neuropathology and applied neurobiology
Hares K,Redondo J,Kemp K,Rice C,Scolding N,Wilkins A
13-0200 was used in western blot to study cargo deficits in multiple sclerosis lesional and normal-appearing white matter for the axonal motor protein KIF5A
Sat Apr 01 00:00:00 UTC 2017
HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration.
Nature communications
Chai Q,Jovasevic V,Malikov V,Sabo Y,Morham S,Walsh D,Naghavi MH
Published figure using beta Amyloid monoclonal antibody (Product # 13-0200) in Immunoprecipitation
Wed Nov 15 00:00:00 UTC 2017
HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration.
Nature communications
Chai Q,Jovasevic V,Malikov V,Sabo Y,Morham S,Walsh D,Naghavi MH
Published figure using beta Amyloid monoclonal antibody (Product # 13-0200) in Immunoprecipitation
Wed Nov 15 00:00:00 UTC 2017
HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration.
Nature communications
Chai Q,Jovasevic V,Malikov V,Sabo Y,Morham S,Walsh D,Naghavi MH
Published figure using beta Amyloid monoclonal antibody (Product # 13-0200) in Immunoprecipitation
Wed Nov 15 00:00:00 UTC 2017
Overexpression of Kinesin Superfamily Motor Proteins in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD
Hares K,Miners JS,Cook AJ,Rice C,Scolding N,Love S,Wilkins A
13-0200 was used in Western Blotting to conclude that upregulation of KIFs may be an adaptive response to impaired axonal transport in Alzheimer's disease (AD).
Mon Jul 23 00:00:00 UTC 2018
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
Neuron
Yuan P,Condello C,Keene CD,Wang Y,Bird TD,Paul SM,Luo W,Colonna M,Baddeley D,Grutzendler J
Published figure using beta Amyloid monoclonal antibody (Product # 13-0200) in Immunofluorescence
Wed May 18 00:00:00 UTC 2016
Attenuation of β-Amyloid Deposition and Neurotoxicity by Chemogenetic Modulation of Neural Activity.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Yuan P,Grutzendler J
13-0200 was used in immunohistochemistry to analyze chemogenetic modulation of neural activity by attenuation of beta-amyloid deposition and neurotoxicity
Wed Jan 13 00:00:00 UTC 2016
At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei.
Neuropathology and applied neurobiology
Reis R,Hennessy E,Murray C,Griffin ÉW,Cunningham C
13-0200 was used in immunohistochemistry - paraffin section to investigate the spread of neuronal pathology.
Thu Oct 01 00:00:00 UTC 2015
At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei.
Neuropathology and applied neurobiology
Reis R,Hennessy E,Murray C,Griffin ÉW,Cunningham C
13-0200 was used in immunohistochemistry - paraffin section to investigate the spread of neuronal pathology.
Thu Oct 01 00:00:00 UTC 2015
At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei.
Neuropathology and applied neurobiology
Reis R,Hennessy E,Murray C,Griffin ÉW,Cunningham C
13-0200 was used in immunohistochemistry - paraffin section to investigate the spread of neuronal pathology.
Thu Oct 01 00:00:00 UTC 2015
Sodium Chloride Increases Aβ Levels by Suppressing Aβ Clearance in Cultured Cells.
PloS one
Cheng XJ,Gao Y,Zhao YW,Cheng XD
Published figure using beta Amyloid monoclonal antibody (Product # 13-0200) in Western Blot
Wed May 04 00:00:00 UTC 2016
Human neural stem cells alleviate Alzheimer-like pathology in a mouse model.
Molecular neurodegeneration
Lee IS,Jung K,Kim IS,Lee H,Kim M,Yun S,Hwang K,Shin JE,Park KI
13-0200 was used in western blot to analyze a mouse model where human neural stem cells alleviate Alzheimer-like pathology
Fri Aug 21 00:00:00 UTC 2015
TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production.
Nature communications
Wang J,Lu R,Yang J,Li H,He Z,Jing N,Wang X,Wang Y
Thu Nov 19 00:00:00 UTC 2015
TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production.
Nature communications
Wang J,Lu R,Yang J,Li H,He Z,Jing N,Wang X,Wang Y
Thu Nov 19 00:00:00 UTC 2015
TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production.
