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Invitrogen
Apelin Receptor Polyclonal Antibody
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Apelin Receptor Antibody (PA5-80343) in WB
Western blot was performed using Anti-Apelin Receptor Polyclonal Antibody (Product # PA5-80343) and a 42 kDa band corresponding to Apelin receptor was observed across cell lines tested. Whole cell extracts (20 µg lysate) of Hep G2 (Lane 1), K-562 (Lane 2), PC-3 (Lane 3), Daudi (Lane 4) and Jurkat (Lane 5) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Jurkat expresses APLNR protein at lower levels as compared to Daudi. Resolved proteins were then transferred onto a Nitrocellulose membrane (Product # IB... View More
Product Details
PA5-80343
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the N-terminus of the Human APJ Receptor/APLNR
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2787668
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human APJ Receptor/APLNR.
Target Information
APLNR (Apelin Receptor) is a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: angiotensin II receptor-like 1; Angiotensin receptor-like 1; Apelin receptor; APJ (apelin) receptor; APJ receptor; G protein-coupled receptor APJ; G-protein coupled receptor APJ; G-protein coupled receptor HG11; HG11 orphan receptor
Gene Aliases: AGTRL1; APJ; APJR; APLNR; HG11
UniProt ID: (Human) P35414
Entrez Gene ID: (Human) 187
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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