Alomone Labs, LTD

Anoctamin-6 (extracellular) Polyclonal Antibody, FITC

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

ACL-016-F-50UL

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

5 µg
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

(C)KLPKNINGTDPIQK, corresponding to amino acid residues 487-500 of human ANO6, 2nd extracellular loop
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Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra spectra

Form

Lyophilized

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 1% BSA

Contains

0.05% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Information

May act as a calcium-activated chloride channel.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Anoctamin-6; SCAN channel; Small-conductance calcium-activated nonselective cation channel; Transmembrane protein 16F

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Gene Aliases: 2900059G15Rik; AA407480; ANO6; AW554778; BDPLT7; F730003B03Rik; SCTS; TMEM16F

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UniProt ID: (Human) Q4KMQ2, (Mouse) Q6P9J9

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Entrez Gene ID: (Human) 196527, (Rat) 315272, (Mouse) 105722

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Function(s)
calcium activated cation channel activity intracellular calcium activated chloride channel activity voltage-gated ion channel activity voltage-gated chloride channel activity protein binding phospholipid scramblase activity protein homodimerization activity molecular_function chloride channel activity
Process(es)
dendritic cell chemotaxis activation of blood coagulation via clotting cascade cation transport chloride transport blood coagulation phospholipid transport phospholipid scrambling bone mineralization involved in bone maturation regulation of anion transport calcium activated phospholipid scrambling calcium activated phosphatidylserine scrambling calcium activated phosphatidylcholine scrambling calcium activated galactosylceramide scrambling phosphatidylserine exposure on apoptotic cell surface phosphatidylserine exposure on blood platelet cation transmembrane transport positive regulation of potassium ion export chloride transmembrane transport positive regulation of endothelial cell apoptotic process lipid transport positive regulation of bone mineralization bleb assembly ion transmembrane transport positive regulation of ion transmembrane transport purinergic nucleotide receptor signaling pathway sodium ion transmembrane transport positive regulation of apoptotic process negative regulation of cell volume pore complex assembly positive regulation of phagocytosis, engulfment calcium ion transmembrane transport positive regulation of monocyte chemotaxis regulation of anion transmembrane transport transport ion transport regulation of ion transmembrane transport
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