Nature communications
Wang J,Lu R,Yang J,Li H,He Z,Jing N,Wang X,Wang Y
Thu Nov 19 00:00:00 UTC 2015
TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production.
Nature communications
Wang J,Lu R,Yang J,Li H,He Z,Jing N,Wang X,Wang Y
Thu Nov 19 00:00:00 UTC 2015
Neuroprotective maraviroc monotherapy in simian immunodeficiency virus-infected macaques: reduced replicating and latent SIV in the brain.
AIDS (London, England)
Kelly KM,Beck SE,Metcalf Pate KA,Queen SE,Dorsey JL,Adams RJ,Avery LB,Hubbard W,Tarwater PM,Mankowski JL
13-0200 was used in immunohistochemistry to explain how CCR5 antagonists may attenuate central nervous system disease by modulating inflammatory signaling and by limiting HIV replication.
Thu Nov 28 00:00:00 UTC 2013
Modulation of lipid kinase PI4KIIα activity and lipid raft association of presenilin 1 underlies γ-secretase inhibition by ginsenoside (20S)-Rg3.
The Journal of biological chemistry
Kang MS,Baek SH,Chun YS,Moore AZ,Landman N,Berman D,Yang HO,Morishima-Kawashima M,Osawa S,Funamoto S,Ihara Y,Di Paolo G,Park JH,Chung S,Kim TW
13-0200 was used in western blot to identify agents that can reduce Aβ levels in the brain.
Fri Jul 19 00:00:00 UTC 2013
Modulation of lipid kinase PI4KIIα activity and lipid raft association of presenilin 1 underlies γ-secretase inhibition by ginsenoside (20S)-Rg3.
The Journal of biological chemistry
Kang MS,Baek SH,Chun YS,Moore AZ,Landman N,Berman D,Yang HO,Morishima-Kawashima M,Osawa S,Funamoto S,Ihara Y,Di Paolo G,Park JH,Chung S,Kim TW
13-0200 was used in western blot to identify agents that can reduce Aβ levels in the brain.
Fri Jul 19 00:00:00 UTC 2013
Modulation of lipid kinase PI4KIIα activity and lipid raft association of presenilin 1 underlies γ-secretase inhibition by ginsenoside (20S)-Rg3.
The Journal of biological chemistry
Kang MS,Baek SH,Chun YS,Moore AZ,Landman N,Berman D,Yang HO,Morishima-Kawashima M,Osawa S,Funamoto S,Ihara Y,Di Paolo G,Park JH,Chung S,Kim TW
13-0200 was used in western blot to identify agents that can reduce Aβ levels in the brain.
Fri Jul 19 00:00:00 UTC 2013
Increasing Membrane Cholesterol Level Increases the Amyloidogenic Peptide by Enhancing the Expression of Phospholipase C.
Journal of neurodegenerative diseases
Chun YS,Oh HG,Park MK,Kim TW,Chung S
13-0200 was used in western blot to investigate the role of cholesterol in the pathogenesis of Alzheimer's disease.
Fri Aug 28 00:00:00 UTC 2015
Increasing Membrane Cholesterol Level Increases the Amyloidogenic Peptide by Enhancing the Expression of Phospholipase C.
Journal of neurodegenerative diseases
Chun YS,Oh HG,Park MK,Kim TW,Chung S
13-0200 was used in western blot to investigate the role of cholesterol in the pathogenesis of Alzheimer's disease.
Fri Aug 28 00:00:00 UTC 2015
Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system.
Translational neurodegeneration
Zheng L,Cedazo-Minguez A,Hallbeck M,Jerhammar F,Marcusson J,Terman A
13-0200 was used in immunocytochemistry to describe the intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system.
Wed Sep 26 00:00:00 UTC 2012
Phagocytosis of neuronal debris by microglia is associated with neuronal damage in multiple sclerosis.
Glia
Huizinga R,van der Star BJ,Kipp M,Jong R,Gerritsen W,Clarner T,Puentes F,Dijkstra CD,van der Valk P,Amor S
13-0200 was used in immunohistochemistry to investigate phagocytosis of neuronal antigens in a multiple sclerosis model.
Thu Mar 01 00:00:00 UTC 2012
Gas1 interferes with AβPP trafficking by facilitating the accumulation of immature AβPP in endoplasmic reticulum-associated raft subdomains.
