Proteintech

Angiogenin Polyclonal Antibody

Angiogenin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Angiogenin Antibody (18302-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human liver tissue slide using 18302-1-AP ( Angiogenin antibody at dilution of 1:100 (under 40x lens).

Angiogenin Antibody in Western Blot (WB)

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Product Details

18302-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Product Specifications

Species Reactivity

Human

Published species

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.

Neuroscience bulletin

Zhang Y,Zhao X,Guo C,Zhang Y,Zeng F,Yin Q,Li Z,Shao L,Zhou D,Liu L

Fri Sep 01 00:00:00 UTC 2023

MicroRNA-3064-5p sponged by MALAT1 suppresses angiogenesis in human hepatocellular carcinoma by targeting the FOXA1/CD24/Src pathway.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Zhang P,Ha M,Li L,Huang X,Liu C

Wed Jan 01 00:00:00 UTC 2020

Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer.

Frontiers in oncology

Tang H,Zheng J,Bai X,Yue KL,Liang JH,Li DY,Wang LP,Wang JL,Guo Q

Sat Mar 30 00:00:00 UTC 2024

Transplantation of Human Adipose Stem Cells Using Acellular Human Amniotic Membrane Improves Angiogenesis in Injured Endometrial Tissue in a Rat Intrauterine Adhesion Model.

Cell transplantation

Han X,Ma Y,Lu X,Li W,Xia E,Li TC,Zhang H,Huang X

Thu Jun 24 00:00:00 UTC 2021

Sphingosine kinase 1/sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 pathway: A novel target of geniposide to inhibit angiogenesis.

Life sciences

Sun M,Deng R,Wang Y,Wu H,Zhang Z,Bu Y,Zhang H

Tue Sep 01 00:00:00 UTC 2020

Bone Marrow-Derived Mesenchymal Stem Cells Repair Necrotic Pancreatic Tissue and Promote Angiogenesis by Secreting Cellular Growth Factors Involved in the SDF-1 α /CXCR4 Axis in Rats.

Stem cells international

Qian D,Gong J,He Z,Hua J,Lin S,Xu C,Meng H,Song Z

Thu Mar 26 00:00:00 UTC 2015

Bone Marrow-Derived Mesenchymal Stem Cells Repair Necrotic Pancreatic Tissue and Promote Angiogenesis by Secreting Cellular Growth Factors Involved in the SDF-1 α /CXCR4 Axis in Rats.

Stem cells international

Qian D,Gong J,He Z,Hua J,Lin S,Xu C,Meng H,Song Z

Thu Mar 26 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: Angiogenin; angiogenin, ribonuclease, RNase A family, 5; epididymis luminal protein 168; MGC22466; MGC71966; Ribonuclease 5; ribonuclease A A1; ribonuclease A family member 5; RNase 5

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Gene Aliases: ALS9; ANG; HEL168; RAA1; RNASE4; RNASE5

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UniProt ID: (Human) P03950

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Entrez Gene ID: (Human) 283

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Function(s)

DNA binding actin binding endonuclease activity ribonuclease activity receptor binding copper ion binding protein binding heparin binding rRNA binding peptide binding protein homodimerization activity

Process(es)

angiogenesis ovarian follicle development oocyte maturation response to hypoxia response to yeast placenta development positive regulation of endothelial cell proliferation diacylglycerol biosynthetic process cell communication activation of phospholipase C activity rRNA transcription response to hormone cell migration negative regulation of translation antibacterial humoral response antifungal humoral response actin filament polymerization activation of protein kinase B activity activation of phospholipase A2 activity adherens junction organization positive regulation of phosphorylation homeostatic process innate immune response negative regulation of smooth muscle cell proliferation positive regulation of protein secretion defense response to Gram-positive bacterium RNA phosphodiester bond hydrolysis

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Angiogenin Polyclonal Antibody

Angiogenin Antibody (18302-1-AP) in IHC (P)

Product Details

18302-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Target Information

Bioinformatics

Performance Guarantee

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