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Annexin A11 Polyclonal Antibody

Annexin A11 Antibody in Immunocytochemistry (ICC/IF)

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Annexin A11 Antibody (10479-2-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using Annexin A11 antibody (Product # 10479-2-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red).

Annexin A11 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Annexin A11 Antibody in Western Blot (WB)

Annexin A11 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

10479-2-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:10-1:100

View 3 publications 3 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Annexin A11 Fusion Protein Ag0729 (1-180 aa encoded by BC007564)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSYPGYPPP PGGYPPAAPG GGPWGGAAYP PPPSMPPIGL DNVATYAGQF NQDYLSGMAA NMSGTFGGAN MPNLYPGAPG AGYPPVPPGG FGQPPSAQQP VPPYGMYPPP GGNPPSRMPS YPPYPGAPVP GQPMPPPGQQ PPGAYPGQPP VTYPGQPPVP LPGQQQPVPS YPGYPGSGTV T (1-180 aa encoded by BC007564)

Target Information

This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Transcript variants encoding the same isoform have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.

bioRxiv : the preprint server for biology

Nixon-Abell J,Ruggeri FS,Qamar S,Herling TW,Czekalska MA,Shen Y,Wang G,King C,Fernandopulle MS,Sneideris T,Watson JL,Pillai VVS,Meadows W,Henderson JW,Chambers JE,Wagstaff JL,Williams SH,Coyle H,Lu Y,Zhang S,Marciniak SJ,Freund SMV,Derivery E,Ward ME,Vendruscolo M,Knowles TPJ,St George-Hyslop P

Fri Mar 24 00:00:00 UTC 2023

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.

bioRxiv : the preprint server for biology

Fri Mar 24 00:00:00 UTC 2023

Adult-onset dominant muscular dystrophy in Greek families caused by Annexin A11.

Annals of clinical and translational neurology

Johari M,Papadimas G,Papadopoulos C,Xirou S,Kanavaki A,Chrysanthou-Piterou M,Rusanen S,Savarese M,Hackman P,Udd B

Sat Oct 01 00:00:00 UTC 2022

Urinary extracellular vesicles signature for diagnosis of kidney disease.

iScience

Takizawa K,Ueda K,Sekiguchi M,Nakano E,Nishimura T,Kajiho Y,Kanda S,Miura K,Hattori M,Hashimoto J,Hamasaki Y,Hisano M,Omori T,Okamoto T,Kitayama H,Fujita N,Kuramochi H,Ichiki T,Oka A,Harita Y

Fri Nov 18 00:00:00 UTC 2022

Genetic screening of ANXA11 revealed novel mutations linked to amyotrophic lateral sclerosis.

Neurobiology of aging

Teyssou E,Muratet F,Amador MD,Ferrien M,Lautrette G,Machat S,Boillée S,Larmonier T,Saker S,Leguern E,Cazeneuve C,Marie Y,Guegan J,Gyorgy B,Cintas P,Meininger V,Le Forestier N,Salachas F,Couratier P,Camu W,Seilhean D,Millecamps S

Mon Mar 01 00:00:00 UTC 2021

Genetic screening of ANXA11 revealed novel mutations linked to amyotrophic lateral sclerosis.

Neurobiology of aging

Mon Mar 01 00:00:00 UTC 2021

A Novel Multisystem Proteinopathy Caused by a Missense ANXA11 Variant.

Annals of neurology

Leoni TB,González-Salazar C,Rezende TJR,Hernández ALC,Mattos AHB,Coimbra Neto AR,da Graça FF,Gonçalves JPN,Martinez ARM,Taniguti L,Kitajima JP,Kok F,Rogério F,da Silva AMS,de Oliveira ALR,Zanoteli E,Nucci A,França MC

Sun Aug 01 00:00:00 UTC 2021

A Novel Multisystem Proteinopathy Caused by a Missense ANXA11 Variant.

Annals of neurology

Sun Aug 01 00:00:00 UTC 2021

Theme 2 Genetics and genomics.

Amyotrophic lateral sclerosis & frontotemporal degeneration

Roggenbuck J,Doyle C,Lincoln T,Glass J

Fri Nov 01 00:00:00 UTC 2019

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.

Science translational medicine

Smith BN,Topp SD,Fallini C,Shibata H,Chen HJ,Troakes C,King A,Ticozzi N,Kenna KP,Soragia-Gkazi A,Miller JW,Sato A,Dias DM,Jeon M,Vance C,Wong CH,de Majo M,Kattuah W,Mitchell JC,Scotter EL,Parkin NW,Sapp PC,Nolan M,Nestor PJ,Simpson M,Weale M,Lek M,Baas F,Vianney de Jong JM,Ten Asbroek ALMA,Redondo AG,Esteban-Pérez J,Tiloca C,Verde F,Duga S,Leigh N,Pall H,Morrison KE,Al-Chalabi A,Shaw PJ,Kirby J,Turner MR,Talbot K,Hardiman O,Glass JD,De Belleroche J,Maki M,Moss SE,Miller C,Gellera C,Ratti A,Al-Sarraj S,Brown RH,Silani V,Landers JE,Shaw CE

Wed May 03 00:00:00 UTC 2017

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.

Science translational medicine

Wed May 03 00:00:00 UTC 2017

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.

Science translational medicine

Wed May 03 00:00:00 UTC 2017

ANXA11 regulates the tumorigenesis, lymph node metastasis and 5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by targeting c-Jun.

Oncotarget

Liu S,Guo C,Wang J,Wang B,Qi H,Sun MZ

Tue Mar 29 00:00:00 UTC 2016

ANXA11 regulates the tumorigenesis, lymph node metastasis and 5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by targeting c-Jun.

Oncotarget

Liu S,Guo C,Wang J,Wang B,Qi H,Sun MZ

Tue Mar 29 00:00:00 UTC 2016

Annexin A11 knockdown inhibits in vitro proliferation and enhances survival of Hca-F cell via Akt2/FoxO1 pathway and MMP-9 expression.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Liu S,Wang J,Guo C,Qi H,Sun MZ

Sun Mar 01 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: 56 kDa autoantigen; Annexin A11; Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50); Annexin XI; Annexin-11; autoantigen; autoantigen, 56-kD; Calcyclin-associated annexin 50; CAP-50; OTTHUMP00000019957; OTTHUMP00000019958; RP11-369J21

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Gene Aliases: A830099O17Rik; ANX11; ANXA11; CAP50

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UniProt ID: (Human) P50995, (Mouse) P97384

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Entrez Gene ID: (Human) 311, (Rat) 290527, (Mouse) 11744

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Function(s)

calcium ion binding protein binding calcium-dependent phospholipid binding phosphatidylethanolamine binding MHC class II protein complex binding S100 protein binding poly(A) RNA binding calcium-dependent protein binding molecular_function

Process(es)

phagocytosis biological_process response to calcium ion cell cycle cell division

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Annexin A11 Polyclonal Antibody

Annexin A11 Antibody (10479-2-AP) in ICC/IF

Product Details

10479-2-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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