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Invitrogen
Aquaporin 3 Polyclonal Antibody
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Aquaporin 3 Antibody (PA5-78811) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of Aquaporin 3 in A431 cells using Aquaporin 3 Polyclonal Antibody (Product # PA5-78811). Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and incubated with the primary antibody at 5 µg/mL. Cy3 conjugated goat anti-rabbit IgG was used as secondary antibody at 1:500 diluti... View More
Product Details
PA5-78811
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 3 (278-292aa EENVKLAHVKHKEQI).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2745927
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, rat kidney tissue, mouse kidney tissue. IHC: mouse kidney tissue, rat kidney tissue, human bladder cancer tissue. ICC/IF: A431 cell. Flow: RT4 cell.
Target Information
AQP3 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 31.4 kDa water channel protein; AQP 3; AQP-3; Aquaglyceroporin-3; aquaporin 3 (GIL blood group); Aquaporin-3; Aquaporin3; Gill blood group
Gene Aliases: AQP-2; AQP-3; AQP3; GIL
UniProt ID: (Human) Q92482, (Rat) P47862, (Mouse) Q8R2N1
Entrez Gene ID: (Human) 360, (Rat) 65133, (Mouse) 11828
positive regulation of immune system process
renal water homeostasis
transport
water transport
excretion
cellular water homeostasis
glycerol transport
response to retinoic acid
response to vitamin D
ion transmembrane transport
odontogenesis
regulation of keratinocyte differentiation
response to calcium ion
renal water absorption
urea transmembrane transport
urea transport
carbohydrate transmembrane transport
transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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