Journal of Alzheimer's disease : JAD
Chapuis J,Vingtdeux V,Capiralla H,Davies P,Marambaud P
13-0200 was used in western blot to study the mechanism by which Gas1 blocks the intracellular trafficking of amyloid precursor protein
Wed Sep 12 00:00:00 UTC 2012
Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism.
PloS one
Killian RL,Flippin JD,Herrera CM,Almenar-Queralt A,Goldstein LS
13-0200 was used in western blot to elucidate the role of Kinesin-1 in Alzheimer disease pathogenesis.
Mon Jun 11 00:00:00 UTC 2012
Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism.
PloS one
Killian RL,Flippin JD,Herrera CM,Almenar-Queralt A,Goldstein LS
13-0200 was used in western blot to elucidate the role of Kinesin-1 in Alzheimer disease pathogenesis.
Mon Jun 11 00:00:00 UTC 2012
Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Aβ generation in Alzheimer's disease.
Molecular neurodegeneration
Saito Y,Inoue T,Zhu G,Kimura N,Okada M,Nishimura M,Kimura N,Murayama S,Kaneko S,Shigemoto R,Imoto K,Suzuki T
13-0200 was used in western blot to elucidate the molecular linkage between epileptic seizures and Abeta generation in Alzheimer's disease
Wed Oct 03 00:00:00 UTC 2012
Involvement of receptor tyrosine kinase Tyro3 in amyloidogenic APP processing and β-amyloid deposition in Alzheimer's disease models.
PloS one
Zheng Y,Wang Q,Xiao B,Lu Q,Wang Y,Wang X
13-0200 was used in western blot to study the role of receptor tyrosine kinase Tyro3 in APP processing and beta amyloid deposition.
Thu Nov 08 00:00:00 UTC 2012
Macroautophagy-generated increase of lysosomal amyloid β-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells.
Autophagy
Zheng L,Terman A,Hallbeck M,Dehvari N,Cowburn RF,Benedikz E,Kågedal K,Cedazo-Minguez A,Marcusson J
13-0200 was used in immunocytochemistry to study the contribution of macroautophagy to lysosomal Aβ accumulation.
Thu Dec 01 00:00:00 UTC 2011
Macroautophagy-generated increase of lysosomal amyloid β-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells.
Autophagy
Zheng L,Terman A,Hallbeck M,Dehvari N,Cowburn RF,Benedikz E,Kågedal K,Cedazo-Minguez A,Marcusson J
13-0200 was used in immunocytochemistry to study the contribution of macroautophagy to lysosomal Aβ accumulation.
Thu Dec 01 00:00:00 UTC 2011
LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ranganathan S,Noyes NC,Migliorini M,Winkles JA,Battey FD,Hyman BT,Smith E,Yepes M,Mikhailenko I,Strickland DK
13-0200 was used in immunocytochemistry to identify and characterize LDL receptor class A domain containing 3.
Wed Jul 27 00:00:00 UTC 2011
LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ranganathan S,Noyes NC,Migliorini M,Winkles JA,Battey FD,Hyman BT,Smith E,Yepes M,Mikhailenko I,Strickland DK
13-0200 was used in immunocytochemistry to identify and characterize LDL receptor class A domain containing 3.
Wed Jul 27 00:00:00 UTC 2011
LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ranganathan S,Noyes NC,Migliorini M,Winkles JA,Battey FD,Hyman BT,Smith E,Yepes M,Mikhailenko I,Strickland DK
13-0200 was used in immunocytochemistry to identify and characterize LDL receptor class A domain containing 3.
Wed Jul 27 00:00:00 UTC 2011
LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ranganathan S,Noyes NC,Migliorini M,Winkles JA,Battey FD,Hyman BT,Smith E,Yepes M,Mikhailenko I,Strickland DK
13-0200 was used in immunocytochemistry to identify and characterize LDL receptor class A domain containing 3.
Wed Jul 27 00:00:00 UTC 2011
Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor protein.
Human molecular genetics
Chapuis J,Vingtdeux V,Campagne F,Davies P,Marambaud P
13-0200 was used in immunocytochemistry and western blot to investigate the role of growth arrest-specific 1 in Alzheimer's disease
Sun May 15 00:00:00 UTC 2011
Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor protein.
