Proteintech

Annexin A2 Monoclonal Antibody (1C1E12)

Annexin A2 Antibody in Immunocytochemistry (ICC/IF)

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Annexin A2 Antibody (66035-1-IG) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed T-47D cells using Annexin A2 antibody (Product # 66035-1-Ig), at dilution of 1:500 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L).

Annexin A2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Annexin A2 Antibody in Western Blot (WB)

Annexin A2 Antibody in Flow Cytometry (Flow)

Product Image Gallery

Product Details

66035-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 10 publications 10 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:250-1:1,000

Immunocytochemistry (ICC/IF)

1:20-1:200

View 7 publications 7 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

Assay-dependent

View 5 publications 5 publications

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

1C1E12

Immunogen

Annexin A2 Fusion Protein Ag16654 (1-339 aa encoded by BC016774)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSTVHEILC KLSLEGDHST PPSAYGSVKA YTNFDAERDA LNIETAIKTK GVDEVTIVNI LTNRSNAQRQ DIAFAYQRRT KKELASALKS ALSGHLETVI LGLLKTPAQY DASELKASMK GLGTDEDSLI EIICSRTNQE LQEINRVYKE MYKTDLEKDI ISDTSGDFRK LMVALAKGRR AEDGSVIDYE LIDQDARDLY DAGVKRKGTD VPKWISIMTE RSVPHLQKVF DRYKSYSPYD MLESIRKEVK GDLENAFLNL VQCIQNKPLY FADRLYDSMK GKGTRDKVLI RIMVSRSEVD MLKIRSEFKR KYGKSLYYYI QQDTKGDYQK ALLYLCGGDD (1-339 aa encoded by BC016774)

Target Information

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.

The Journal of nutritional biochemistry

Zhang M,Li X,Cui X,Li R,Ma Z,Gao X

Mon May 01 00:00:00 UTC 2023

Analysis of Dysferlin Direct Interactions with Putative Repair Proteins Links Apoptotic Signaling to Ca²⁺ Elevation via PDCD6 and FKBP8.

International journal of molecular sciences

Drescher DG,Drescher MJ,Selvakumar D,Annam NP

Tue Feb 28 00:00:00 UTC 2023

Annexin A2 promotes angiogenesis after ischemic stroke via annexin A2 receptor - AKT/ERK pathways.

Neuroscience letters

Lin H,Li W,Shen Z,Bei Y,Wei T,Yu Z,Dai Y,Dai H

Sun Jan 01 00:00:00 UTC 2023

Hypoxia-induced circADAMTS6 in a TDP43-dependent manner accelerates glioblastoma progression via ANXA2/ NF-κB pathway.

Oncogene

Zhao S,Li B,Zhao R,Pan Z,Zhang S,Qiu W,Guo Q,Qi Y,Gao Z,Fan Y,Xu H,Li M,Zhang J,Wang H,Xu J,Wang S,Wang Q,Qiu J,Deng L,Guo X,Zhang P,Xue H,Li G

Sun Jan 01 00:00:00 UTC 2023

Hypoxia-induced circADAMTS6 in a TDP43-dependent manner accelerates glioblastoma progression via ANXA2/ NF-κB pathway.

Oncogene

Zhao S,Li B,Zhao R,Pan Z,Zhang S,Qiu W,Guo Q,Qi Y,Gao Z,Fan Y,Xu H,Li M,Zhang J,Wang H,Xu J,Wang S,Wang Q,Qiu J,Deng L,Guo X,Zhang P,Xue H,Li G

Sun Jan 01 00:00:00 UTC 2023

Hypoxia-induced circADAMTS6 in a TDP43-dependent manner accelerates glioblastoma progression via ANXA2/ NF-κB pathway.

Oncogene

Zhao S,Li B,Zhao R,Pan Z,Zhang S,Qiu W,Guo Q,Qi Y,Gao Z,Fan Y,Xu H,Li M,Zhang J,Wang H,Xu J,Wang S,Wang Q,Qiu J,Deng L,Guo X,Zhang P,Xue H,Li G

Sun Jan 01 00:00:00 UTC 2023

Hypoxia-induced circADAMTS6 in a TDP43-dependent manner accelerates glioblastoma progression via ANXA2/ NF-κB pathway.

Oncogene

Zhao S,Li B,Zhao R,Pan Z,Zhang S,Qiu W,Guo Q,Qi Y,Gao Z,Fan Y,Xu H,Li M,Zhang J,Wang H,Xu J,Wang S,Wang Q,Qiu J,Deng L,Guo X,Zhang P,Xue H,Li G

Sun Jan 01 00:00:00 UTC 2023

Chip-DSF: A rapid screening strategy for drug protein targets.

Pharmacological research

Cui Z,Chen P,Li C,Deng S,Yang H

Mon Aug 01 00:00:00 UTC 2022

Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair.

FEBS letters

Yim WW,Yamamoto H,Mizushima N

Fri Apr 01 00:00:00 UTC 2022

Human epididymis protein 4 promotes P‑glycoprotein‑mediated chemoresistance in ovarian cancer cells through interactions with Annexin II.

Molecular medicine reports

Liu Q,Liu DW,Zheng MJ,Deng L,Wang HM,Jin S,Liu JJ,Hao YY,Zhu LC,Lin B

Thu Jul 01 00:00:00 UTC 2021

Human epididymis protein 4 promotes P‑glycoprotein‑mediated chemoresistance in ovarian cancer cells through interactions with Annexin II.

Molecular medicine reports

Liu Q,Liu DW,Zheng MJ,Deng L,Wang HM,Jin S,Liu JJ,Hao YY,Zhu LC,Lin B

Thu Jul 01 00:00:00 UTC 2021

Human epididymis protein 4 promotes P‑glycoprotein‑mediated chemoresistance in ovarian cancer cells through interactions with Annexin II.

Molecular medicine reports

Liu Q,Liu DW,Zheng MJ,Deng L,Wang HM,Jin S,Liu JJ,Hao YY,Zhu LC,Lin B

Thu Jul 01 00:00:00 UTC 2021

TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.

Cell death & disease

Zhang HT,Zeng Q,Wu B,Lu J,Tong KL,Lin J,Liu QY,Xu L,Yang J,Liu X,Liu W,Zhang YF,Lian Q,Liu L,Gao X

Wed Jan 06 00:00:00 UTC 2021

TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.

Cell death & disease

Zhang HT,Zeng Q,Wu B,Lu J,Tong KL,Lin J,Liu QY,Xu L,Yang J,Liu X,Liu W,Zhang YF,Lian Q,Liu L,Gao X

Wed Jan 06 00:00:00 UTC 2021

Chlorogenic acid inhibits the proliferation of human lung cancer A549 cell lines by targeting annexin A2 in vitro and in vivo.