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Product Details
CL594-66245
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1E6A8
Immunogen
Full length Annexin V protein.
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Target Information
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Anchorin CII; Annexin A5; Annexin V; Annexin-5; Calphobindin I; CBP-I; CPB-I; Endonexin II; epididymis secretory protein Li 7; Lipocortin V; PAP-I; Placental anticoagulant protein 4; Placental anticoagulant protein I; PP4; Thromboplastin inhibitor; VAC-alpha; Vascular anticoagulant-alpha
Gene Aliases: ANX5; ANXA5; ENX2; HEL-S-7; PP4; RPRGL3
UniProt ID: (Human) P08758
Entrez Gene ID: (Human) 308
positive regulation of defense response to virus by host
signal transduction
blood coagulation
negative regulation of blood coagulation
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of catalytic activity
protein homooligomerization
response to calcium ion
calcium ion transmembrane transport
cellular response to lead ion
response to thyroid hormone
cellular response to gonadotropin-releasing hormone
mitophagy in response to mitochondrial depolarization
xenophagy
regulation of sperm motility
negative regulation of prolactin secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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