Human molecular genetics
Chapuis J,Vingtdeux V,Campagne F,Davies P,Marambaud P
13-0200 was used in immunocytochemistry and western blot to investigate the role of growth arrest-specific 1 in Alzheimer's disease
Sun May 15 00:00:00 UTC 2011
Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor protein.
Human molecular genetics
Chapuis J,Vingtdeux V,Campagne F,Davies P,Marambaud P
13-0200 was used in immunocytochemistry and western blot to investigate the role of growth arrest-specific 1 in Alzheimer's disease
Sun May 15 00:00:00 UTC 2011
Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor protein.
Human molecular genetics
Chapuis J,Vingtdeux V,Campagne F,Davies P,Marambaud P
13-0200 was used in immunocytochemistry and western blot to investigate the role of growth arrest-specific 1 in Alzheimer's disease
Sun May 15 00:00:00 UTC 2011
Identification of novel N-terminal fragments of amyloid precursor protein in cerebrospinal fluid.
Experimental neurology
Portelius E,Brinkmalm G,Tran A,Andreasson U,Zetterberg H,Westman-Brinkmalm A,Blennow K,Ohrfelt A
13-0200 was used in western blot to search for N-terminal fragments of amyloid precursor protein in cerebrospinal fluid
Tue Jun 01 00:00:00 UTC 2010
Alphab-crystallin is a target for adaptive immune responses and a trigger of innate responses in preactive multiple sclerosis lesions.
Journal of neuropathology and experimental neurology
van Noort JM,Bsibsi M,Gerritsen WH,van der Valk P,Bajramovic JJ,Steinman L,Amor S
13-0200 was used in western blot to compare the serum immunoglobulin G reactivity profiles obtained using the full spectrum of human myelin-associated proteins of multiple sclerosis patients and healthy control subjects.
Thu Jul 01 00:00:00 UTC 2010
AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.
The Journal of biological chemistry
Vingtdeux V,Giliberto L,Zhao H,Chandakkar P,Wu Q,Simon JE,Janle EM,Lobo J,Ferruzzi MG,Davies P,Marambaud P
13-0200 was used in immunocytochemistry to investigate resveratrol's regulation of AMP-activated protein kinase
Fri Mar 19 00:00:00 UTC 2010
AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.
The Journal of biological chemistry
Vingtdeux V,Giliberto L,Zhao H,Chandakkar P,Wu Q,Simon JE,Janle EM,Lobo J,Ferruzzi MG,Davies P,Marambaud P
13-0200 was used in immunocytochemistry to investigate resveratrol's regulation of AMP-activated protein kinase
Fri Mar 19 00:00:00 UTC 2010
AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.
The Journal of biological chemistry
Vingtdeux V,Giliberto L,Zhao H,Chandakkar P,Wu Q,Simon JE,Janle EM,Lobo J,Ferruzzi MG,Davies P,Marambaud P
13-0200 was used in immunocytochemistry to investigate resveratrol's regulation of AMP-activated protein kinase
Fri Mar 19 00:00:00 UTC 2010
Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease.
PloS one
Willuweit A,Velden J,Godemann R,Manook A,Jetzek F,Tintrup H,Kauselmann G,Zevnik B,Henriksen G,Drzezga A,Pohlner J,Schoor M,Kemp JA,von der Kammer H
Fri Nov 20 00:00:00 UTC 2009
Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease.
PloS one
Willuweit A,Velden J,Godemann R,Manook A,Jetzek F,Tintrup H,Kauselmann G,Zevnik B,Henriksen G,Drzezga A,Pohlner J,Schoor M,Kemp JA,von der Kammer H
Fri Nov 20 00:00:00 UTC 2009
CNI-1493 inhibits Abeta production, plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease.
The Journal of experimental medicine
Bacher M,Dodel R,Aljabari B,Keyvani K,Marambaud P,Kayed R,Glabe C,Goertz N,Hoppmann A,Sachser N,Klotsche J,Schnell S,Lewejohann L,Al-Abed Y
13-0200 was used in Western Blotting to demonstrate that CNI-1493, a tetravalent guanylhydrazone with established antiinflammatory properties, interferes with amyloid beta assembly and protects neuronal cells from the toxic effect of soluble amyloid beta oligomers.
