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Immunogen sequence: CCDQSGCKGT PHSSSAEKSA SYSSGHSQGP GPNMGKGGEQ MHEKSIPYSQ
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Dog: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 86%
APLNR (Apelin Receptor) is a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Angiotensin receptor-like 1; Apelin receptor; G-protein coupled receptor APJ; MSR
Gene Aliases: Agtrl1; APJ; Aplnr; msr/apj
UniProt ID: (Mouse) Q9WV08
Entrez Gene ID: (Mouse) 23796
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