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Invitrogen
Annexin A2 Recombinant Rabbit Monoclonal Antibody (1W2B5)
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FIGURE: 1 / 4
Annexin A2 Antibody (MA5-35086) in IHC (P)
Immunohistochemistry analysis of Annexin A2 in paraffin-embedded human esophageal. Samples were incubated with Annexin A2 Monoclonal antibody (Product # MA5-35086) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
MA5-35086
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1W2B5
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Annexin A2 (P07355)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2848991
Product Specific Information
Immunogen sequence: MSTVHEILCK LSLEGDHSTP PSAYGSVKAY TNFDAERDAL NIETAIKTKG VDEVTIVNIL TNRSNAQRQD IAFAYQRRTK KELASALKSA LSGHLETVIL
Target Information
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 33-kDa calcimedin; 33-kDa lymphocyte Ca<2+>- binding protein; 33kDa lymphocyte Ca<2+>- binding protein; 36-kDa calelectrin; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; calpactin I heavy polypeptide; Calpactin-1 heavy chain; chromobindin 8; Chromobindin-8; epididymis secretory protein Li 270; Lipocortin II; p36; PAP-IV; Placental anticoagulant protein IV; Protein I
Gene Aliases: ANX2; ANX2L4; ANXA2; AW215814; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV
UniProt ID: (Human) P07355, (Mouse) P07356, (Rat) Q07936
Entrez Gene ID: (Human) 302, (Mouse) 12306, (Rat) 56611
protease binding
calcium ion binding
protein binding
calcium-dependent phospholipid binding
phosphatidylinositol-4,5-bisphosphate binding
cytoskeletal protein binding
Rab GTPase binding
phospholipase A2 inhibitor activity
receptor activator activity
S100 protein binding
poly(A) RNA binding
calcium-dependent protein binding
cadherin binding involved in cell-cell adhesion
phospholipase inhibitor activity
actin filament binding
angiogenesis
membrane raft assembly
positive regulation of protein phosphorylation
negative regulation of receptor internalization
membrane budding
body fluid secretion
collagen fibril organization
positive regulation of vesicle fusion
negative regulation of low-density lipoprotein particle receptor catabolic process
osteoclast development
fibrinolysis
negative regulation of catalytic activity
positive regulation of fibroblast proliferation
positive regulation of binding
protein heterotetramerization
cellular response to acid chemical
protein targeting to plasma membrane
negative regulation of receptor binding
positive regulation of receptor activity
response to thyroid hormone
cell-cell adhesion
regulation of fibrinolysis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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