Mon Jul 07 00:00:00 UTC 2008
Autosomal dominant sensory ataxia: a neuroaxonal dystrophy.
Acta neuropathologica
Moeller JJ,Macaulay RJ,Valdmanis PN,Weston LE,Rouleau GA,Dupré N
13-0200 was used in immunohistochemistry to study the case of a 61-year-old man with autosomal dominant sensory ataxia who died of congestive heart failure
Mon Sep 01 00:00:00 UTC 2008
Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
Journal of neurochemistry
Ryoo SR,Cho HJ,Lee HW,Jeong HK,Radnaabazar C,Kim YS,Kim MJ,Son MY,Seo H,Chung SH,Song WJ
13-0200 was used in immunocytochemistry to investigate the regulatory link between beta-amyloid precursor protein and dual-specificity tyrosine(Y)-phosphorylation regulated kinase A in Down syndrome brains.
Sat Mar 01 00:00:00 UTC 2008
Natural host genetic resistance to lentiviral CNS disease: a neuroprotective MHC class I allele in SIV-infected macaques.
PloS one
Mankowski JL,Queen SE,Fernandez CS,Tarwater PM,Karper JM,Adams RJ,Kent SJ
13-0200 was used in immunohistochemistry - paraffin section to assess the relationship between expression of the MHC class I allele Mane-A*10 and development of lentiviral-induced central nervous system disease
Tue Feb 03 00:00:00 UTC 2009
Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury.
Journal of neurotrauma
Ai J,Liu E,Wang J,Chen Y,Yu J,Baker AJ
13-0200 was used in immunohistochemistry - paraffin section to examine the role of calpain activation in the corpus callosum in traumatic brain injury
Fri Jun 01 00:00:00 UTC 2007
Expression of APP pathway mRNAs and proteins in Alzheimer's disease.
Brain research
Matsui T,Ingelsson M,Fukumoto H,Ramasamy K,Kowa H,Frosch MP,Irizarry MC,Hyman BT
13-0200 was used in ELISA to test if sporadic cases of Alzheimer's disease are associated with changes in transcription of amyloid precursor protein or its metabolic partners
Fri Aug 03 00:00:00 UTC 2007
Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling.
The Journal of biological chemistry
Nizzari M,Venezia V,Repetto E,Caorsi V,Magrassi R,Gagliani MC,Carlo P,Florio T,Schettini G,Tacchetti C,Russo T,Diaspro A,Russo C
13-0200 was used in immunocytochemistry to propose that amyloid precursor protein and presenilin1 are part of a common signaling pathway that regulates ERK1,2 and the cell cycle
Fri May 04 00:00:00 UTC 2007
Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling.
The Journal of biological chemistry
Nizzari M,Venezia V,Repetto E,Caorsi V,Magrassi R,Gagliani MC,Carlo P,Florio T,Schettini G,Tacchetti C,Russo T,Diaspro A,Russo C
13-0200 was used in immunocytochemistry to propose that amyloid precursor protein and presenilin1 are part of a common signaling pathway that regulates ERK1,2 and the cell cycle
Fri May 04 00:00:00 UTC 2007
Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling.
The Journal of biological chemistry
Nizzari M,Venezia V,Repetto E,Caorsi V,Magrassi R,Gagliani MC,Carlo P,Florio T,Schettini G,Tacchetti C,Russo T,Diaspro A,Russo C
13-0200 was used in immunocytochemistry to propose that amyloid precursor protein and presenilin1 are part of a common signaling pathway that regulates ERK1,2 and the cell cycle
Fri May 04 00:00:00 UTC 2007
A preliminary neuropathological study of Japanese encephalitis in humans and a mouse model.
Transactions of the Royal Society of Tropical Medicine and Hygiene
German AC,Myint KS,Mai NT,Pomeroy I,Phu NH,Tzartos J,Winter P,Collett J,Farrar J,Barrett A,Kipar A,Esiri MM,Solomon T
13-0200 was used in immunohistochemistry - paraffin section to examine brain material from four fatal human cases of Japanese encephalitis virus infection
Fri Dec 01 00:00:00 UTC 2006
Fatal familial insomnia with an unusual prion protein deposition pattern: an autopsy report with an experimental transmission study.
