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Invitrogen
Apelin Polyclonal Antibody
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Product Details
PA5-95004
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Apelin (60-77aa RKFRRQRPRLSHKGPMPF).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806810
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: U87 Cell, MCF-7 Cell, HELA Cell, MM453 Cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AGTRL1 ligand; Apelin; apelin, AGTRL1 ligand; APJ endogenous ligand; preproapelin
Gene Aliases: 6030430G11Rik; APEL; APLN; XNPEP2
UniProt ID: (Human) Q9ULZ1, (Mouse) Q9R0R4, (Rat) Q9R0R3
Entrez Gene ID: (Human) 8862, (Mouse) 30878, (Rat) 58812
regulation of the force of heart contraction
immune response
signal transduction
lactation
positive regulation of cell proliferation
positive regulation of heat generation
positive regulation of phosphorylation
drinking behavior
regulation of respiratory gaseous exchange
negative regulation of blood pressure
negative regulation of vasoconstriction
positive regulation of vasodilation
positive regulation of corticotropin secretion
positive regulation of corticotropin-releasing hormone secretion
G-protein coupled receptor signaling pathway
feeding behavior
regulation of body fluid levels
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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