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NeoBiotechnologies
Apolipoprotein A4/apoA-IV Monoclonal Antibody (APOA4, 3372)
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Product Details
337-MSM2-P1
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
APOA4, 3372
Immunogen
Human recombinant APOA4 protein fragment (around aa 239-371)
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
Target Information
Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is an O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but evidence from several in vitro studies indicate that this apolipoprotein is involved in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apo-AIV; apoA-IV; Apolipoprotein A-IV; Apolipoprotein A4; MGC142154; MGC142156
Gene Aliases: APOA4
UniProt ID: (Human) P06727
Entrez Gene ID: (Human) 337
retinoid metabolic process
innate immune response in mucosa
cholesterol biosynthetic process
lipid transport
response to lipid hydroperoxide
leukocyte cell-cell adhesion
cholesterol metabolic process
positive regulation of cholesterol esterification
positive regulation of triglyceride catabolic process
removal of superoxide radicals
regulation of intestinal cholesterol absorption
neuron projection regeneration
regulation of cholesterol transport
cholesterol efflux
phospholipid efflux
chylomicron remodeling
very-low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
chylomicron assembly
high-density lipoprotein particle assembly
negative regulation of plasma lipoprotein particle oxidation
response to stilbenoid
lipoprotein metabolic process
lipoprotein biosynthetic process
cholesterol homeostasis
hydrogen peroxide catabolic process
reverse cholesterol transport
multicellular organism lipid catabolic process
cellular protein metabolic process
positive regulation of fatty acid biosynthetic process
phosphatidylcholine metabolic process
positive regulation of lipoprotein lipase activity
lipid homeostasis
protein-lipid complex assembly
triglyceride homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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