Neuropathology and applied neurobiology
Sasaki K,Doh-ura K,Wakisaka Y,Tomoda H,Iwaki T
13-0200 was used in immunohistochemistry - paraffin section to present the case of a Japanese patient who had a prion protein gene mutation responsible for fatal familial insomnia
Tue Feb 01 00:00:00 UTC 2005
14-3-3 protein in CSF: an early predictor of SIV CNS disease.
Journal of neuropathology and experimental neurology
Helke KL,Queen SE,Tarwater PM,Turchan-Cholewo J,Nath A,Zink MC,Irani DN,Mankowski JL
13-0200 was used in immunohistochemistry to investigate the role 14-3-3 proteins in the pathogenesis of central nervous system.
Tue Mar 01 00:00:00 UTC 2005
Contributors to white matter damage in the frontal lobe in Alzheimer's disease.
Neuropathology and applied neurobiology
Chalmers K,Wilcock G,Love S
13-0200 was used in ELISA, Immunohistochemistry, Western Blot to suggest that severity of frontal white matter damage in AD is closely related to parenchymal Abeta load and that in most cases the contribution of degenerative vascular disease, CAA and APOE is relatively minor.
Thu Dec 01 00:00:00 UTC 2005
L-glutamate and phorbol ester stimulate the release of secretory amyloid precursor protein from rat cortical synaptosomes.
Acta biologica Hungarica
Kirazov L,Kirazovi E,Schliebs R
13-0200 was used in western blot to investigate the effect of L-glutamate treatment on the secreted form of amyloid precursor protein
Mon Oct 24 00:00:00 UTC 2005
Decreased levels of soluble amyloid beta-protein precursor and beta-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus.
Arthritis research & therapy
Trysberg E,Höglund K,Svenungsson E,Blennow K,Tarkowski A
13-0200 was used in ELISA to determine the soluble molecules in cerebrospinal fluid that indicate axonal degeneration and amyloidogenesis
Fri Oct 07 00:00:00 UTC 2005
Progressive cognitive impairment and anxiety induction in the absence of plaque deposition in C57BL/6 inbred mice expressing transgenic amyloid precursor protein.
Journal of neuroscience research
Lee KW,Lee SH,Kim H,Song JS,Yang SD,Paik SG,Han PL
13-0200 was used in immunohistochemistry - paraffin section and western blot to develop and characterize a new mouse model of Alzheimer's disease
Sat May 15 00:00:00 UTC 2004
Progressive cognitive impairment and anxiety induction in the absence of plaque deposition in C57BL/6 inbred mice expressing transgenic amyloid precursor protein.
Journal of neuroscience research
Lee KW,Lee SH,Kim H,Song JS,Yang SD,Paik SG,Han PL
13-0200 was used in immunohistochemistry - paraffin section and western blot to develop and characterize a new mouse model of Alzheimer's disease
Sat May 15 00:00:00 UTC 2004
Fe65 is not involved in the platelet-derived growth factor-induced processing of Alzheimer's amyloid precursor protein, which activates its caspase-directed cleavage.
The Journal of biological chemistry
Zambrano N,Gianni D,Bruni P,Passaro F,Telese F,Russo T
Fri Apr 16 00:00:00 UTC 2004
Impact mechanics and axonal injury in a sheep model.
Journal of neurotrauma
Anderson RW,Brown CJ,Blumbergs PC,McLean AJ,Jones NR
13-0200 was used in immunohistochemistry - paraffin section to describe a biomechanical study of axonal injury due to a blunt impact to the head
Wed Oct 01 00:00:00 UTC 2003
Central nervous system correlates of behavioral deficits following simian immunodeficiency virus infection.
Journal of neurovirology
Weed MR,Hienz RD,Brady JV,Adams RJ,Mankowski JL,Clements JE,Zink MC
13-0200 was used in immunohistochemistry to investigate HIV/SIV CNS infection and damage.
Fri Aug 01 00:00:00 UTC 2003
Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease.
Neuroscience
Richardson JC,Kendal CE,Anderson R,Priest F,Gower E,Soden P,Gray R,Topps S,Howlett DR,Lavender D,Clarke NJ,Barnes JC,Haworth R,Stewart MG,Rupniak HT
13-0200 was used in western blot characterize mice that overexpress the Swedish double familial Alzheimer's disease mutation
Fri Mar 19 00:00:00 UTC 2004
Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism.
The Journal of biological chemistry
Araki Y,Tomita S,Yamaguchi H,Miyagi N,Sumioka A,Kirino Y,Suzuki T
13-0200 was used in western blot to investigate the role of Alcadein in Alzheimer's disease.
Fri Dec 05 00:00:00 UTC 2003
Disruption of corticocortical connections ameliorates amyloid burden in terminal fields in a transgenic model of Abeta amyloidosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Sheng JG,Price DL,Koliatsos VE
Fri Nov 15 00:00:00 UTC 2002
Accumulation of beta-amyloid precursor protein in axons correlates with CNS expression of SIV gp41.
Journal of neuropathology and experimental neurology
Mankowski JL,Queen SE,Tarwater PM,Fox KJ,Perry VH
13-0200 was used in immunohistochemistry to investigate the mechanisms of axonal damage associated with HIV central nervous system infection.
Tue Jan 01 00:00:00 UTC 2002
Endosomal sorting of amyloid precursor protein-P-selectin chimeras influences secretase processing.
Traffic (Copenhagen, Denmark)
Daugherty BL,Green SA
13-0200 was used in western blot to determine the role of endocytic compartments in beta-secretase processing of amyloid precursor protein.
Sat Dec 01 00:00:00 UTC 2001
The protease inhibitor, MG132, blocks maturation of the amyloid precursor protein Swedish mutant preventing cleavage by beta-Secretase.
The Journal of biological chemistry
Steinhilb ML,Turner RS,Gaut JR
13-0200 was used in ELISA to examine MG132 inhibition of beta-secretase cleavage.
Fri Feb 09 00:00:00 UTC 2001
Human bleomycin hydrolase regulates the secretion of amyloid precursor protein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lefterov IM,Koldamova RP,Lazo JS
13-0200 was used in immunoprecipitation and western blot to elucidate the regulatory role of human bleomycin hydrolase in the amyloid precursor protein processing pathways.
Fri Sep 01 00:00:00 UTC 2000
Sporadic inclusion body myositis correlates with increased expression and cross-linking by transglutaminases 1 and 2.
The Journal of biological chemistry
Choi YC,Park GT,Kim TS,Sunwoo IN,Steinert PM,Kim SY
Fri Mar 24 00:00:00 UTC 2000
Sporadic inclusion body myositis correlates with increased expression and cross-linking by transglutaminases 1 and 2.
The Journal of biological chemistry
Choi YC,Park GT,Kim TS,Sunwoo IN,Steinert PM,Kim SY
Fri Mar 24 00:00:00 UTC 2000
Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein.
The Journal of biological chemistry
Tomita S,Ozaki T,Taru H,Oguchi S,Takeda S,Yagi Y,Sakiyama S,Kirino Y,Suzuki T
13-0200 was used in immunocytochemistry to characterize human X11-like.
Fri Jan 22 00:00:00 UTC 1999
Neurofibrillary lesions in experimental aluminum-induced encephalopathy and Alzheimer's disease share immunoreactivity for amyloid precursor protein, A beta, alpha 1-antichymotrypsin and ubiquitin-protein conjugates.
Brain research
Huang Y,Herman MM,Liu J,Katsetos CD,Wills MR,Savory J
13-0200 was used in immunohistochemistry (paraffin) and western blot to study aluminum maltolate-induced neurofibrillary degeneration in rabbits.
Fri Oct 17 00:00:00 UTC 1997
A novel protein, amyloid precursor-like protein 2, is present in human brain, cerebrospinal fluid and conditioned media.
The Biochemical journal
Webster MT,Groome N,Francis PT,Pearce BR,Sherriff FE,Thinakaran G,Felsenstein KM,Wasco W,Tanzi RE,Bowen DM
13-0200 was used in immunohistochemistry (paraffin) to study 3B11 immunoreactivity in the human brain.
Tue Aug 15 00:00:00 UTC 1995
Markers of axonal injury in post mortem human brain.
Acta neuropathologica
Sherriff FE,Bridges LR,Gentleman SM,Sivaloganathan S,Wilson S
Thu Mar 09 00:00:00 UTC 1995
